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ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
Authors:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
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conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Genomic and structural basis for evolution of tropane alkaloid biosynthesis 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 17, 页码: e2302448120
Authors:  Wang,Yong-Jiang;  Tain,Tian;  Yu,Jia-Yi;  Li,Jie;  Xu,Bingyan;  Chen,Jianghua;  D'Auria,John C.;  Huang,Jian-Ping;  Huang,Sheng-Xiong
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tropane alkaloids  evolution  biosynthesis  genome  structural biology  METHYLTRANSFERASE  REVEAL  
Editorial: Metabolism of plant natural products proceedings of annual meeting of CSPB2021 期刊论文
FRONTIERS IN PLANT SCIENCE, 2023, 卷号: 14, 页码: 1120573
Authors:  Huang,Sheng-Xiong;  Qi,Xiaoquan;  Wang,Yong
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metabolism  natural product  bioactive compounds  biosynthesis  metabolomics  
Catalytic innovation underlies independent recruitment of polyketide synthases in cocaine and hyoscyamine biosynthesis 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 4994
Authors:  Tian, Tian;  Wang, Yong-Jiang;  Huang, Jian-Ping;  Li, Jie;  Xu, Bingyan;  Chen, Yin;  Wang, Li;  Yang, Jing;  Yan, Yijun;  Huang, Sheng-Xiong
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TROPANE ALKALOID BIOSYNTHESIS  CHAIN-LENGTH CONTROL  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
Authors:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
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Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Tropane alkaloid biosynthesis: a centennial review 期刊论文
NATURAL PRODUCT REPORTS, 2021, 卷号: 38, 期号: 9, 页码: 1634-1658
Authors:  Huang,Jian-Ping;  Wang,Yong-Jiang;  Tian,Tian;  Wang,Li;  Yan,Yijun;  Huang,Sheng-Xiong
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PUTRESCINE N-METHYLTRANSFERASE  TRANSFORMED ROOT CULTURES  2 TROPINONE REDUCTASES  ROLLE DES ACETATS  DATURA-STRAMONIUM  HYOSCYAMUS-NIGER  TOBACCO ALKALOIDS  ORNITHINE-DECARBOXYLASE  2-OXOGLUTARATE-DEPENDENT DIOXYGENASE  DIFFERENT STEREOSPECIFICITIES  
Invertebrate-mediated dispersal plays an important role in shaping the current distribution of a herbaceous monocot 期刊论文
JOURNAL OF BIOGEOGRAPHY, 2021, 卷号: 48, 期号: 5, 页码: 1101-1111
Authors:  Chen,Yong-Sheng;  Zeng,Chun-Xia;  Muellner-Riehl,Alexandra N.;  Wang,Zhi-Heng;  Sun,Lu;  Schinnerl,Johann;  Kongkiatpaiboon,Sumet;  Kadota,Yuichi;  Cai,Xiang-Hai;  Chen,Gao
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biogeography  endemism  myrmecochory  Pandanales  Stemonaceae  vespicochory  CROOMIA STEMONACEAE  INTERCONTINENTAL DISJUNCTIONS  BIOLOGICAL-ACTIVITIES  FLORISTIC EXCHANGE  CHLOROPLAST DNA  SOUTHEAST-ASIA  PLANT  EVOLUTION  GENUS  DISTANCE  
Involucre fossils of Carpinus, a northern temperate element, from the Miocene of China and the evolution of its species diversity in East Asia 期刊论文
PLANT DIVERSITY, 2020
Authors:  Xue, Li;  Jia, Linbo;  Nam, Gi-soo;  Huang, Yongjiang;  Zhang, Shitao;  Wang, Yuqing;  Zhou, Zhuo;  Chen, Yongsheng
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Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis 期刊论文
PHYTOMEDICINE, 2020
Authors:  Wang Yu-Ling;  Wu Wei;  Su Yong-Nan;  Ai Zhi-Peng;  Mou Han-Chuan;  Wan Luo-Sheng;  Luo Ying;  Qiu Ming-Hua;  Zhang Ji-Hong
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Diterpenoids and Sesquiterpenoids from Syzygium fluviatile 期刊论文
RECORDS OF NATURAL PRODUCTS, 2020
Authors:  Zhang, Dingli;  Hu, Yikao;  Wang, Li;  Huang, Shengxiong;  Zhao, Yan;  Li, Mengjia;  Li, Feng;  Zhao, Yong
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