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The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
作者:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
收藏  |  浏览/下载：72/0  |  提交时间：2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Development of a LC-HRMS based approach to boost structural annotation of isomeric citrus flavanones 期刊论文
PHYTOCHEMICAL ANALYSIS, 2021, 卷号: 32, 期号: 5, 页码: 749-756
作者:  He,Ying-Jie;  Zhou,Ying;  Qin,Yan;  Zhou,Zhong-Shun;  Zhu,Meng;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Xie,Tian-Zhen;  Zhao,Li-Xing;  Luo,Xiao-Dong
收藏  |  浏览/下载：90/0  |  提交时间：2022/04/02
citrus flavanones  collision energy  fragmentation pattern  high‐  resolution mass spectrometry  ion ratio  RESOLUTION MASS-SPECTROMETRY  HESPERETIN ENANTIOMERS  QUANTIFICATION  NARINGENIN  
Prostaglandin E1 Is an Efficient Molecular Tool for Forest Leech Blood Sucking 期刊论文
FRONTIERS IN VETERINARY SCIENCE, 2021, 卷号: 7, 页码: 615915
作者:  Zheng,Fenshuang;  Zhang,Min;  Yang,Xingwei;  Wu,Feilong;  Wang,Gan;  Feng,Xingxing;  Ombati,Rose;  Zuo,Ruiling;  Yang,Canju;  Liu,Jun;  Lai,Ren;  Luo,Xiaodong;  Long,Chengbo
收藏  |  浏览/下载：95/0  |  提交时间：2022/04/02
leech  blood-sucking  prostaglandin E1  anticoagulant  Haemadipsa sylvestris  MEDICINAL LEECH  PGE1  INFLAMMATION  THERAPY  PAIN  E-1  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2120Kb)  |  收藏  |  浏览/下载：190/46  |  提交时间：2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 1, 页码: 127-135
作者:  Zhao,Yun-Li;  Gou,Zhong-Ping;  Shang,Jian-Hua;  Li,Wan-Yi;  Kuang,Yu;  Li,Ming-Yuan;  Luo,Xiao-Dong
浏览  |  Adobe PDF(958Kb)  |  收藏  |  浏览/下载：111/34  |  提交时间：2022/04/02
Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 6, 页码: 651-658
作者:  Zhang,Ruo-Song;  Liu,Yang-Yang;  Zhu,Pei-Feng;  Jin,Qiong;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1291Kb)  |  收藏  |  浏览/下载：113/43  |  提交时间：2022/04/02
Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
作者:  Zhu,Pei-Feng;  Cheng,Gui-Guang;  Zhao,Lan-Qin;  Khan,Afsar;  Yang,Xing-Wei;  Zhang,Bu-Yun;  Li,Meng-Cheng;  Liu,Ya-Ping;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2113Kb)  |  收藏  |  浏览/下载：109/32  |  提交时间：2022/04/02
Rhynchanthus beesianus  diarylheptanoid  antioxidant activity  intracellular reactive oxygen species  cell apoptosis  GINGER ZINGIBER-OFFICINALE  PC12 CELLS  RHIZOMES  NEUROPROTECTION  ACTIVATION  ENZYMES  L.  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
浏览  |  Adobe PDF(5546Kb)  |  收藏  |  浏览/下载：128/45  |  提交时间：2022/04/02
Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
作者:  Chen,Ru;  Yin,Ronghua;  Li,Shanni;  Pan,Ying;  Mao,Hui;  Cai,Ying;  Lin,Lisha;  Wang,Weili;  Zhang,Taocui;  Zhou,Lutan;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua
浏览  |  Adobe PDF(3356Kb)  |  收藏  |  浏览/下载：96/26  |  提交时间：2022/04/02
Fucosylated glycosaminoglycan  Free radical depolymerization  Chemical structure  Oligosaccharide  NMR  INTRINSIC TENASE COMPLEX  ANTICOAGULANT ACTIVITIES  SEA-CUCUMBER  CHONDROITIN SULFATE  PHYSICOCHEMICAL CHARACTERISTICS  FACTOR XASE  POLYSACCHARIDES  DERIVATIVES  HEPARIN  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：160/84  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2