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Biomimetic Intramolecular Diels-Alder Reaction to Construct the Tetrahydroindane Core of Elansolid A1/A2 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 7, 页码: 2820-2830
Authors:  Yu Qi;  Yang Shuai;  Tang Congyun;  Peng Lin;  Zuo Zhili;  Wang Liangliang
Adobe PDF(657Kb)  |  Favorite  |  View/Download：24/0  |  Submit date：2022/04/02
biomimetic synthesis  Diels-Alder reaction  tetrahydroindane  elansolid  ACID  OLEFIN  
The geometry of the compound leaf plays a significant role in the leaf movement of Medicago truncatula modulated by mtdwarf4a 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 230, 期号: 2, 页码: 475-484
Authors:  Zhao,Weiyue;  Bai,Quanzi;  Zhao,Baolin;  Wu,Qing;  Wang,Chaoqun;  Liu,Ye;  Yang,Tianquan;  Liu,Yu;  He,Hua;  Du,Shanshan;  Tadege,Million;  He,Liangliang;  Chen,Jianghua
Favorite  |  View/Download：11/0  |  Submit date：2022/04/02
brassinosteroid (BR) biosynthesis  compound leaf geometry  DWARF4  leaf movement  Medicago truncatula  pulvinus  POTASSIUM  RECEPTOR  GROWTH  GENE  BRASSINOSTEROIDS  RETROTRANSPOSON  IDENTIFICATION  PHYTOCHROME  MUTANT  
The F-box protein MIO1/SLB1 regulates organ size and leaf movement in Medicago truncatula 期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2021, 卷号: 72, 期号: 8, 页码: 2995-3011
Authors:  Zhou,Shaoli;  Yang,Tianquan;  Mao,Yawen;  Liu,Ye;  Guo,Shiqi;  Wang,Ruoruo;  Fangyue,Genwang;  He,Liangliang;  Zhao,Baolin;  Bai,Quanzi;  Li,Youhan;  Zhang,Xiaojia;  Wang,Dongfa;  Wang,Chaoqun;  Wu,Qing;  Yang,Yuanfan;  Liu,Yu;  Tadege,Million;  Chen,Jianghua
Favorite  |  View/Download：19/0  |  Submit date：2022/04/02
BIG SEEDS1 (BS1)  F-box protein  MINI ORGAN1 (MIO1)/SMALL LEAF AND BUSHY1 (SLB1)  SCF E3 ligase  proteasome-mediated degradation  organ size  pulvinus  CELL-PROLIFERATION  ARABIDOPSIS-THALIANA  TRANSCRIPTION FACTOR  SEED SIZE  GROWTH  GENE  IDENTIFICATION  KINASES  CYCLE  E2FB  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
Authors:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
Favorite  |  View/Download：93/0  |  Submit date：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Computational simulation studies on the binding selectivity of Wee1 and Checkpoint kinase 1 by molecular dynamics simulation combined with free energy calculations 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020
Authors:  Li, Yaping;  Liu, Xingyong;  Zhang, Shuqun;  Wang, Liangliang;  Zhang, Li;  Zuo, Zhili
Adobe PDF(2066Kb)  |  Favorite  |  View/Download：64/11  |  Submit date：2021/01/05
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
Authors:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
Adobe PDF(1542Kb)  |  Favorite  |  View/Download：95/23  |  Submit date：2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
2,3-二氢-4(1H)-喹唑啉酮类化合物及其药物组合物和其应用 专利
申请日期: 2019-01-08, 公开日期: 2019-03-29
Inventors:  左之利;  杨淬;  汪亮亮;  李朋华;  高俐
Favorite  |  View/Download：263/0  |  Submit date：2019/08/14
Recent Topics in Research and Development of Opioid Drugs 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 38, 期号: 10, 页码: 2625-2632
Authors:  Pan Chenling;  Meng Hao;  Wang Liangliang;  Shen Yuchai;  Zuo Zhili;  Wang Guanlin;  Chang Kwen-jen
Favorite  |  View/Download：193/0  |  Submit date：2018/12/18
opioid drug  opioid receptor  opioid side effects  drug research  
青蒿素-苯胺基喹唑啉类衍生物及其制备方法和应用 专利
申请日期: 2018-05-16, 公开日期: 2018-09-04
Inventors:  左之利;  张树群;  刘辉;  李艳;  张云琴;  汪亮亮
Favorite  |  View/Download：77/0  |  Submit date：2019/08/14
阿片类药物研发近期热点 期刊论文
有机化学, 2018, 页码: 10
Authors:  潘陈玲;  孟浩;  汪亮亮;  沈悦海;  左之利;  王冠林;  张宽仁
Favorite  |  View/Download：76/0  |  Submit date：2018/11/26
阿片药物  阿片受体  阿片样副作用  药物研究