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Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：10/3  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
先导化合物设计与开发 学位论文
: 中国科学院大学, 2022
作者:  Munikishore Rachakunta
Microsoft Word(14465Kb)  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/05/14
Buxus alkaloids  Buxus alkaloids  Cyclovirobuxine-D  Cyclovirobuxine-D  Synthesis, Calcium channel inhibitors  Synthesis, Calcium channel inhibitors  SAR studies  SAR studies  Anti-cardiovascular agents.  Anti-cardiovascular agents.  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
作者:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
浏览  |  Adobe PDF(523Kb)  |  收藏  |  浏览/下载：87/23  |  提交时间：2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Volatile Constituents of Endophytic Fungi Isolated from Aquilaria sinensis with Descriptions of Two New Species of Nemania 期刊论文
LIFE-BASEL, 2021, 卷号: 11, 期号: 4, 页码: 363
作者:  Tibpromma,Saowaluck;  Zhang,Lu;  Karunarathna,Samantha C.;  Du,Tian-Ye;  Phukhamsakda,Chayanard;  Rachakunta,Munikishore;  Suwannarach,Nakarin;  Xu,Jianchu;  Mortimer,Peter E.;  Wang,Yue-Hu
浏览  |  Adobe PDF(15322Kb)  |  收藏  |  浏览/下载：93/12  |  提交时间：2022/04/02
agarwood  chemical constituents  endophytic fungi  GC-MS analysis  PHYLOGENETIC-RELATIONSHIPS  AGARWOOD  
Identification of Novel TRPC5 Inhibitors by Pharmacophore-Based and Structure-Based Approaches 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2020
作者:  Li, Shuxiang;  Zhang, Shuqun;  Chen, Dingyuan;  Jiang, Xuan;  Liu, Bin;  Zhang, Hongbin;  Rachakunta, Munikishore;  Zuo, Zhili
浏览  |  Adobe PDF(4261Kb)  |  收藏  |  浏览/下载：154/40  |  提交时间：2021/01/05