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| Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis | |
Liu,Jie ; Yan,Qin; Wang,Li-Xia; He,Xiao-Ping; Hu,Hong; Liu,Yan-Chun; Li,Dan; Liu,Yan; Guo,Kai; Li,Sheng-Hong
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| 2023 | |
| Source Publication | PHYTOCHEMISTRY
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| ISSN | 1873-3700 |
| Volume | 210Pages:113642 |
| Abstract | Detailed phytochemical investigation on the traditional Chinese medicine Swertia pseudochinensis Hara led to the isolation of ten undescribed secoiridoids and fifteen known analogs. Their structures were elucidated by extensive spectroscopic analysis (including 1D and 2D NMR, and HRESIMS). Selected isolates were assayed for their anti-inflammatory and antibacterial activities, and moderate anti-inflammatory activity via inhibiting the secretion of cytokines IL-6 and TNF-alpha in macrophages RAW264.7 induced by LPS were observed. Antibacterial activity against Staphylococcus aureus was not found at 100 mu M. |
| Keyword | Swertia pseudochinensis Hara Gentianaceae Secoiridoids Anti-inflammatory activity NATURALLY-OCCURRING IRIDOIDS CHEMICAL-CONSTITUENTS PART BIOTRANSFORMATION GENTIOPICROSIDE BIOSYNTHESIS GLUCOSIDES |
| Subject Area | Biochemistry & Molecular Biology ; Plant Sciences |
| DOI | 10.1016/j.phytochem.2023.113642 |
| Indexed By | SCI |
| WOS ID | WOS:000967953200001 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/75430 |
| Collection | 中国科学院昆明植物研究所 |
| Recommended Citation GB/T 7714 | Liu,Jie,Yan,Qin,Wang,Li-Xia,et al. Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis[J]. PHYTOCHEMISTRY,2023,210:113642. |
| APA | Liu,Jie.,Yan,Qin.,Wang,Li-Xia.,He,Xiao-Ping.,Hu,Hong.,...&Li,Sheng-Hong.(2023).Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis.PHYTOCHEMISTRY,210,113642. |
| MLA | Liu,Jie,et al."Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis".PHYTOCHEMISTRY 210(2023):113642. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S003194222300（643KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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