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Pharmacology and anti-addiction effects of the novel kappa opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A 期刊论文
出版物, 3111, 期号: 0, 页码: 1-53
Authors:  B Simonson;  A S Morani;  A W M Ewald;  L Walker;  N Kumar;  D Simpson;  J H Miller;  T E Prisinzano;  B M Kivell
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Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
Authors:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
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A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids 期刊论文
PLANT PHYSIOLOGY, 2022, 卷号: 188, 期号: 3, 页码: 1496-1506
Authors:  Song,Jiao-Jiao;  Fang,Xin;  Li,Chen-Yi;  Jiang,Yan;  Li,Jian-Xu;  Wu,Sheng;  Guo,Juan;  Liu,Yan;  Fan,Hang;  Huang,Yan-Bo;  Wei,Yu-Kun;  Kong,Yu;  Zhao,Qing;  Xu,Jing-Jing;  Hu,Yong-Hong;  Chen,Xiao-Ya;  Yang,Lei
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MOLECULAR-CLONING  BIOSYNTHESIS  TANSHINONES  EVOLUTION  CYTOTOXICITY  SUPERFAMILY  OXYGENASES  APOPTOSIS  SYNTHASE  
seco-Prezizanne Sesquiterpenes and Prenylated C6-C3 Compounds from the Fruits of Illicium lanceolatum A. C. Smith 期刊论文
CHEMISTRY & BIODIVERSITY, 2022, 卷号: 19, 期号: 1, 页码: e202100868
Authors:  Nie,Wei;  Ding,Lin-Fen;  Tie-Lei;  Zhou,Hao-Feng;  Bao,Yi;  Song,Liu-Dong;  Pan,Zheng-Hong;  Wu,Xing-De;  Zhao,Qin-Shi
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Illicium lanceolatum A  C  Smith  seco-prezizanne sesquiterpene  prenylated C6-C3 compound  neuroprotective activity  NEUROTROPHIC ACTIVITY  C-6-C-3 COMPOUNDS  STEM BARK  ROOTS  SKELETON  
Synthesis and Antitumor Activity of 1-Substituted 1,2,3-Triazole-Mollugin Derivatives 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 11, 页码: 3249
Authors:  Luo,Han;  Lv,Yong-Feng;  Zhang,Hong;  Hu,Jiang-Miao;  Li,Hong-Mei;  Liu,Shou-Jin
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mollugin  triazoles  antitumor activity  synthesis  ANTIMICROBIAL ACTIVITY  RUBIA-CORDIFOLIA  MOLLUGIN  DESIGN  ANALOGS  BIOEVALUATION  GLYCOSIDES  APOPTOSIS  AZIDES  
Polycyclic polyprenylated acylphloroglucinol derivatives with neuroprotective effects from Hypericum monogynum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 卷号: 23, 期号: 1, 页码: 73-81
Authors:  Zeng,Yan-Rong;  Li,Ya-Na;  Lou,Hua-Yong;  Jian,Jun-You;  Gu,Wei;  Huang,Lie-Jun;  Du,Guan-Hua;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
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Hypericum monogynum  polycyclic polyprenylated acylphloroglucinols (PPAPs)  neuroprotective effects  structure-activity relationship  ST JOHNS WORT  PHLOROGLUCINOL DERIVATIVES  PRENYLATED PHLOROGLUCINOL  HYPERFORIN  ANALOGS  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Biosynthetically Inspired Divergent Syntheses of Merocytochalasans 期刊论文
CHEM, 2021, 卷号: 7, 期号: 1, 页码: 212-223
Authors:  Long,Xianwen;  Wu,Hai;  Ding,Yiming;  Qu,Chunlei;  Deng,Jun
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RING-SYSTEM  REARRANGEMENTS  DIMER  
Discovery and heterologous production of sarubicins and quinazolinone C-glycosides with protecting activity for cardiomyocytes 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2021, 卷号: 8, 期号: 14, 页码: 3829-3837
Authors:  Yu,Mingming;  Luo,Jianying;  Luo,Dan;  He,Qiang;  Yan,Yijun;  Ji,Xu;  Huang,Sheng-Xiong
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STREPTOMYCES-VIOLACEORUBER TU22  BIOSYNTHESIS  GRANATICIN  ANTIBIOTICS  METABOLISM  MECHANISM  PATHWAY  ACID  
Structure Revision of Four Classes of Prenylated Aromatic Natural Products Based on a Rule for Diagnostic C-13 NMR Chemical Shifts 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 16, 页码: 10982-10990
Authors:  Ren,Fu-Cai;  Wang,Li-Xia;  Lv,Yong-Feng;  Hu,Jiang-Miao;  Zhou,Jun
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ISOPRENYLATED FLAVONOIDS  CONSTITUENTS  DERIVATIVES  ANALOGS