Compounds from the Roots of Codonopsis pilosula and Their SIRT1 Regulatory Activity | |
Zheng, Tao1,2; Cheng, Li-Zhi1,4; Yan, Yong-Ming3; Xu, Fu-Rong2; Tang, Xiao-Long3; Li, Xiao-Zhen1,2; Qin, Fu-Ying1; Liu, Bao-Hua3; Cheng, Yong-Xian1,3,4 | |
2018 | |
发表期刊 | NATURAL PRODUCT COMMUNICATIONS
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ISSN | 1934-578X |
卷号 | 13期号:1页码:37-40 |
摘要 | Two new compounds, pilosuloside A (1) and pilosulain A (2), one new natural occurring compound (3), and twelve known compounds (4-15), were isolated from the roots of Codonopsis pilosula. Their structures were elucidated by a combination of spectroscopic methods. Regulation of SIRT1 activity by all the compounds was evaluated. The results showed that 4 could activate SIRT1 in a concentration-dependent manner. |
关键词 | Codonopsis Pilosula Pilosuloside a Pilosulain a Alkaloids Terpenoids |
语种 | 英语 |
WOS记录号 | WOS:000423651000011 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/60581 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Univ Tradit Chinese Med, Kunming 650504, Yunnan, Peoples R China 3.Shenzhen Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Shenzhen 518060, Peoples R China 4.Henan Univ Tradit Chinese Med, Zhengzhou 450008, Henan, Peoples R China |
推荐引用方式 GB/T 7714 | Zheng, Tao,Cheng, Li-Zhi,Yan, Yong-Ming,et al. Compounds from the Roots of Codonopsis pilosula and Their SIRT1 Regulatory Activity[J]. NATURAL PRODUCT COMMUNICATIONS,2018,13(1):37-40. |
APA | Zheng, Tao.,Cheng, Li-Zhi.,Yan, Yong-Ming.,Xu, Fu-Rong.,Tang, Xiao-Long.,...&Cheng, Yong-Xian.(2018).Compounds from the Roots of Codonopsis pilosula and Their SIRT1 Regulatory Activity.NATURAL PRODUCT COMMUNICATIONS,13(1),37-40. |
MLA | Zheng, Tao,et al."Compounds from the Roots of Codonopsis pilosula and Their SIRT1 Regulatory Activity".NATURAL PRODUCT COMMUNICATIONS 13.1(2018):37-40. |
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