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Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris
Zhao,Yun-Li; Gou,Zhong-Ping; Shang,Jian-Hua; Li,Wan-Yi; Kuang,Yu; Li,Ming-Yuan; Luo,Xiao-Dong
2021
发表期刊Natural products and bioprospecting
ISSN2192-2195
卷号11期号:1页码:127-135
摘要Alstonia scholaris could be used as a traditional medicinal plant in China for the treatment of acute respiratory, which might be caused by respiratory tract infections. The investigation tested the anti-infective effects of total alkaloids extract (TA) from leaves of A. scholaris, and as a result, TA inhibited herpes simplex virus type 1 (HSV-1), respiratory syncytial virus (RSV) and influenza A virus (H1N1) in vitro respectively. In addition, the survival days of mice were prolonged, and the lung weights and mortality of mice were decreased significantly, after oral administrated TA in H1N1 and beta-hemolytic streptococcus infectious models in vivo respectively. The finding supported partly the traditional usage of A. scholaris in the treatment of respiratory infections.
DOI10.1007/s13659-020-00294-6
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/73808
专题中国科学院昆明植物研究所
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GB/T 7714
Zhao,Yun-Li,Gou,Zhong-Ping,Shang,Jian-Hua,et al. Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris[J]. Natural products and bioprospecting,2021,11(1):127-135.
APA Zhao,Yun-Li.,Gou,Zhong-Ping.,Shang,Jian-Hua.,Li,Wan-Yi.,Kuang,Yu.,...&Luo,Xiao-Dong.(2021).Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris.Natural products and bioprospecting,11(1),127-135.
MLA Zhao,Yun-Li,et al."Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris".Natural products and bioprospecting 11.1(2021):127-135.
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