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Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
Authors:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
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cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
Structurally diverse steroids with nitric oxide inhibitory activities from Aglaia lawii leaves 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 183, 页码: 112651
Authors:  Li,Jin-Feng;  Ji,Kai-Long;  Sun,Peng;  Cai,Qiang;  Zheng,Xiao-Ling;  Xiao,Yi-Dian;  Cao,Dong-Hua;  Xiao,Chun-Fen;  Zhang,Zong-Yi;  Li,Xiao-Nian;  Hu,Hua-Bin;  Yu,Zhi-Yong;  Xu,You-Kai
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Aglaia lawii  Meliaceae  Steroids  Anti-inflammatory  Nitric oxide  PREGNANE STEROIDS  MARINE STEROLS  IDENTIFICATION  SKELETON  EPIMERS  
Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant 'tree of life' 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 4, 页码: nwaa105
Authors:  Zhang,Yongzeng;  Deng,Tao;  Sun,Lu;  Landis,Jacob B.;  Moore,Michael J.;  Wang,Hengchang;  Wang,Yuehua;  Hao,Xiaojiang;  Chen,Jijun;  Li,Shenghong;  Xu,Maonian;  Puno,Pema-Tenzin;  Raven,Peter H.;  Sun,Hang
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secondary metabolites  phylogenetic tree  phylogenetic signal  co-diversification  evolution  bioprospecting  seed plants  DIVERSIFICATION  EVOLUTION  DIVERSITY  SIGNAL  ANGIOSPERMS  CHEMISTRY  DEFENSES  FOSSIL  KEYS  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
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Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Tsaokols A and B, unusual flavanol-monoterpenoid hybrids as alpha-glucosidase inhibitors from Amomum tsao-ko 期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 3, 页码: 1202-1205
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
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Amomum tsao-ko  Zingiberaceae  Flavanol-monoterpenoid hybrids  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  CREVOST  
Discovery and heterologous production of sarubicins and quinazolinone C-glycosides with protecting activity for cardiomyocytes 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2021, 卷号: 8, 期号: 14, 页码: 3829-3837
Authors:  Yu,Mingming;  Luo,Jianying;  Luo,Dan;  He,Qiang;  Yan,Yijun;  Ji,Xu;  Huang,Sheng-Xiong
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STREPTOMYCES-VIOLACEORUBER TU22  BIOSYNTHESIS  GRANATICIN  ANTIBIOTICS  METABOLISM  MECHANISM  PATHWAY  ACID  
Structurally diverse limonoids and bio-active evaluation from Trichilia connaroides 期刊论文
FITOTERAPIA, 2021, 卷号: 153, 页码: 105001
Authors:  Cao,Dong-Hua;  Yao,Jian-Neng;  Sun,Peng;  Ji,Kai-Long;  Li,Xiao-Nian;  Cai,Qiang;  Xiao,Chun-Fen;  Hu,Hua-Bin;  Yu,Zhi-Yong;  Xu,You-Kai
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Trichilia connaroides  Meliaceae  Limonoid  Cytotoxicity  Anti-inflammatory  NITRIC-OXIDE PRODUCTION  CHEMICAL-CONSTITUENTS  CARBON SKELETON  RECENT PROGRESS  TETRANORTRITERPENOIDS  LEAVES  SEEDS  CHEMISTRY  STEROIDS  TWIGS  
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
Authors:  Lin,Lisha;  Li,Sujuan;  Gao,Na;  Wang,Weili;  Zhang,Taocui;  Yang,Lian;  Yang,Xingzhi;  Luo,Dan;  Ji,Xu;  Zhao,Jinhua
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fucosylated glycosaminoglycan  anticoagulant  platelet aggregation  contact activation  hypotension  pulmonary embolism  CHONDROITIN SULFATE  CONTACT SYSTEM  COMPLEMENT  COAGULATION  ACTIVATION  ACCUMULATION  INVOLVEMENT  DERIVATIVES  KALLIKREIN  THROMBOSIS  
Molecular networking uncovers steroidal saponins of Paris tengchongensis (vol 145, 104629, 2020) 期刊论文
FITOTERAPIA, 2021, 卷号: 150, 页码: 104830
Authors:  Wang,Jie;  Li,Dan;  Ni,Wei;  Qin,Xu-Jie;  Liu,Hui;  Yu,Ling-Ling;  Qiao,Xue;  Ji,Yun-Heng;  He,Li;  Nian,Si-Hui;  Liu,Hai-Yang
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Vasorelaxant 4,5-seco-abietane diterpenoids with diverse 6/6/6, 6/6/7, and 6/6/8 architectures from Salvia prattii Hemsl. 期刊论文
FITOTERAPIA, 2020
Authors:  Xia, Fan;  Luo, Dan;  Wang, Tingting;  Ji, Xu;  Xu, Gang
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