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Characterization and protein engineering of glycosyltransferases for the biosynthesis of diverse hepatoprotective cycloartane-type saponins in Astragalus membranaceus 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2023
作者:  Chen,Kuan;  Zhang,Meng;  Gao,Baihan;  Hasan,Aobulikasimu;  Li,Junhao;  Bao,Yang'oujie;  Fan,Jingjing;  Yu,Rong;  Yi,Yang;  Agren,Hans;  Wang,Zilong;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
浏览  |  Adobe PDF(5002Kb)  |  收藏  |  浏览/下载：49/10  |  提交时间：2024/05/09
astragalosides  biosynthesis  glycosyltransferases  protein engineering  Astragalus membranaceus  FUNCTIONAL-CHARACTERIZATION  UDP-GLYCOSYLTRANSFERASES  CARBON-TETRACHLORIDE  PROTOPANAXATRIOL  PHARMACOLOGY  GENERATION  CHEMISTRY  ACCURACY  PATHWAY  
基于酚酸类结构研究抗流感病毒、 新冠病毒前体药物 学位论文
: 中国科学院大学, 2022
作者:  侯博
Adobe PDF(7912Kb)  |  收藏  |  浏览/下载：16/0  |  提交时间：2024/05/14
乙酰化酚酸环， 流感病毒， 新冠病毒， 抑制剂  Acetylflicinic acid cycle, Flu virus, SARS-CoV-2, Inhibitors  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：133/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Prevalence of molecular and serological tests of the new coronavirus (SARS-CoV-2) in Carlos Chagas laboratory - Sabin group in Cuiaba 期刊论文
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2022, 卷号: 68, 期号: 3, 页码: 344-350
作者:  de Paula, Cristiane Coimbra;  Shimoya-Bittencourt, Walkiria;  Passos, Joao Pedro Castoldo;  Paula, Caroline Aquino Vieira De Lamare;  Arunachalam, Karuppusamy;  Fontes, Cor Jesus Fernandes;  de Oliveira, Ruberlei Godinho
浏览  |  Adobe PDF(326Kb)  |  收藏  |  浏览/下载：21/7  |  提交时间：2024/04/30
Coronavirus  Reverse Transcriptase PCR  Serology  Immunoglobulin G  Immunoglobulin M  
A new polysaccharide platform constructs self-adjuvant nanovaccines to enhance immune responses 期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2022, 卷号: 20, 期号: 1, 页码: 320
作者:  Chen, Sisi;  Yang, Liu;  Ou, Xia;  Li, Jin-Yu;  Zi, Cheng-Ting;  Wang, Hao;  Hu, Jiang-Miao;  Liu, Ye
浏览  |  Adobe PDF(7638Kb)  |  收藏  |  浏览/下载：26/9  |  提交时间：2024/04/30
Polysaccharide  Self-adjuvant  Nanovaccine  SARS-CoV-2  HIV  STRUCTURAL-CHARACTERIZATION  DENDRITIC CELLS  DRUG-DELIVERY  NANOPARTICLES  PARTICLES  CHITOSAN  GLYCOGEN  DESIGN  
Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 11, 页码: 2045-2057
作者:  Li, Tian-Ze;  Huang, Xiao-Yan;  Sun, Jin-Jin;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1234Kb)  |  收藏  |  浏览/下载：39/9  |  提交时间：2024/04/30
(+)-Paeoveitol derivatives  Antidepressant  Forced swimming test  Monoamine neurotransmitter  
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：39/9  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
四种高含量天然产物的化学及生物功能研究 学位论文
, 2021
作者:  周元飞
Adobe PDF(13409Kb)  |  收藏  |  浏览/下载：22/0  |  提交时间：2024/03/20
菲啶类抗PEDV与SARS-CoV-2的活性化合物设计与作用机制研究 学位论文
, 2021
作者:  王宜挺
Adobe PDF(7827Kb)  |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/20
AmAT19, an acetyltransferase from Astragalus membranaceus, catalyses specific 6 alpha-OH acetylation for tetracyclic triterpenes and steroids 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 33, 页码: 7186-7189
作者:  Wang,Linlin;  Chen,Kuan;  Wang,Zilong;  Yi,Yang;  Zhang,Meng;  Hasan,Aobulikasimu;  Kuang,Yi;  Shaker,Sharpkate;  Yu,Rong;  Wang,Haotian;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
收藏  |  浏览/下载：78/0  |  提交时间：2022/04/02
ACYLATION  ACYLTRANSFERASE  CYCLOASTRAGENOL  BAHD