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Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
作者:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(7289Kb)  |  收藏  |  浏览/下载：212/47  |  提交时间：2024/07/10
Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Sesquiterpenes from Carpesium faberi triggered ROS-induced apoptosis and protective autophagy in hepatocellular carcinoma cells 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113805
作者:  Yan,Ying;  Chen,Jie;  Peng,Mingyou;  Zhang,Xiong;  Feng,Enming;  Li,Qindan;  Guo,Bing;  Ding,Xiao;  Zhang,Yu;  Tang,Lei
浏览  |  Adobe PDF(4017Kb)  |  收藏  |  浏览/下载：157/42  |  提交时间：2024/07/25
Carpesium faberi (compositae)  Sesquiterpenes  Structural elucidation  Cytotoxic activities  Autophagy  LACTONE DIMERS  MYRRHANONE C  XANTHANOLIDES  TRITERPENE  HYBRIDS  ESTERS  
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:  Yan,Ying;  Ran,Xiaoqian;  Wang,Dan;  Zhang,Xiong;  Peng,Mingyou;  Yan,Xiaoyan;  Tang,Lei;  Liang,Hong;  Qin,Xujie;  Di,Ying-Tong;  Luo,Rongcan;  Hao,Xiao-Jiang;  Yao,Yong-Gang
浏览  |  Adobe PDF(1471Kb)  |  收藏  |  浏览/下载：254/88  |  提交时间：2024/07/25
UBIQUITIN-PROTEASOME SYSTEM  ALZHEIMERS-DISEASE  CONSTITUENTS  LIMONOIDS  TFEB  NEURODEGENERATION  
Quassinoids from Twigs of Harrisonia perforata (Blanco) Merr and Their Anti-Parkinson's Disease Effect 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 22, 页码: 16196
作者:  Cai,Min;  Bai,Xiao-Lin;  Zang,Hao-Jing;  Tang,Xiao-Han;  Yan,Ying;  Wan,Jia-Jia;  Peng,Min-You;  Liang,Hong;  Liu,Lin;  Guo,Feng;  Zhao,Pei-Ji;  Liao,Xun;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2612Kb)  |  收藏  |  浏览/下载：203/41  |  提交时间：2024/05/09
Harrisonia perforata  quassinoid  simarubaceae  neuroprotection  PC12 cells  PINK1(B9) flies  PROMISING BIOLOGICAL-ACTIVITY  UNPRECEDENTED QUASSINOIDS  
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088
作者:  Yan,Ying;  Zhou,Qi;  Ran,Xiaoqian;  Lu,Qingyun;  Zhang,Cuishan;  Peng,Mingyou;  Tang,Lei;  Luo,Rongcan;  Di,Yingtong;  Hao,Xiaojiang
浏览  |  Adobe PDF(11343Kb)  |  收藏  |  浏览/下载：223/37  |  提交时间：2024/05/09
euphjatrophane  Euphorbia peplus  jatrophane diterpenoid  autophagy  Tau pathology  UBIQUITIN-PROTEASOME SYSTEM  MULTIDRUG-RESISTANCE  BIOLOGICAL-ACTIVITY  ALZHEIMERS-DISEASE  MODULATORS  CELLS  
Enantioselective access to tricyclic tetrahydropyran derivatives by a remote hydrogen bonding mediated intramolecular IEDHDA reaction 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 7188
作者:  Jin,Min;  Tang,Congyun;  Li,Yingying;  Yang,Shuai;  Yang,Ying-Tao;  Peng,Lin;  Li,Xiao-Nian;  Zhang,Wenjing;  Zuo,Zhili;  Gagosz,Fabien;  Wang,Liang-Liang
浏览  |  Adobe PDF(2328Kb)  |  收藏  |  浏览/下载：372/73  |  提交时间：2022/04/02
DIELS-ALDER REACTION  BIOMIMETIC TOTAL-SYNTHESIS  ORTHO-QUINONE METHIDES  BRONSTED ACID  CYCLIZATION  ACTIVATION  OLEFINS  CYCLOADDITIONS  CATALYSIS  ENTRY  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
作者:  Wang,Gan;  Yang,Meng-Li;  Duan,Zi-Lei;  Liu,Feng-Liang;  Jin,Lin;  Long,Cheng-Bo;  Zhang,Min;  Tang,Xiao-Peng;  Xu,Ling;  Li,Ying-Chang;  Kamau,Peter Muiruri;  Yang,Lian;  Liu,Hong-Qi;  Xu,Jing-Wen;  Chen,Jie-Kai;  Zheng,Yong-Tang;  Peng,Xiao-Zhong;  Lai,Ren
收藏  |  浏览/下载：229/0  |  提交时间：2022/04/02
SARS  ENTRY  MERS  
The Chromosome-Based Rubber Tree Genome Provides New Insights into Spurge Genome Evolution and Rubber Biosynthesis 期刊论文
MOLECULAR PLANT, 2020, 卷号: 13, 期号: 2, 页码: 336-350
作者:  Liu, Jin;  Shi, Cong;  Shi, Cheng-Cheng;  Li, Wei;  Zhang, Qun-Jie;  Zhang, Yun;  Li, Kui;  Lu, Hui-Fang;  Shi, Chao;  Zhu, Si-Tao;  Xiao, Zai-Yun;  Nan, Hong;  Yue, Yao;  Zhu, Xun-Ge;  Wu, Yu;  Hong, Xiao-Ning;  Fan, Guang-Yi;  Tong, Yan;  Zhang, Dan;  Mao, Chang-Li;  Liu, Yun-Long;  Hao, Shi-Jie;  Liu, Wei-Qing;  Lv, Mei-Qi;  Zhang, Hai-Bin;  Liu, Yuan;  Hu-tang, Ge-Ran;  Wang, Jin-Peng;  Wang, Jia-Hao;  Sun, Ying-Huai;  Ni, Shu-Bang;  Chen, Wen-Bin;  Zhang, Xing-Cai;  Jiao, Yuan-Nian;  Eichler, Evan E.;  Li, Guo-Hua;  Liu, Xin;  Gao, Li-Zhi
收藏  |  浏览/下载：556/0  |  提交时间：2020/03/24
rubber tree  rubber biosynthesis  chromosome evolution  whole-genome duplication  domestication  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2020
作者:  Wang, Gan;  Yang, Meng-Li;  Duan, Zi-Lei;  Liu, Feng-Liang;  Jin, Lin;  Long, Cheng-Bo;  Zhang, Min;  Tang, Xiao-Peng;  Xu, Ling;  Li, Ying-Chang;  Kamau, Peter Muiruri;  Yang, Lian;  Liu, Hong-Qi;  Xu, Jing-Wen;  Chen, Jie-Kai;  Zheng, Yong-Tang;  Peng, Xiao-Zhong;  Lai, Ren
浏览  |  Adobe PDF(2926Kb)  |  收藏  |  浏览/下载：321/65  |  提交时间：2021/01/05
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：475/84  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines