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基于酚酸类结构研究抗流感病毒、 新冠病毒前体药物 学位论文
: 中国科学院大学, 2022
作者:  侯博
Adobe PDF(7912Kb)  |  收藏  |  浏览/下载：146/0  |  提交时间：2024/05/14
乙酰化酚酸环， 流感病毒， 新冠病毒， 抑制剂  Acetylflicinic acid cycle, Flu virus, SARS-CoV-2, Inhibitors  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：264/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Prevalence of molecular and serological tests of the new coronavirus (SARS-CoV-2) in Carlos Chagas laboratory - Sabin group in Cuiaba 期刊论文
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2022, 卷号: 68, 期号: 3, 页码: 344-350
作者:  de Paula, Cristiane Coimbra;  Shimoya-Bittencourt, Walkiria;  Passos, Joao Pedro Castoldo;  Paula, Caroline Aquino Vieira De Lamare;  Arunachalam, Karuppusamy;  Fontes, Cor Jesus Fernandes;  de Oliveira, Ruberlei Godinho
Adobe PDF(326Kb)  |  收藏  |  浏览/下载：172/39  |  提交时间：2024/04/30
Coronavirus  Reverse Transcriptase PCR  Serology  Immunoglobulin G  Immunoglobulin M  
菲啶类抗PEDV与SARS-CoV-2的活性化合物设计与作用机制研究 学位论文
, 2021
作者:  王宜挺
Adobe PDF(7827Kb)  |  收藏  |  浏览/下载：70/0  |  提交时间：2024/03/20
Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 1, 页码: 127-135
作者:  Zhao,Yun-Li;  Gou,Zhong-Ping;  Shang,Jian-Hua;  Li,Wan-Yi;  Kuang,Yu;  Li,Ming-Yuan;  Luo,Xiao-Dong
Adobe PDF(958Kb)  |  收藏  |  浏览/下载：233/72  |  提交时间：2022/04/02
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
作者:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
Adobe PDF(8772Kb)  |  收藏  |  浏览/下载：338/67  |  提交时间：2022/04/02
PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
作者:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
浏览  |  Adobe PDF(523Kb)  |  收藏  |  浏览/下载：211/39  |  提交时间：2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
作者:  Guo,Sheng;  Xie,Hang;  Lei,Yu;  Liu,Bin;  Zhang,Li;  Xu,Yechun;  Zuo,Zhili
浏览  |  Adobe PDF(3181Kb)  |  收藏  |  浏览/下载：283/65  |  提交时间：2022/04/02
SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation  
Which species does the virus like most: Binding modes study between SARS-CoV-2 S protein and ACE2 receptor 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2021, 卷号: 105, 页码: 107893
作者:  Guo,Sheng;  Yang,Jing;  Lei,Yu;  Liu,Bin;  Zhang,Wei;  Zhang,Li;  Zuo,Zhili
浏览  |  Adobe PDF(3681Kb)  |  收藏  |  浏览/下载：228/31  |  提交时间：2022/04/02
SARS-CoV-2  COVID-19  Homology modeling  Molecular dynamics simulation  Binding free energy  CORONAVIRUS SPIKE PROTEIN  ACTIVATION  GROMACS  ENTRY  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
作者:  Wang,Gan;  Yang,Meng-Li;  Duan,Zi-Lei;  Liu,Feng-Liang;  Jin,Lin;  Long,Cheng-Bo;  Zhang,Min;  Tang,Xiao-Peng;  Xu,Ling;  Li,Ying-Chang;  Kamau,Peter Muiruri;  Yang,Lian;  Liu,Hong-Qi;  Xu,Jing-Wen;  Chen,Jie-Kai;  Zheng,Yong-Tang;  Peng,Xiao-Zhong;  Lai,Ren
收藏  |  浏览/下载：227/0  |  提交时间：2022/04/02
SARS  ENTRY  MERS