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Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
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Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
Authors:  Wang,Gan;  Yang,Meng-Li;  Duan,Zi-Lei;  Liu,Feng-Liang;  Jin,Lin;  Long,Cheng-Bo;  Zhang,Min;  Tang,Xiao-Peng;  Xu,Ling;  Li,Ying-Chang;  Kamau,Peter Muiruri;  Yang,Lian;  Liu,Hong-Qi;  Xu,Jing-Wen;  Chen,Jie-Kai;  Zheng,Yong-Tang;  Peng,Xiao-Zhong;  Lai,Ren
Favorite  |  View/Download：31/0  |  Submit date：2022/04/02
SARS  ENTRY  MERS  
Non-volatile acylphloroglucinol components from Eucalyptus robusta inhibit Zika virus by impairing RdRp activity of NS5 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105303
Authors:  Yao,Zhai-Wen;  Liu,Hui;  Zhou,Rui;  Feng,Mi-Yan;  Wang,Fang;  Qin,Xu-Jie;  Chen,Xiu-Xiu;  Zheng,Chang-Bo;  Luo,Rong-Hua;  Yang,Liu-Meng;  Cen,Shan;  Xiong,Si-Dong;  Liu,Hai-Yang;  Zheng,Yong-Tang
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Eucalyptus robusta  Acylphloroglucinol dimer  Eucalyprobusone G  Anti-ZIKV agent  NS5 RdRp  INFECTION  BINDING  GROWTH  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2020
Authors:  Wang, Gan;  Yang, Meng-Li;  Duan, Zi-Lei;  Liu, Feng-Liang;  Jin, Lin;  Long, Cheng-Bo;  Zhang, Min;  Tang, Xiao-Peng;  Xu, Ling;  Li, Ying-Chang;  Kamau, Peter Muiruri;  Yang, Lian;  Liu, Hong-Qi;  Xu, Jing-Wen;  Chen, Jie-Kai;  Zheng, Yong-Tang;  Peng, Xiao-Zhong;  Lai, Ren
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Dimeric Pyranonaphthoquinone Glycosides with Anti-HIV and Cytotoxic Activities from a Soil-Derived Streptomyces 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 7, 页码: 1813-1819
Authors:  He, Xin;  Wang, Yongjiang;  Luo, Rong-Hua;  Yang, Liu-Meng;  Wang, Li;  Guo, Dale;  Yang, Jing;  Deng, Yun;  Zheng, Yong-Tang;  Huang, Sheng-Xiong
View  |  Adobe PDF(631Kb)  |  Favorite  |  View/Download：122/19  |  Submit date：2019/09/10
SJP-L-5 inhibits HIV-1 polypurine tract primed plus-strand DNA elongation, indicating viral DNA synthesis initiation at multiple sites under drug pressure 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 1, 页码: 2574
Authors:  Zhang, Xing-Jie;  Wang, Rui-Rui;  Chen, Huan;  Luo, Rong-Hua;  Yang, Liu-Meng;  Liu, Jing-Ping;  Sun, Han-Dong;  Zhang, Hong-Bin;  Xiao, Wei-Lie;  Zheng, Yong-Tang
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Compounds from the Roots of Codonopsis pilosula and Their SIRT1 Regulatory Activity 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2018, 卷号: 13, 期号: 1, 页码: 37-40
Authors:  Zheng, Tao;  Cheng, Li-Zhi;  Yan, Yong-Ming;  Xu, Fu-Rong;  Tang, Xiao-Long;  Li, Xiao-Zhen;  Qin, Fu-Ying;  Liu, Bao-Hua;  Cheng, Yong-Xian
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Codonopsis Pilosula  Pilosuloside a  Pilosulain a  Alkaloids  Terpenoids  
Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 9, 页码: 1498
Authors:  Chen, Huan;  Zhang, Rong;  Luo, Rong-Hua;  Yang, Liu-Meng;  Wang, Rui-Rui;  Hao, Xiao-Jiang;  Zheng, Yong-Tang
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Antiviral Agent  12-o-tricosanoylphorbol-20-acetate  Hiv  Vif  Apobec3g  Phorbol Ester  
Structural Characterization of Kadcoccinin A: A Sesquiterpenoid with a Tricyclo[4.4.0.0(3,10)]decane Scaffold from Kadsura coccinea 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 9, 页码: 2284-2287
Authors:  Hu, Zheng-Xi;  Shi, Yi-Ming;  Wang, Wei-Guang;  Tang, Jian-Wei;  Zhou, Min;  Du, Xue;  Zhang, Yong-Hui;  Pu, Jian-Xin;  Sun, Han-Dong
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SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry 期刊论文
BMC MICROBIOLOGY, 2015, 卷号: 15
Authors:  Bai,Ru;  Zhang,Xing-Jie;  Li,Yan-Li;  Liu,Jing-Ping;  Zhang,Hong-Bin;  Xiao,Wei-Lie;  Pu,Jian-Xin;  Sun,Han-Dong;  Zheng,Yong-Tang;  Liu,Li-Xin
Adobe PDF(2540Kb)  |  Favorite  |  View/Download：158/34  |  Submit date：2016/01/19
Hiv-1  Pre-integration Complex  Nuclear Entry  Capsid  Sjp-l-5