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Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis
Liu,Jie; Yan,Qin; Wang,Li-Xia; He,Xiao-Ping; Hu,Hong; Liu,Yan-Chun; Li,Dan; Liu,Yan; Guo,Kai; Li,Sheng-Hong
2023
Source PublicationPHYTOCHEMISTRY
ISSN1873-3700
Volume210Pages:113642
AbstractDetailed phytochemical investigation on the traditional Chinese medicine Swertia pseudochinensis Hara led to the isolation of ten undescribed secoiridoids and fifteen known analogs. Their structures were elucidated by extensive spectroscopic analysis (including 1D and 2D NMR, and HRESIMS). Selected isolates were assayed for their anti-inflammatory and antibacterial activities, and moderate anti-inflammatory activity via inhibiting the secretion of cytokines IL-6 and TNF-alpha in macrophages RAW264.7 induced by LPS were observed. Antibacterial activity against Staphylococcus aureus was not found at 100 mu M.
KeywordSwertia pseudochinensis Hara Gentianaceae Secoiridoids Anti-inflammatory activity NATURALLY-OCCURRING IRIDOIDS CHEMICAL-CONSTITUENTS PART BIOTRANSFORMATION GENTIOPICROSIDE BIOSYNTHESIS GLUCOSIDES
Subject AreaBiochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytochem.2023.113642
Indexed BySCI
WOS IDWOS:000967953200001
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Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/75430
Collection中国科学院昆明植物研究所
Recommended Citation
GB/T 7714
Liu,Jie,Yan,Qin,Wang,Li-Xia,et al. Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis[J]. PHYTOCHEMISTRY,2023,210:113642.
APA Liu,Jie.,Yan,Qin.,Wang,Li-Xia.,He,Xiao-Ping.,Hu,Hong.,...&Li,Sheng-Hong.(2023).Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis.PHYTOCHEMISTRY,210,113642.
MLA Liu,Jie,et al."Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis".PHYTOCHEMISTRY 210(2023):113642.
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