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Hepatic Stellate Celland Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis 期刊论文
ACS NANO, 2023, 卷号: 17, 期号: 23, 页码: 23608-23625
作者:  Niu,Xia;  Meng,Yanan;  Cui,Jinjin;  Li,Rui;  Ding,Xiao;  Niu,Bingyu;  Chang,Ge;  Xu,Ning;  Li,Guiling;  Wang,Yucheng;  Wang,Lulu
浏览  |  Adobe PDF(5563Kb)  |  收藏  |  浏览/下载：173/27  |  提交时间：2024/07/10
liver fibrosis  dihydrotanshinone I  hepaticstellate cells  vitamin A  cyclodextrin  liver microbiome  STRATEGY  THERAPY  TARGET  NANOPARTICLES  PATHWAY  
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
浏览  |  Adobe PDF(5393Kb)  |  收藏  |  浏览/下载：243/43  |  提交时间：2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPARα agonists by in silico studies and biochemical evaluation 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 2256867
作者:  Li,Yue;  Lv,Mengjia;  Shen,Meiling;  Gu,Xi;  Zhang,Li;  Liu,Xingyong;  Chen,Jing;  Gong,Likun;  Zuo,Zhili
浏览  |  Adobe PDF(3338Kb)  |  收藏  |  浏览/下载：169/25  |  提交时间：2024/07/31
NAFLD  PPAR alpha agonist  virtual screening  biochemical evaluation  FATTY-ACID OXIDATION  GROMACS  
茵陈蒿和牛尾蒿的抗肝纤维化与抗肝癌活性成分研究 学位论文
: 中国科学院大学, 2022
作者:  高振
Adobe PDF(11670Kb)  |  收藏  |  浏览/下载：173/0  |  提交时间：2024/05/14
茵陈蒿，牛尾蒿，茵陈香豆酸，倍半萜二聚体，倍半萜，抗肝纤维化活性，抗肝癌活性，细胞周期，凋亡  Artemisia capillaris, Artemisia dubia, Coumaric acids, Sesquiterpenoids, Sesquiterpenoid dimers, Antihepatic fibrosis effects, Antihepatoma activity, Cell cycle, Apoptosis  
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice 期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 2411
作者:  Zhao, Zhuohui;  Deng, Zhen-Tao;  Huang, Suling;  Ning, Mengmeng;  Feng, Ying;  Shen, Yu;  Zhao, Qin-Shi;  Leng, Ying
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Alisol B  non-alcoholic steatohepatitis  RAR alpha  CD36  FATTY LIVER  HEPATIC STEATOSIS  RECEPTOR  ORIENTALE  LIPOPROTEINS  23-ACETATE  AGONIST  CD36  
Lipid Disorders in NAFLD and Chronic Kidney Disease 期刊论文
BIOMEDICINES, 2021, 卷号: 9, 期号: 10, 页码: 1405
作者:  Yang,Meng;  Geng,Chang-An;  Liu,Xinguang;  Guan,Min
收藏  |  浏览/下载：155/0  |  提交时间：2022/04/02
lipid  NAFLD  chronic kidney disease  NONALCOHOLIC FATTY LIVER  ENDOPLASMIC-RETICULUM STRESS  MESENCHYMAL STEM-CELLS  INSULIN-RESISTANCE  LIPOPROTEIN METABOLISM  OBETICHOLIC ACID  RENAL-FIBROSIS  RECEPTOR-ALPHA  MOUSE MODEL  ER STRESS  
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：305/86  |  提交时间：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Secoiridoids and triterpenoids from the traditional Tibetan medicine Gentiana veitchiorum and their immunosuppressive activity 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 192, 页码: 112961
作者:  Guo,Kai;  Zhou,Ting-Ting;  Ren,Xue;  Li,Dan;  Hu,Hong;  Liu,Yan-Chun;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(1682Kb)  |  收藏  |  浏览/下载：314/94  |  提交时间：2022/04/02
Gentiana veitchiorum  Gentianaceae  Secoiridoids  Triterpenoids  Immunosuppressive activity  CONSTITUENTS  HEMSL.  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
浏览  |  Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：258/55  |  提交时间：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' 期刊论文
BIOORGANIC CHEMISTRY, 2021
作者:  Chen,Jing;  Yu,Yang;  Wu,Jing;  Bao,Mei-Fen;  Kongkiatpaiboon,Sumet;  Schinnerl,Johann;  Cai,Xiang-Hai
浏览  |  Adobe PDF(1373Kb)  |  收藏  |  浏览/下载：377/89  |  提交时间：2023/09/08