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Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：100/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
AmAT19, an acetyltransferase from Astragalus membranaceus, catalyses specific 6 alpha-OH acetylation for tetracyclic triterpenes and steroids 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 33, 页码: 7186-7189
作者:  Wang,Linlin;  Chen,Kuan;  Wang,Zilong;  Yi,Yang;  Zhang,Meng;  Hasan,Aobulikasimu;  Kuang,Yi;  Shaker,Sharpkate;  Yu,Rong;  Wang,Haotian;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
收藏  |  浏览/下载：49/0  |  提交时间：2022/04/02
ACYLATION  ACYLTRANSFERASE  CYCLOASTRAGENOL  BAHD  
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105314
作者:  Chen,Jing;  Yu,Yang;  Wu,Jing;  Bao,Mei-Fen;  Kongkiatpaiboon,Sumet;  Schinnerl,Johann;  Cai,Xiang-Hai
收藏  |  浏览/下载：47/0  |  提交时间：2022/04/02
Tabernaemontana divaricata 'Dwaft'  Monoterpenoid indole alkaloid  Aspidosperma-type trimmers  Aspidosperma-type dimers  Cytotoxicity  MONOTERPENOID INDOLE ALKALOIDS  BISINDOLE ALKALOIDS  DIVERSE SKELETONS  A-I  CONOPHYLLINE  
Discovery and heterologous production of sarubicins and quinazolinone C-glycosides with protecting activity for cardiomyocytes 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2021, 卷号: 8, 期号: 14, 页码: 3829-3837
作者:  Yu,Mingming;  Luo,Jianying;  Luo,Dan;  He,Qiang;  Yan,Yijun;  Ji,Xu;  Huang,Sheng-Xiong
浏览  |  Adobe PDF(1404Kb)  |  收藏  |  浏览/下载：84/33  |  提交时间：2022/04/02
STREPTOMYCES-VIOLACEORUBER TU22  BIOSYNTHESIS  GRANATICIN  ANTIBIOTICS  METABOLISM  MECHANISM  PATHWAY  ACID  
1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 30, 页码: 6650-6656
作者:  Huang,Jin-Quan;  Li,Dong-Mei;  Li,Jian-Xu;  Lin,Jia-Ling;  Tian,Xiu;  Wang,Ling-Jian;  Chen,Xiao-Ya;  Fang,Xin
浏览  |  Adobe PDF(2357Kb)  |  收藏  |  浏览/下载：59/17  |  提交时间：2022/04/02
ACTIVE-SITE RESIDUES  ARISTOLOCHENE SYNTHASE  ARTEMISIA-ANNUA  BIOLOGY  IDENTIFICATION  BIOSYNTHESIS  EXPRESSION  CLONING  GENES  
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' 期刊论文
BIOORGANIC CHEMISTRY, 2021
作者:  Chen,Jing;  Yu,Yang;  Wu,Jing;  Bao,Mei-Fen;  Kongkiatpaiboon,Sumet;  Schinnerl,Johann;  Cai,Xiang-Hai
浏览  |  Adobe PDF(1373Kb)  |  收藏  |  浏览/下载：102/31  |  提交时间：2023/09/08
Perrottetia taronensis BMBarthol. & K.Armstr., sp. nov. (Dipentodontaceae), a new species from northwestern Yunnan Province, China and northern Kachin State, Myanmar and a re-examination of the Asian and Australasian taxa of Perrottetia 期刊论文
PHYTOKEYS, 2021, 期号: 183, 页码: 67-76
作者:  Bartholomew,Bruce;  Armstrong,Kate E.;  Li,Rong;  Fritsch,Peter W.
浏览  |  Adobe PDF(3789Kb)  |  收藏  |  浏览/下载：96/33  |  提交时间：2022/04/02
Huerteales  IUCN Red List  Perrottetiaalpestris  Perrottetia arisanensis  
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
作者:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
Adobe PDF(8772Kb)  |  收藏  |  浏览/下载：69/15  |  提交时间：2022/04/02
PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
作者:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
Adobe PDF(523Kb)  |  收藏  |  浏览/下载：58/15  |  提交时间：2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Synthesis and anti-fibrotic effects of santamarin derivatives as cytotoxic agents against hepatic stellate cell line LX2 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 127994
作者:  Wang,Jin-Ping;  Li,Tian-Ze;  Huang,Xiao-Yan;  Geng,Chang-An;  Shen,Cheng;  Sun,Jin-Jin;  Xue,Dong;  Chen,Ji-Jun
Adobe PDF(567Kb)  |  收藏  |  浏览/下载：60/20  |  提交时间：2022/04/02
Santamarin derivatives  Anti-fibrotic effects  HSC-LX2  Extracellular matrix  NF-KAPPA-B  SESQUITERPENE LACTONES  LIVER FIBROSIS  STRUCTURE REQUIREMENT  BAY LEAF  ACTIVATION