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Structural Characterization and Heparanase Inhibitory Activity of Fucosylated Glycosaminoglycan from Holothuria floridana 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 3, 页码: 162
Authors:  Shi,Xiang;  Guan,Ruowei;  Zhou,Lutan;  Zuo,Zhichuang;  Tao,Xuelin;  Wang,Pin;  Zhou,Yanrong;  Yin,Ronghua;  Zhao,Longyan;  Gao,Na;  Zhao,Jinhua
Favorite  |  View/Download:151/0  |  Submit date:2022/04/02
Holothuria floridana  fucosylated glycosaminoglycans  oligosaccharide  chemical structure  heparanase  
From multi-target anticoagulants to DOACs, and intrinsic coagulation factor inhibitors 期刊论文
BLOOD REVIEWS, 2020
Authors:  Lin, Lisha;  Zhao, Longyan;  Gao, Na;  Yin, Ronghua;  Li, Sujuan;  Sun, Huifang;  Zhou, Lutan;  Zhao, Guiling;  Purcell, Steven W.;  Zhao, Jinhua
View  |  Adobe PDF(943Kb)  |  Favorite  |  View/Download:141/34  |  Submit date:2021/01/05
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
Authors:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
View  |  Adobe PDF(4714Kb)  |  Favorite  |  View/Download:377/48  |  Submit date:2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 5, 页码: 705-715
Authors:  Xiao, Chuang;  Zhao, Longyan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(740Kb)  |  Favorite  |  View/Download:295/81  |  Submit date:2019/06/24
nonasaccharide from fucosylated glycosaminoglycan  intrinsic factor Xase complex  factor IXa  anticoagulant  
Physicochemical Characteristics and Anticoagulant Activities of the Polysaccharides from Sea Cucumber Pattalus mollis 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 15
Authors:  Zheng, Wenqi;  Zhou, Lutan;  Lin, Lisha;  Cai, Ying;  Sun, Huifang;  Zhao, Longyan;  Gao, Na;  Yin, Ronghua;  Zhao, Jinhua
View  |  Adobe PDF(2958Kb)  |  Favorite  |  View/Download:247/40  |  Submit date:2019/06/24
Pattalus mollis  fucosylated glycosaminoglycan  fucan sulfate  physicochemical characteristics  anticoagulant activities  
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
Authors:  Guan, Ruowei;  Peng, Yuan;  Zhou, Lutan;  Zheng, Wenqi;  Liu, Xixi;  Wang, Pin;  Yuan, Qingxia;  Gao, Na;  Zhao, Longyan;  Zhao, Jinhua
View  |  Adobe PDF(2313Kb)  |  Favorite  |  View/Download:199/10  |  Submit date:2019/06/24
Apostichopus japonicus  fucosylated glycosaminoglycan  oligosaccharide  unambiguous structure  anti-Fxase  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
Authors:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(1313Kb)  |  Favorite  |  View/Download:257/47  |  Submit date:2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
Digestibility of fucosylated glycosaminoglycan from sea cucumber and its effects on digestive enzymes under simulated salivary and gastrointestinal conditions 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 186, 页码: 217-225
Authors:  Zhao, Longyan;  Qin, Yujing;  Guan, Ruowei;  Zheng, Wenqi;  Liu, Jikai;  Zhao, Jinhua
Favorite  |  View/Download:175/0  |  Submit date:2018/05/08
Sea Cucumber  Polysaccharide  Fucosylated Glycosaminoglycan  In Vitro Digestion  Digestive Enzyme  
Enzyme-Assisted Extraction Optimization, Characterization and Antioxidant Activity of Polysaccharides from Sea Cucumber Phyllophorus proteus 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 590
Authors:  Qin, Yujing;  Yuan, Qingxia;  Zhang, Yuexing;  Li, Jialu;  Zhu, Xinjiao;  Zhao, Lingling;  Wen, Jing;  Liu, Jikai;  Zhao, Longyan;  Zhao, Jinhua
View  |  Adobe PDF(5270Kb)  |  Favorite  |  View/Download:303/77  |  Submit date:2018/07/02
Sea Cucumber  Polysaccharide  Enzyme-assisted Extraction  Characterization  Antioxidant Activity  
Structural Characterization and Immunostirnulatory Activity of a Homogeneous Polysaccharide from Sinonovacula constricta 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2015, 卷号: 63, 期号: 36, 页码: 7986-7994
Authors:  Yuan,Qingxia;  Zhao,Longyan;  Cha,Qianqian;  Sun,Yi;  Ye,Hong;  Zeng,Xiaoxiong
View  |  Adobe PDF(2031Kb)  |  Favorite  |  View/Download:319/136  |  Submit date:2016/01/19
Sinonovacula Constricta  Polysaccharide  Structure  Immunomodulatory Activity