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Resveratrol Decrease Fructose-Induced Oxidative Stress Mediated by NADPH Oxidase via an AMPK-Dependent Mechanism1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
Authors:  Pei-Wen Cheng, PhD;  Wen-Yu Ho, MD, PhD;  Yu-Ting Su, MS;  Pei-Jung Lu,PhD;  Bo-Zone Chen MS;  Wen-Han Cheng, MS;  Wen-Hsien Lu, MD, MS;  Gwo-Ching Sun, MD;  Tung-Chen Yeh, MD;  Michael Hsiao DVM, PhD;  Ching-Jiunn Tseng, MD, PhD
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Ampk  Hypertension  Nucleus Tractus Solitarii  Nitrogen Oxides  Resveratrol  
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
Authors:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
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cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
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Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Discovery of Natural Co-occurring Enantiomers of Monoterpenoid Indole Alkaloids 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 4, 页码: 866-872
Authors:  Yu,Yang;  Bao,Mei-Fen;  Cai,Xiang-Hai
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Monoterpenoid indole alkaloid  Enantiomers  Tabovines A—  D  Structure elucidation| Extraction and isolation  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
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Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
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Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY  
Vincan- and eburnan-type alkaloids from Tabernaemontana bovina and their hypoglycemic activity 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 190, 页码: 112859
Authors:  Yu,Yang;  Bao,Mei-Fen;  Huang,Sheng-Zhuo;  Wu,Jing;  Cai,Xiang-Hai
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Tabernaemontana bovina  Apocynaceae  Vincan-type alkaloids  Eburnan-type alkaloids  Hypoglycemic activity  INDOLE ALKALOIDS  
Neo-clerodane Diterpenoids with Hypoglycemic Effects in Vivo from the Aerial Parts of Salvia hispanica L. 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 9, 页码: e2100517
Authors:  Fan,Min;  Wang,Ting;  Peng,Li-Yan;  Huang,Jun-Shang;  Wu,Xing-De;  Wang,He-Yao;  Zhao,Qin-Shi
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Salvia hispanica  neo-clerodane diterpenoid  salvihispin H  type 2 diabetes mellitus  GLUCOSE-TOLERANCE  RISK-FACTORS  THERAPY  
3-Hydroxy-4-methyldecanoic Acid-Containing Cyclotetradepsipeptides from an Endolichenic Beauveria sp. 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1244-1253
Authors:  Zhou,Yuan-Fei;  Hu,Kun;  Wang,Fang;  Tang,Jian-Wei;  Zhang,Liang;  Sun,Han-Dong;  Cai,Xiang-Hai;  Puno,Pema-Tenzin
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DOUBLE-BLIND  CYCLODEPSIPEPTIDES  CONFIGURATION  METABOLITES  SUROTOMYCIN  VANCOMYCIN  ADULTS  FUNGI  H-1  
Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities 期刊论文
TETRAHEDRON, 2021, 卷号: 79, 页码: 131783
Authors:  Shi,Bao-Bao;  Wang,Fang;  Chen,Gao;  Schinnerl,Johann;  Zeng,Ying;  Cai,Xiang-Hai
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Stemona mairei  Dihydrostilbenes  Structure elucidation  Quantum chemical calculation  Hypoglycemic activity assay  STILBENOIDS  CONFIGURATION  DERIVATIVES