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Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
Authors:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
Favorite  |  View/Download：11/0  |  Submit date：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
Authors:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Favorite  |  View/Download：113/0  |  Submit date：2019/03/18
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
Authors:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
Favorite  |  View/Download：295/0  |  Submit date：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
12th全国天然有机化学学术会议摘要集 会议录
Editors:  中国化学会
Adobe PDF(123481Kb)  |  Favorite  |  View/Download：52/6  |  Submit date：2018/10/24
Research Progress of Polycyclic Polyprenylated Acylphloroglucinols 期刊论文
CHEMICAL REVIEWS, 2018, 卷号: 118, 期号: 7, 页码: 3508-3558
Authors:  Yang, Xing-Wei;  Grossman, Robert B.;  Xu, Gang
View  |  Adobe PDF(27097Kb)  |  Favorite  |  View/Download：167/32  |  Submit date：2018/05/08
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
Authors:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
Favorite  |  View/Download：333/0  |  Submit date：2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1) 期刊论文
BIOMOLECULAR NMR ASSIGNMENTS, 2018, 卷号: 12, 期号: 1, 页码: 145-148
Authors:  Ma, Xiaofang;  Zhang, Yingying;  Liu, Bin;  Yang, Jiahui;  Hu, Kaifeng
View  |  Adobe PDF(823Kb)  |  Favorite  |  View/Download：42/8  |  Submit date：2018/05/08
Ror1  Kringle  Nmr  
Efficient synthesis of new phenanthridine Wnt/b-catenin signaling pathway agonists 期刊论文
European Journal of Medicinal Chemistry, 2018, 卷号: 157, 页码: 1491-1499
Authors:  Duozhi Chen;  Heng Zhang;  Chenxu Jing;  Xiaoli He;  Bijuan Yang;  Jieyun Cai;  Yunfu Zhou;  Xiaoming Song;  Lin Li;  Xiaojiang Hao
View  |  Adobe PDF(1966Kb)  |  Favorite  |  View/Download：73/31  |  Submit date：2019/03/27
ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus 期刊论文
OPEN BIOLOGY, 2017, 卷号: 7, 期号: 8, 页码: 170122
Authors:  Ma, Pengcheng;  Ren, Biyu;  Yang, Xiangcai;  Sun, Bin;  Liu, Xiaoliang;  Kong, Qinghua;  Li, Chaocui;  Mao, Bingyu
View  |  Adobe PDF(1985Kb)  |  Favorite  |  View/Download：56/9  |  Submit date：2017/10/23
Zc4h2  Smad  Smurf  Bone Morphogenesis Protein Signalling  Neural Development  
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 14, 页码: 3911-3914
Authors:  Wang, Li;  Yang, Jing;  Kong, Ling-Mei;  Deng, Jun;  Xiong, Zijun;  Huang, Jianping;  Luo, Jianping;  Yan, Yijun;  Hu, Yikao;  Li, Xiao-Nian;  Li, Yan;  Zhao, Yong;  Huang, Sheng-Xiong
View  |  Adobe PDF(1338Kb)  |  Favorite  |  View/Download：133/37  |  Submit date：2017/10/23
Protein-kinase-c  Phorbol Esters  Biological Evaluation  Biosynthesis  (+)-phorbol  Analogs  Cancer  Seeds