Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity.

doi:10.1007/s13659-021-00321-0

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	Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity.
	Zhang,Ruo-Song; Liu,Yang-Yang; Zhu,Pei-Feng; Jin,Qiong; Dai,Zhi; Luo,Xiao-Dong
	2021
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	11 期号:6 页码:651-658
摘要	Phytochemical investigation on the roots of Asparagus cochinchinensis led to the isolation of one new furostanol saponin, named 26-O-beta-D-glucopyranosyl-22alpha-hydroxyl-(25R)-Delta5(6)-furost-3beta,26-diol-3-O-alpha-L-rhamnopyranosyl-(12)-[beta-D-glucopyranosyl-(14)-alpha-L-rhamnopyranosyl-(14)]-beta-D-glucopyranoside (1), along with three known congeners (2‒4). The structure of new saponin was elucidated via comprehensive inspection of its HRMS and NMR spectral data as well as chemical technology, whereas those of known ones were identified by comparison of their NMR and MS spectral data with those reported in literatures. All isolated saponins were evaluated for their cytotoxic effects on two human liver (MHCC97H) and lung adenocarcinoma (H1299) cancer cells in vitro. Among them, both 1 and 2 showed significant cytotoxicity against above mentioned cell lines. Further studies revealed that these two saponins could significantly inhibit their proliferation of MHCC97H and H1299 cells.
DOI	10.1007/s13659-021-00321-0
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73793
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhang,Ruo-Song,Liu,Yang-Yang,Zhu,Pei-Feng,et al. Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity.[J]. Natural products and bioprospecting,2021,11(6):651-658.
APA	Zhang,Ruo-Song,Liu,Yang-Yang,Zhu,Pei-Feng,Jin,Qiong,Dai,Zhi,&Luo,Xiao-Dong.(2021).Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity..Natural products and bioprospecting,11(6),651-658.
MLA	Zhang,Ruo-Song,et al."Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity.".Natural products and bioprospecting 11.6(2021):651-658.

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