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Pharmacology and anti-addiction effects of the novel kappa opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A 期刊论文
出版物, 3111, 期号: 0, 页码: 1-53
作者:  B Simonson;  A S Morani;  A W M Ewald;  L Walker;  N Kumar;  D Simpson;  J H Miller;  T E Prisinzano;  B M Kivell
Adobe PDF(1394Kb)  |  收藏  |  浏览/下载:496/1  |  提交时间:2017/07/24
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
作者:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
Adobe PDF(425Kb)  |  收藏  |  浏览/下载:256/1  |  提交时间:2017/07/21
Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
浏览  |  Adobe PDF(5670Kb)  |  收藏  |  浏览/下载:221/41  |  提交时间:2024/07/17
Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Three New Selaginellin Derivatives from Selaginella pulvinata and Their alpha-Glucosidase Inhibitory Activity 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
作者:  Zhu,Qin-Feng;  Luo,Tian-Tian;  Chen,Qian;  Gao,Bei-Bei;  Zeng,Ai-Fen;  Ao,Jun-Li;  Xu,Guo-Bo;  Liao,Shang-Gao;  He,Xun
浏览  |  Adobe PDF(1034Kb)  |  收藏  |  浏览/下载:186/54  |  提交时间:2024/07/10
Selaginella pulvinata  selaginellin  selaginpulvilins V-X  alpha-glucosidase inhibitory activity  TAMARISCINA  MECHANISM  
Three New Selaginellin Derivatives from Selaginella pulvinata and Their α-Glucosidase Inhibitory Activity 期刊论文
CHEMISTRY & BIODIVERSITY, 2023, 卷号: 20, 期号: 4
作者:  Zhu,Qin-Feng;  Luo,Tian-Tian;  Chen,Qian;  Gao,Bei-Bei;  Zeng,Ai-Fen;  Ao,Jun-Li;  Xu,Guo-Bo;  Liao,Shang-Gao;  He,Xun
浏览  |  Adobe PDF(1034Kb)  |  收藏  |  浏览/下载:179/55  |  提交时间:2024/07/10
Selaginella pulvinata  selaginellin  selaginpulvilins V-X  alpha-glucosidase inhibitory activity  TAMARISCINA  MECHANISM  
Design, synthesis, and biological evaluation of artemyrianolide H derivatives as potential antihepatoma agents 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 106617
作者:  Li,Tian-Ze;  Yang,Xiao-Tong;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Wang,Yong-Cui;  Chen,Ji-Jun
浏览  |  Adobe PDF(9670Kb)  |  收藏  |  浏览/下载:194/47  |  提交时间:2024/07/22
Artemyrianolide H  Germacranolide derivatives  Antihepatoma activity  Apoptosis  DIMERS  
Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 210, 页码: 113642
作者:  Liu,Jie;  Yan,Qin;  Wang,Li-Xia;  He,Xiao-Ping;  Hu,Hong;  Liu,Yan-Chun;  Li,Dan;  Liu,Yan;  Guo,Kai;  Li,Sheng-Hong
浏览  |  Adobe PDF(643Kb)  |  收藏  |  浏览/下载:197/49  |  提交时间:2024/07/22
Swertia pseudochinensis Hara  Gentianaceae  Secoiridoids  Anti-inflammatory activity  NATURALLY-OCCURRING IRIDOIDS  CHEMICAL-CONSTITUENTS  PART  BIOTRANSFORMATION  GENTIOPICROSIDE  BIOSYNTHESIS  GLUCOSIDES  
NMR-tracking for 15,16-seco-cycloartane triterpenes from Cimicifuga acerina 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 210, 页码: 113669
作者:  Lin,Liwu;  Zhou,Haoran;  Wen,Luan;  Al-Romaima,Abdulbaset;  Peng,Xingrong;  Qiu,Minghua
Adobe PDF(4755Kb)  |  收藏  |  浏览/下载:206/42  |  提交时间:2024/07/25
Cimicifuga acerina  Ranunculaceae  15  16-seco-cycloartane triterpenoids  NMR-Tracking  ACETYL SHENGMANOL  AERIAL PARTS  GLYCOSIDES  CONSTITUENTS  YUNNANENSIS  RACEMOSA  SAPONINS  RHIZOMA  PLANTS  
Structurally diverse spirocyclic polycyclic polyprenylated acylphloroglucinols from Hypericum ascyron Linn. and their anti-tumor activity 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 212, 页码: 113727
作者:  Hu,Ya-Li;  Yue,Grace Gar-Lee;  Li,Xing-Ren;  Xu,Gang;  Lau,Clara Bik-San
Adobe PDF(6872Kb)  |  收藏  |  浏览/下载:149/32  |  提交时间:2024/07/25
Hypericaceae  Polycyclic polyprenylated acylphloroglucinols  Spirocyclic polyprenylated acylphloroglucinols  HCT116 cells  Zebrafish model  Hypericum ascyron Linn  NATURAL-PRODUCTS  A-H  DERIVATIVES  FLOWERS  VEGF  
The Aqueous Extract of Brassica oleracea L. Exerts Phytotoxicity by Modulating H2O2 and O2Levels, Antioxidant Enzyme Activity and Phytohormone Levels 期刊论文
PLANTS-BASEL, 2023, 卷号: 12, 期号: 17, 页码: 3086
作者:  Wang,Yu;  Zhao,Yuanzheng;  Dong,Baozhu;  Wang,Dong;  Hao,Jianxiu;  Jia,Xinyu;  Zhao,Yuxi;  Nian,Yin;  Zhou,Hongyou
Adobe PDF(6434Kb)  |  收藏  |  浏览/下载:247/29  |  提交时间:2024/05/09
allelopathy  reactive oxygen species  antioxidant enzymes  phytohormones  LC-MS  AUXIN  ESTER