Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris

doi:10.1007/s13659-020-00294-6

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	Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris
	Zhao,Yun-Li; Gou,Zhong-Ping; Shang,Jian-Hua; Li,Wan-Yi; Kuang,Yu; Li,Ming-Yuan; Luo,Xiao-Dong
	2021
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	11 期号:1 页码:127-135
摘要	Alstonia scholaris could be used as a traditional medicinal plant in China for the treatment of acute respiratory, which might be caused by respiratory tract infections. The investigation tested the anti-infective effects of total alkaloids extract (TA) from leaves of A. scholaris, and as a result, TA inhibited herpes simplex virus type 1 (HSV-1), respiratory syncytial virus (RSV) and influenza A virus (H1N1) in vitro respectively. In addition, the survival days of mice were prolonged, and the lung weights and mortality of mice were decreased significantly, after oral administrated TA in H1N1 and beta-hemolytic streptococcus infectious models in vivo respectively. The finding supported partly the traditional usage of A. scholaris in the treatment of respiratory infections.
DOI	10.1007/s13659-020-00294-6
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73808
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhao,Yun-Li,Gou,Zhong-Ping,Shang,Jian-Hua,et al. Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris[J]. Natural products and bioprospecting,2021,11(1):127-135.
APA	Zhao,Yun-Li.,Gou,Zhong-Ping.,Shang,Jian-Hua.,Li,Wan-Yi.,Kuang,Yu.,...&Luo,Xiao-Dong.(2021).Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris.Natural products and bioprospecting,11(1),127-135.
MLA	Zhao,Yun-Li,et al."Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris".Natural products and bioprospecting 11.1(2021):127-135.

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