Three New Selaginellin Derivatives from Selaginella pulvinata and Their alpha-Glucosidase Inhibitory Activity

doi:10.1002/cbdv.202300109

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	Three New Selaginellin Derivatives from Selaginella pulvinata and Their alpha-Glucosidase Inhibitory Activity
	Zhu,Qin-Feng; Luo,Tian-Tian; Chen,Qian; Gao,Bei-Bei; Zeng,Ai-Fen; Ao,Jun-Li; Xu,Guo-Bo; Liao,Shang-Gao; He,Xun
	2023
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1880
摘要	Three new selaginellin derivatives, selaginpulvilins V-X (1-3), together with seven known analogs (4-10) were isolated from whole plants of Selaginella pulvinata. Their structures were determined by extensive spectroscopic methods including 1D and 2D NMR, HR-ESI-MS and chemical derivatization method. Compound 1 represents a rare example of naturally occurring selaginellin with an alkynylphenol-trimmed skeleton. Biological evaluation showed that compounds 2, 6 and 8 displayed moderate inhibition against alpha-glucosidase with IC50 values of 3.71, 2.04 and 4.00 mu M, respectively.
关键词	Selaginella pulvinata selaginellin selaginpulvilins V-X alpha-glucosidase inhibitory activity TAMARISCINA MECHANISM
学科领域	Biochemistry & Molecular Biology ; Chemistry
DOI	10.1002/cbdv.202300109
收录类别	SCI
WOS记录号	WOS:000939706500001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75328
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhu,Qin-Feng,Luo,Tian-Tian,Chen,Qian,et al. Three New Selaginellin Derivatives from Selaginella pulvinata and Their alpha-Glucosidase Inhibitory Activity[J]. CHEMISTRY & BIODIVERSITY,2023.
APA	Zhu,Qin-Feng.,Luo,Tian-Tian.,Chen,Qian.,Gao,Bei-Bei.,Zeng,Ai-Fen.,...&He,Xun.(2023).Three New Selaginellin Derivatives from Selaginella pulvinata and Their alpha-Glucosidase Inhibitory Activity.CHEMISTRY & BIODIVERSITY.
MLA	Zhu,Qin-Feng,et al."Three New Selaginellin Derivatives from Selaginella pulvinata and Their alpha-Glucosidase Inhibitory Activity".CHEMISTRY & BIODIVERSITY (2023).

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