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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:105/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
Authors:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
Favorite  |  View/Download:25/0  |  Submit date:2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Biomimetic Synthesis of Lavandiolides H, I, and K and Artematrolide F via Diels-Alder Reaction 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 21, 页码: 8380-8384
Authors:  Li,Tian-Ze;  Yang,Xiao-Tong;  Wang,Jin-Ping;  Geng,Chang-An;  Ma,Yun-Bao;  Su,Li-Hua;  Zhang,Xue-Mei;  Chen,Ji-Jun
View  |  Adobe PDF(1317Kb)  |  Favorite  |  View/Download:22/1  |  Submit date:2022/04/02
TRIMERS  
Metabolic profiling of tyrosine kinase inhibitor nintedanib using metabolomics 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020
Authors:  Zhou, Zi-Meng;  Wang, Yi-Kun;  Yan, Dong-Mei;  Fang, Jian-He;  Xiao, Xue-Rong;  Zhang, Ting;  Cheng, Yan;  Xu, Kang-Ping;  Li, Fei
View  |  Adobe PDF(4095Kb)  |  Favorite  |  View/Download:73/14  |  Submit date:2021/01/05
Influence of P-glycoprotein on the disposition of fexofenadine and its enantiomers 期刊论文
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2017, 卷号: 69, 期号: 3, 页码: 274-284
Authors:  Li, Fei;  Howard, Karyn D.;  Myers, Michael J.
View  |  Adobe PDF(641Kb)  |  Favorite  |  View/Download:69/19  |  Submit date:2017/05/19
Abcb1-1 Delta  Collies  Enantiomer  Fexofenadine  Fluorescence  
Cognitive-enhancing effects of beta-sitosterol in vanadium-induced neurotoxicity in mice 期刊论文
JOURNAL OF NEUROCHEMISTRY, 2017, 卷号: 142, 页码: 238-238
Authors:  Adebiyi,O.;  Olayemi,F.;  Olopade,J.;  Ning-Hua,T.
View  |  Adobe PDF(878Kb)  |  Favorite  |  View/Download:101/44  |  Submit date:2017/10/23
胡椒属植物抗血小板和抗血栓活性研究进展 期刊论文
天然产物研究与开发, 2016, 期号: 10, 页码: 1676-1685
Authors:  夏梦媛;  王俐;  王跃虎
View  |  Adobe PDF(1155Kb)  |  Favorite  |  View/Download:236/44  |  Submit date:2016/12/19
胡椒属  抗血栓  抗血小板  抗凝血  
Can we safely target the WNT pathway? 期刊论文
NATURE REVIEWS DRUG DISCOVERY, 2014, 卷号: 13, 页码: 513
Authors:  Michael Kahn
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Hitting the Golden TORget: Curcumin's Effects on mTOR Signaling 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 7, 页码: 988-994
Authors:  Beevers, Christopher S.;  Zhou, Hongyu;  Huang, Shile
View  |  Adobe PDF(230Kb)  |  Favorite  |  View/Download:131/14  |  Submit date:2013/10/16
Curcumin  Mtor  Akt  Cancer  Cell Proliferation  Cell Death  
一类新型药物先导化合物的发现及其构效关系研究 学位论文
, 北京: 中国科学院大学, 2013
Authors:  陈铎之
Adobe PDF(4172Kb)  |  Favorite  |  View/Download:112/13  |  Submit date:2016/05/31
石蒜生物碱  抗hcv  Wnt 信号通路激动剂  构效关系研究  全合成