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Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
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Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
Authors:  Wang,Gan;  Yang,Meng-Li;  Duan,Zi-Lei;  Liu,Feng-Liang;  Jin,Lin;  Long,Cheng-Bo;  Zhang,Min;  Tang,Xiao-Peng;  Xu,Ling;  Li,Ying-Chang;  Kamau,Peter Muiruri;  Yang,Lian;  Liu,Hong-Qi;  Xu,Jing-Wen;  Chen,Jie-Kai;  Zheng,Yong-Tang;  Peng,Xiao-Zhong;  Lai,Ren
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SARS  ENTRY  MERS  
Which species does the virus like most: Binding modes study between SARS-CoV-2 S protein and ACE2 receptor 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2021, 卷号: 105, 页码: 107893
Authors:  Guo,Sheng;  Yang,Jing;  Lei,Yu;  Liu,Bin;  Zhang,Wei;  Zhang,Li;  Zuo,Zhili
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SARS-CoV-2  COVID-19  Homology modeling  Molecular dynamics simulation  Binding free energy  CORONAVIRUS SPIKE PROTEIN  ACTIVATION  GROMACS  ENTRY  
1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 30, 页码: 6650-6656
Authors:  Huang,Jin-Quan;  Li,Dong-Mei;  Li,Jian-Xu;  Lin,Jia-Ling;  Tian,Xiu;  Wang,Ling-Jian;  Chen,Xiao-Ya;  Fang,Xin
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ACTIVE-SITE RESIDUES  ARISTOLOCHENE SYNTHASE  ARTEMISIA-ANNUA  BIOLOGY  IDENTIFICATION  BIOSYNTHESIS  EXPRESSION  CLONING  GENES  
AmAT19, an acetyltransferase from Astragalus membranaceus, catalyses specific 6 alpha-OH acetylation for tetracyclic triterpenes and steroids 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 33, 页码: 7186-7189
Authors:  Wang,Linlin;  Chen,Kuan;  Wang,Zilong;  Yi,Yang;  Zhang,Meng;  Hasan,Aobulikasimu;  Kuang,Yi;  Shaker,Sharpkate;  Yu,Rong;  Wang,Haotian;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
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ACYLATION  ACYLTRANSFERASE  CYCLOASTRAGENOL  BAHD  
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
Authors:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
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PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
Authors:  Guo,Sheng;  Xie,Hang;  Lei,Yu;  Liu,Bin;  Zhang,Li;  Xu,Yechun;  Zuo,Zhili
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SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation  
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105314
Authors:  Chen,Jing;  Yu,Yang;  Wu,Jing;  Bao,Mei-Fen;  Kongkiatpaiboon,Sumet;  Schinnerl,Johann;  Cai,Xiang-Hai
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Tabernaemontana divaricata 'Dwaft'  Monoterpenoid indole alkaloid  Aspidosperma-type trimmers  Aspidosperma-type dimers  Cytotoxicity  MONOTERPENOID INDOLE ALKALOIDS  BISINDOLE ALKALOIDS  DIVERSE SKELETONS  A-I  CONOPHYLLINE  
Ecological drivers of tree assemblage in tropical, subtropical and subalpine forests 期刊论文
JOURNAL OF VEGETATION SCIENCE, 2020, 卷号: 31, 期号: 1, 页码: 107-117
Authors:  Asefa,Mengesha;  Wen,Han-Dong;  Brown,Calum;  Cao,Min;  Xu,Kun;  Hu,Yue-Hua
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Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020
Authors:  Zhou, Han;  Peng, Xingrong;  Hou, Tao;  Zhao, Nan;  Qiu, Minghua;  Zhang, Xiuli;  Liang, Xinmiao
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