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An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
Authors:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
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Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
Authors:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
Favorite  |  View/Download：106/0  |  Submit date：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Identification of Novel TRPC5 Inhibitors by Pharmacophore-Based and Structure-Based Approaches 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2020
Authors:  Li, Shuxiang;  Zhang, Shuqun;  Chen, Dingyuan;  Jiang, Xuan;  Liu, Bin;  Zhang, Hongbin;  Rachakunta, Munikishore;  Zuo, Zhili
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Computational simulation studies on the binding selectivity of Wee1 and Checkpoint kinase 1 by molecular dynamics simulation combined with free energy calculations 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020
Authors:  Li, Yaping;  Liu, Xingyong;  Zhang, Shuqun;  Wang, Liangliang;  Zhang, Li;  Zuo, Zhili
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Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
Authors:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
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delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1889-1906
Authors:  Li, Yaping;  Wu, Dong-mei;  Kong, Ling-mei;  Zhang, Shuqun;  Du, Haibo;  Sun, Wei;  Zhang, Li;  Li, Yan;  Zuo, Zhili
Favorite  |  View/Download：79/0  |  Submit date：2020/03/26
bioassay  ensemble docking  scoring function  virtual screening  Wee1 inhibitors  
苯并噻唑类及苯并吡咯类化合物在制备抗肿瘤药物中的应用 专利
申请日期: 2018-06-28, 公开日期: 2018-10-16
Inventors:  左之利;  李雅萍;  张树群;  刘兴勇;  李艳;  张利
Favorite  |  View/Download：85/0  |  Submit date：2019/08/14
青蒿素-苯胺基喹唑啉类衍生物及其制备方法和应用 专利
申请日期: 2018-05-16, 公开日期: 2018-09-04
Inventors:  左之利;  张树群;  刘辉;  李艳;  张云琴;  汪亮亮
Favorite  |  View/Download：81/0  |  Submit date：2019/08/14
Antitumor Research on Artemisinin and Its Bioactive Derivatives. 期刊论文
Natural products and bioprospecting, 2018, 卷号: 8, 期号: 4, 页码: 303-319
Authors:  Zhang, Yunqin;  Xu, Guowei;  Zhang, Shuqun;  Wang, Dong;  Saravana Prabha, P;  Zuo, Zhili
Favorite  |  View/Download：55/0  |  Submit date：2019/03/29
四氢吡啶并[4,5 ]噻吩并[2,3 ]嘧啶 4(3) 酮类化合物在制药中的应用 专利
申请日期: 2017-08-01, 公开日期: 2017-11-21
Inventors:  左之利;  李雅萍;  张树群;  杨静;  张利;  刘兴勇
Favorite  |  View/Download：82/0  |  Submit date：2018/05/10