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Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 4696
Authors:  Hu,Jiadong;  Qiu,Shi;  Wang,Feiyan;  Li,Qing;  Xiang,Chun-Lei;  Di,Peng;  Wu,Ziding;  Jiang,Rui;  Li,Jinxing;  Zeng,Zhen;  Wang,Jing;  Wang,Xingxing;  Zhang,Yuchen;  Fang,Shiyuan;  Qiao,Yuqi;  Ding,Jie;  Jiang,Yun;  Xu,Zhichao;  Chen,Junfeng;  Chen,Wansheng
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CARNOSIC ACID  PHYLOGENETIC ANALYSIS  ARABIDOPSIS-THALIANA  GENOME DUPLICATIONS  STAMINAL EVOLUTION  LAMIACEAE  BIOSYNTHESIS  TANSHINONES  TOOL  
Dirigent gene editing of gossypol enantiomers for toxicity-depleted cotton seeds 期刊论文
NATURE PLANTS, 2023, 卷号: 9, 期号: 4, 页码: 605-+
Authors:  Lin,Jia-Ling;  Fang,Xin;  Li,Jian-Xu;  Chen,Zhi-Wen;  Wu,Wen-Kai;  Guo,Xiao-Xiang;  Liu,Ning-Jing;  Huang,Jia-Fa;  Chen,Fang-Yan;  Wang,Ling-Jian;  Xu,Baofu;  Martin,Cathie;  Chen,Xiao-Ya;  Huang,Jin-Quan
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DOMAIN-CONTAINING PROTEIN  BIOSYNTHESIS  (-)-GOSSYPOL  SYNTHASE  (+)-GOSSYPOL  METABOLISM  EXPRESSION  REDUCTION  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
Favorite  |  View/Download:133/0  |  Submit date:2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids 期刊论文
PLANT PHYSIOLOGY, 2022, 卷号: 188, 期号: 3, 页码: 1496-1506
Authors:  Song,Jiao-Jiao;  Fang,Xin;  Li,Chen-Yi;  Jiang,Yan;  Li,Jian-Xu;  Wu,Sheng;  Guo,Juan;  Liu,Yan;  Fan,Hang;  Huang,Yan-Bo;  Wei,Yu-Kun;  Kong,Yu;  Zhao,Qing;  Xu,Jing-Jing;  Hu,Yong-Hong;  Chen,Xiao-Ya;  Yang,Lei
Favorite  |  View/Download:106/0  |  Submit date:2022/04/02
MOLECULAR-CLONING  BIOSYNTHESIS  TANSHINONES  EVOLUTION  CYTOTOXICITY  SUPERFAMILY  OXYGENASES  APOPTOSIS  SYNTHASE  
Catalytic innovation underlies independent recruitment of polyketide synthases in cocaine and hyoscyamine biosynthesis 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 4994
Authors:  Tian, Tian;  Wang, Yong-Jiang;  Huang, Jian-Ping;  Li, Jie;  Xu, Bingyan;  Chen, Yin;  Wang, Li;  Yang, Jing;  Yan, Yijun;  Huang, Sheng-Xiong
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TROPANE ALKALOID BIOSYNTHESIS  CHAIN-LENGTH CONTROL  
Tsaokols A and B, unusual flavanol-monoterpenoid hybrids as alpha-glucosidase inhibitors from Amomum tsao-ko 期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 3, 页码: 1202-1205
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
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Amomum tsao-ko  Zingiberaceae  Flavanol-monoterpenoid hybrids  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  CREVOST  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
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Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
Authors:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
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PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
Authors:  Wang,Gan;  Yang,Meng-Li;  Duan,Zi-Lei;  Liu,Feng-Liang;  Jin,Lin;  Long,Cheng-Bo;  Zhang,Min;  Tang,Xiao-Peng;  Xu,Ling;  Li,Ying-Chang;  Kamau,Peter Muiruri;  Yang,Lian;  Liu,Hong-Qi;  Xu,Jing-Wen;  Chen,Jie-Kai;  Zheng,Yong-Tang;  Peng,Xiao-Zhong;  Lai,Ren
Favorite  |  View/Download:90/0  |  Submit date:2022/04/02
SARS  ENTRY  MERS  
Large-Scale Characterization of the Soil Microbiome in Ancient Tea Plantations Using High-Throughput 16S rRNA and Internal Transcribed Spacer Amplicon Sequencing 期刊论文
FRONTIERS IN MICROBIOLOGY, 2021, 卷号: 12, 页码: 745225
Authors:  Kui,Ling;  Xiang,Guisheng;  Wang,Ya;  Wang,Zijun;  Li,Guorong;  Li,Dawei;  Yan,Jing;  Ye,Shuang;  Wang,Chunping;  Yang,Ling;  Zhang,Shiyu;  Zhang,Shuangyan;  Zhou,Ling;  Gui,Heng;  Xu,Jianchu;  Chen,Wei;  Zhang,Jun;  Huang,Tingyuan;  Majeed,Aasim;  Sheng,Jun;  Dong,Yang
Adobe PDF(11467Kb)  |  Favorite  |  View/Download:94/11  |  Submit date:2022/04/02
Camellia sinensis var  assamica  microbiome  function  ancient tea plantations  16S and ITS rRNA  FUNGAL COMMUNITIES  CAMELLIA-SINENSIS  BACTERIAL COMMUNITIES  ALTITUDINAL GRADIENT  ORCHARD SOILS  ACIDIFICATION  RHIZOSPHERE  DIVERSITY  GROWTH  NITROGEN