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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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基于酚酸类结构研究抗流感病毒、 新冠病毒前体药物
学位论文
: 中国科学院大学, 2022
Authors:
侯博
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Submit date:2024/05/14
乙酰化酚酸环, 流感病毒, 新冠病毒, 抑制剂
Acetylflicinic acid cycle, Flu virus, SARS-CoV-2, Inhibitors
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:
Wang,Yi-Ting
;
Long,Xin-Yan
;
Ding,Xiao
;
Fan,Shi-Rui
;
Cai,Jie-Yun
;
Yang,Bi-Juan
;
Zhang,Xin-Fang
;
Luo,Rong-hua
;
Yang,Lian
;
Ruan,Ting
;
Ren,Juan
;
Jing,Chen-Xu
;
Zheng,Yong-Tang
;
Hao,Xiao-Jiang
;
Chen,Duo-Zhi
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Submit date:2022/04/02
Phenanthridine
Nucleocapsid protein
SARS-CoV-2
N-terminal domain
N-TERMINAL DOMAIN
CORONAVIRUS
Prevalence of molecular and serological tests of the new coronavirus (SARS-CoV-2) in Carlos Chagas laboratory - Sabin group in Cuiaba
期刊论文
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2022, 卷号: 68, 期号: 3, 页码: 344-350
Authors:
de Paula, Cristiane Coimbra
;
Shimoya-Bittencourt, Walkiria
;
Passos, Joao Pedro Castoldo
;
Paula, Caroline Aquino Vieira De Lamare
;
Arunachalam, Karuppusamy
;
Fontes, Cor Jesus Fernandes
;
de Oliveira, Ruberlei Godinho
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Submit date:2024/04/30
Coronavirus
Reverse Transcriptase PCR
Serology
Immunoglobulin G
Immunoglobulin M
菲啶类抗PEDV与SARS-CoV-2的活性化合物设计与作用机制研究
学位论文
, 2021
Authors:
王宜挺
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Submit date:2024/03/20
Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris
期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 1, 页码: 127-135
Authors:
Zhao,Yun-Li
;
Gou,Zhong-Ping
;
Shang,Jian-Hua
;
Li,Wan-Yi
;
Kuang,Yu
;
Li,Ming-Yuan
;
Luo,Xiao-Dong
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Submit date:2022/04/02
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
Authors:
Chen,Duo-Zhi
;
Fan,Shi-Rui
;
Yang,Bi-Juan
;
Yao,Huo-Chun
;
Wang,Yi-Ting
;
Cai,Jie-Yun
;
Jing,Chen-Xu
;
Pan,Zi-Hao
;
Luo,Miao
;
Yuze,Yan-Qiu
;
Liu,Guang-Jin
;
Hao,Xiao-Jiang
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Submit date:2022/04/02
PROTEIN
CORONAVIRUSES
SARS
PARTICLES
INSIGHTS
HSC70
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
Authors:
Munikishore,Rachakunta
;
Wang,Liang-Liang
;
Zhang,Shuqun
;
Zhao,Qin-Shi
;
Zuo,Zhili
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Submit date:2022/04/02
Cathepsin L
small-molecule inhibitor
gram-scale synthesis
KGP94
cancer
FUNCTIONALIZED BENZOPHENONE
BIOLOGICAL EVALUATION
TUMOR PROGRESSION
CELL INVASION
EXPRESSION
ANALOGS
SUPPRESSION
DERIVATIVES
ACID
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
Authors:
Guo,Sheng
;
Xie,Hang
;
Lei,Yu
;
Liu,Bin
;
Zhang,Li
;
Xu,Yechun
;
Zuo,Zhili
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Submit date:2022/04/02
SARS-CoV-2
Main protease
Virtual screening
Biochemical evaluation
Which species does the virus like most: Binding modes study between SARS-CoV-2 S protein and ACE2 receptor
期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2021, 卷号: 105, 页码: 107893
Authors:
Guo,Sheng
;
Yang,Jing
;
Lei,Yu
;
Liu,Bin
;
Zhang,Wei
;
Zhang,Li
;
Zuo,Zhili
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Submit date:2022/04/02
SARS-CoV-2
COVID-19
Homology modeling
Molecular dynamics simulation
Binding free energy
CORONAVIRUS SPIKE PROTEIN
ACTIVATION
GROMACS
ENTRY
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models
期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
Authors:
Wang,Gan
;
Yang,Meng-Li
;
Duan,Zi-Lei
;
Liu,Feng-Liang
;
Jin,Lin
;
Long,Cheng-Bo
;
Zhang,Min
;
Tang,Xiao-Peng
;
Xu,Ling
;
Li,Ying-Chang
;
Kamau,Peter Muiruri
;
Yang,Lian
;
Liu,Hong-Qi
;
Xu,Jing-Wen
;
Chen,Jie-Kai
;
Zheng,Yong-Tang
;
Peng,Xiao-Zhong
;
Lai,Ren
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Submit date:2022/04/02
SARS
ENTRY
MERS