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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  Favorite  |  View/Download：202/1  |  Submit date：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The compound BTB06584 is an IF1-dependent selective inhibitor of the mitochondrial F1Fo-ATPase1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-38
Authors:  Fabrice Ivanes;  Danilo Faccenda;  Jemma Gatliff;  Ahmed A Ahmed;  Stefania Cocco;  Carol Ho Ka Cheng;  Emma Allan;  Claire Russell;  Michael R Duchen;  Michelangelo Campanella
Adobe PDF(1228Kb)  |  Favorite  |  View/Download：148/1  |  Submit date：2017/07/24
Mitochondrial F1fo Atp Synthase  If1  Ischemia-induced Death  Btb06584  Pinotage  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download：105/1  |  Submit date：2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  Favorite  |  View/Download：242/1  |  Submit date：2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
Authors:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  Favorite  |  View/Download：120/1  |  Submit date：2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Tinospora cordifolia (Willd.) Miers: Protection mechanisms and strategies against oxidative stress-related diseases 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 283, 页码: 114540
Authors:  Arunachalm,Karuppusamy;  Yang,Xuefei;  San,Thae Thae
Favorite  |  View/Download：22/0  |  Submit date：2022/04/02
Tinospora cordifolia  Traditional medicine  Antioxidant  Reactive oxygen species  Immunomodulatory effect  COVID-19  CLERODANE FURANO-DITERPENE  INDIAN MEDICINAL-PLANTS  IN-VITRO ANTIOXIDANT  EX HOOK F  FREE-RADICALS  LIPID-PEROXIDATION  ETHANOLIC EXTRACT  AYURVEDIC FORMULATION  ALCOHOLIC EXTRACT  CARDIOPROTECTIVE ACTIVITY  
Mono-/Bis-Alkenoic Acid Derivatives From an Endophytic Fungus Scopulariopsis candelabrum and Their Antifungal Activity 期刊论文
FRONTIERS IN CHEMISTRY, 2022
Authors:  Tang, Jun;  Huang, Xueshuang;  Cao, Ming-Hang;  Wang, Zhiyan;  Yu, Zhiyin;  Yan, Yijun;  Huang, Jian-Ping;  Wang, Li;  Huang, Sheng-Xiong
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Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
Authors:  Wei,Ruiran;  Zhao,Yueqin;  Wang,Juan;  Yang,Xu;  Li,Shunlin;  Wang,Yinyuan;  Yang,Xingzhi;  Fei,Jimin;  Hao,Xiaojiang;  Zhao,Yuhan;  Gui,Liming;  Ding,Xiao
Favorite  |  View/Download：30/0  |  Submit date：2022/04/02
ferroptosis  tagitinin C  ROS  ER stress  Nrf2-HO-1 pathway  ENDOPLASMIC-RETICULUM STRESS  ER-STRESS  OXIDATIVE STRESS  TUMOR-SUPPRESSOR  NRF2  DEATH  IRON  DIFFERENTIATION  MECHANISMS  RESISTANCE  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
Adobe PDF(2120Kb)  |  Favorite  |  View/Download：46/3  |  Submit date：2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
Authors:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
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Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS