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Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1889-1906
作者:  Li, Yaping;  Wu, Dong-mei;  Kong, Ling-mei;  Zhang, Shuqun;  Du, Haibo;  Sun, Wei;  Zhang, Li;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：120/0  |  提交时间：2020/03/26
bioassay  ensemble docking  scoring function  virtual screening  Wee1 inhibitors  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：150/34  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
作者:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Adobe PDF(2044Kb)  |  收藏  |  浏览/下载：247/28  |  提交时间：2019/03/18
Enantioselective N-Heterocyclic Carbene-Catalyzed Synthesis of Spirocyclic Oxindole-benzofuroazepinones 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 24, 页码: 15225-15235
作者:  Gao, Zhong-Hua;  Chen, Kun-Quan;  Zhang, Yan;  Kong, Ling-Mei;  Li, Yan;  Ye, Song
收藏  |  浏览/下载：222/0  |  提交时间：2019/03/18
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 14, 页码: 3911-3914
作者:  Wang, Li;  Yang, Jing;  Kong, Ling-Mei;  Deng, Jun;  Xiong, Zijun;  Huang, Jianping;  Luo, Jianping;  Yan, Yijun;  Hu, Yikao;  Li, Xiao-Nian;  Li, Yan;  Zhao, Yong;  Huang, Sheng-Xiong
Adobe PDF(1338Kb)  |  收藏  |  浏览/下载：261/74  |  提交时间：2017/10/23
Protein-kinase-c  Phorbol Esters  Biological Evaluation  Biosynthesis  (+)-phorbol  Analogs  Cancer  Seeds  
Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 5, 页码: 1108-1111
作者:  Yan, Bing-Chao;  Wang, Wei-Guang;  Hu, Dong-Bao;  Sun, Xiang;  Kong, Ling-Mei;  Li, Xiao-Nian;  Du, Xue;  Luo, Shi-Hong;  Liu, Yan;  Li, Yan;  Sun, Han-Dong;  Pu, Jian-Xin
Adobe PDF(881Kb)  |  收藏  |  浏览/下载：231/67  |  提交时间：2016/06/27
Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 9, 页码: 10203-10214
作者:  Kong, Ling-Mei;  Feng, Tao;  Wang, Yuan-Yuan;  Li, Xing-Yao;  Ye, Zhen-Nan;  An, Tao;  Qing, Chen;  Luo, Xiao-Dong;  Li, Yan
Adobe PDF(7290Kb)  |  收藏  |  浏览/下载：228/49  |  提交时间：2016/08/22
Bisleuconothine a  Inhibitor  Wnt Signaling  Colorectal Cancer Cells  
N-羟基邻苯二甲酰亚胺类化合物在制备抗肿瘤药物中的应用 专利
专利类型: 发明, 专利号: CN201510882376.4, 申请日期: 2015-12-04, 公开日期: 2016-03-30
发明人:  周宏宇;  李艳;  夏成峰;  孔令梅;  周安坤;  王敏
Adobe PDF(822Kb)  |  收藏  |  浏览/下载：371/20  |  提交时间：2016/12/19
ent-Kauranoids isolated from Isodon eriocalyx var. laxiflora and their structure activity relationship analyses 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 48, 页码: 9161-9171
作者:  Wang,Wei-Guang;  Yang,Jin;  Wu,Hai-Yan;  Kong,Ling-Mei;  Su,Jia;  Li,Xiao-Nian;  Du,Xue;  Zhan,Rui;  Zhou,Min;  Li,Yan;  Pu,Jian-Xin;  Sun,Han-Dong
Adobe PDF(1109Kb)  |  收藏  |  浏览/下载：223/54  |  提交时间：2016/01/19
Ent-kaurane  Diterpenoids  Isodon  
New cytotoxic and anti-inflammatory compounds isolated from Morus alba L. 期刊论文
NATURAL PRODUCT RESEARCH, 2015, 卷号: 29, 期号: 18, 页码: 1711-1718
作者:  Qin,Jing;  Fan,Min;  He,Juan;  Wu,Xing-De;  Peng,Li-Yan;  Su,Jia;  Cheng,Xiao;  Li,Yan;  Kong,Ling-Mei;  Li,Rong-Tao;  Zhao,Qin-Shi
Adobe PDF(626Kb)  |  收藏  |  浏览/下载：252/72  |  提交时间：2016/01/19
Morus Alba l  Soroceal b  Sanggenol q  Cytotoxic Activity  Anti-inflammatory Activity