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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
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Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:214/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines 期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
Authors:  Ming-Ju Hsieh;  Chiao-Wen Lin;  Shun-Fa Yang;  Mu-Kuan Chen;  Hui-Ling Chiou
Adobe PDF(1320Kb)  |  Favorite  |  View/Download:213/1  |  Submit date:2017/07/24
Glabridin  Migration  Invasion  Matrix Metalloproteinase-9  Hepatoma  
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  Favorite  |  View/Download:346/1  |  Submit date:2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
Artemannuols A-C, novel sesquiterpenoid-flavonol hybrids with antihepatoma activity from Artemisia annua 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 26, 页码: 5451-5456
Authors:  He,Xiao-Feng;  Wang,Meng-Fei;  Li,Tian-Ze;  Ma,Yun-Bao;  Chen,Ji-Jun
View  |  Adobe PDF(556Kb)  |  Favorite  |  View/Download:32/6  |  Submit date:2024/07/25
Hepatocellular-carcinoma  Aggregation Pheromone  Bug  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
Authors:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
Adobe PDF(1447Kb)  |  Favorite  |  View/Download:41/13  |  Submit date:2024/05/09
Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
Authors:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
View  |  Adobe PDF(7197Kb)  |  Favorite  |  View/Download:13/3  |  Submit date:2024/07/30
PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
新型天然铁死亡诱导剂的筛选及作用机制研究 学位论文
: 中国科学院大学, 2022
Authors:  赵越勤
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肿瘤,天然产物,铁死亡,溶酶体,p53  Cancer, Nature products, Ferroptosis, Lysosome, p53  
Association of sirtuins (SIRT1-7) with lung and intestinal diseases 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2022, 卷号: 477, 期号: 11, 页码: 2539-2552
Authors:  Chen, Yuhan;  Zhou, Di;  Feng, Yuan;  Li, Bingxin;  Cui, Yong;  Chen, Gang;  Li, Ning
View  |  Adobe PDF(765Kb)  |  Favorite  |  View/Download:48/10  |  Submit date:2024/04/30
Sirtuins  Lung-intestinal axis  Inflammation  Tumors  MicroRNAs  ENDOPLASMIC-RETICULUM STRESS  EPITHELIAL-MESENCHYMAL TRANSITION  CANCER CELLS  ULCERATIVE-COLITIS  COLORECTAL-CANCER  DOWN-REGULATION  PROLIFERATION  SUPPRESSES  ACTIVATION  APOPTOSIS  
Wnt/β-catenin信号通路调控NK细胞介导的肿瘤免疫和Brevinin-1RL1抗肿瘤研究 学位论文
, 2021
Authors:  居晓曼
Adobe PDF(6895Kb)  |  Favorite  |  View/Download:19/0  |  Submit date:2024/03/20