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Characterization and protein engineering of glycosyltransferases for the biosynthesis of diverse hepatoprotective cycloartane-type saponins in Astragalus membranaceus 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2023
Authors:  Chen,Kuan;  Zhang,Meng;  Gao,Baihan;  Hasan,Aobulikasimu;  Li,Junhao;  Bao,Yang'oujie;  Fan,Jingjing;  Yu,Rong;  Yi,Yang;  Agren,Hans;  Wang,Zilong;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
View  |  Adobe PDF(5002Kb)  |  Favorite  |  View/Download：133/26  |  Submit date：2024/05/09
astragalosides  biosynthesis  glycosyltransferases  protein engineering  Astragalus membranaceus  FUNCTIONAL-CHARACTERIZATION  UDP-GLYCOSYLTRANSFERASES  CARBON-TETRACHLORIDE  PROTOPANAXATRIOL  PHARMACOLOGY  GENERATION  CHEMISTRY  ACCURACY  PATHWAY  
基于酚酸类结构研究抗流感病毒、 新冠病毒前体药物 学位论文
: 中国科学院大学, 2022
Authors:  侯博
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乙酰化酚酸环， 流感病毒， 新冠病毒， 抑制剂  Acetylflicinic acid cycle, Flu virus, SARS-CoV-2, Inhibitors  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
Favorite  |  View/Download：184/0  |  Submit date：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Prevalence of molecular and serological tests of the new coronavirus (SARS-CoV-2) in Carlos Chagas laboratory - Sabin group in Cuiaba 期刊论文
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2022, 卷号: 68, 期号: 3, 页码: 344-350
Authors:  de Paula, Cristiane Coimbra;  Shimoya-Bittencourt, Walkiria;  Passos, Joao Pedro Castoldo;  Paula, Caroline Aquino Vieira De Lamare;  Arunachalam, Karuppusamy;  Fontes, Cor Jesus Fernandes;  de Oliveira, Ruberlei Godinho
View  |  Adobe PDF(326Kb)  |  Favorite  |  View/Download：63/9  |  Submit date：2024/04/30
Coronavirus  Reverse Transcriptase PCR  Serology  Immunoglobulin G  Immunoglobulin M  
A new polysaccharide platform constructs self-adjuvant nanovaccines to enhance immune responses 期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2022, 卷号: 20, 期号: 1, 页码: 320
Authors:  Chen, Sisi;  Yang, Liu;  Ou, Xia;  Li, Jin-Yu;  Zi, Cheng-Ting;  Wang, Hao;  Hu, Jiang-Miao;  Liu, Ye
View  |  Adobe PDF(7638Kb)  |  Favorite  |  View/Download：62/15  |  Submit date：2024/04/30
Polysaccharide  Self-adjuvant  Nanovaccine  SARS-CoV-2  HIV  STRUCTURAL-CHARACTERIZATION  DENDRITIC CELLS  DRUG-DELIVERY  NANOPARTICLES  PARTICLES  CHITOSAN  GLYCOGEN  DESIGN  
四种高含量天然产物的化学及生物功能研究 学位论文
, 2021
Authors:  周元飞
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菲啶类抗PEDV与SARS-CoV-2的活性化合物设计与作用机制研究 学位论文
, 2021
Authors:  王宜挺
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AmAT19, an acetyltransferase from Astragalus membranaceus, catalyses specific 6 alpha-OH acetylation for tetracyclic triterpenes and steroids 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 33, 页码: 7186-7189
Authors:  Wang,Linlin;  Chen,Kuan;  Wang,Zilong;  Yi,Yang;  Zhang,Meng;  Hasan,Aobulikasimu;  Kuang,Yi;  Shaker,Sharpkate;  Yu,Rong;  Wang,Haotian;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
Favorite  |  View/Download：110/0  |  Submit date：2022/04/02
ACYLATION  ACYLTRANSFERASE  CYCLOASTRAGENOL  BAHD  
1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 30, 页码: 6650-6656
Authors:  Huang,Jin-Quan;  Li,Dong-Mei;  Li,Jian-Xu;  Lin,Jia-Ling;  Tian,Xiu;  Wang,Ling-Jian;  Chen,Xiao-Ya;  Fang,Xin
View  |  Adobe PDF(2357Kb)  |  Favorite  |  View/Download：130/21  |  Submit date：2022/04/02
ACTIVE-SITE RESIDUES  ARISTOLOCHENE SYNTHASE  ARTEMISIA-ANNUA  BIOLOGY  IDENTIFICATION  BIOSYNTHESIS  EXPRESSION  CLONING  GENES  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
Authors:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
View  |  Adobe PDF(523Kb)  |  Favorite  |  View/Download：139/32  |  Submit date：2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID