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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
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Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
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Abt-263  Sorafenib  Combination Therapy  Cancer  
Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines 期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
Authors:  Ming-Ju Hsieh;  Chiao-Wen Lin;  Shun-Fa Yang;  Mu-Kuan Chen;  Hui-Ling Chiou
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Glabridin  Migration  Invasion  Matrix Metalloproteinase-9  Hepatoma  
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
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Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
Artemongolins A-K, undescribed germacrane-guaiane sesquiterpenoid dimers from Artemisia mongolica and their antihepatoma activities 期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2023, 卷号: 46, 期号: 9-10, 页码: 782-794
Authors:  Shang,Chong;  Ma,Yun-Bao;  Wang,Yuan;  He,Xiao-Feng;  Li,Tian-Ze;  Chen,Ji-Jun
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Artemisia mongolica  Artemongolins A-K  Sesquiterpenoid dimers  Antihepatoma activity  HEPATOCELLULAR-CARCINOMA  LACTONE  ARGYI  
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
Authors:  Chen,Yuanzhi;  He,Zhicheng;  Yang,Shuting;  Chen,Cheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
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Runt-related transcription factor 1 (RUNX1)  High-grade serous ovarian carcinoma (HGSOC)  Apoptosis  EMT  Clinical therapeutic target  EPITHELIAL-MESENCHYMAL TRANSITIONS  HEPATOCELLULAR-CARCINOMA  TRANSCRIPTION FACTOR  TP53 MUTATIONS  UP-REGULATION  TUMOR-GROWTH  MIGRATION  PROLIFERATION  INVASION  FOXO1  
Cytotoxic and pro-apoptotic effects of botanical drugs derived from the indigenous cultivated medicinal plant Paris polyphylla var. yunnanensis 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1100825
Authors:  Yan,Xiu-Xiang;  Zhao,Yan-Qiang;  He,Yun;  Disayathanoowat,Terd;  Pandith,Hataichanok;  Inta,Angkhana;  Yang,Li-Xin
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Paris polyphylla var  yunnanensis  indigenous medicine knowledge  saponins  cytotoxic effects  pro-apoptotic effects  CELL-CYCLE ARREST  STEROIDAL SAPONINS  HEPATOCELLULAR-CARCINOMA  CHEMICAL-CONSTITUENTS  ASSAY  GLYCOSIDES  LEAVES  GROWTH  STEMS  SITES  
多花蒿中流份 B 和 E 的抗肝癌活性成分研究 学位论文
: 中国科学院大学, 2022
Authors:  张鑫
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多花蒿,多花蒿素 A~L,吉玛烷型倍半萜,抗肝癌细胞毒活性  Artemisia myriantha, artemyrianosins A~L, germacrane sesquiterpenoids, antihepatoma activity  
茵陈蒿和牛尾蒿的抗肝纤维化与抗肝癌活性成分研究 学位论文
: 中国科学院大学, 2022
Authors:  高振
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茵陈蒿,牛尾蒿,茵陈香豆酸,倍半萜二聚体,倍半萜,抗肝纤维化活性,抗肝癌活性,细胞周期,凋亡  Artemisia capillaris, Artemisia dubia, Coumaric acids, Sesquiterpenoids, Sesquiterpenoid dimers, Antihepatic fibrosis effects, Antihepatoma activity, Cell cycle, Apoptosis  
愈创木烷倍半萜 ludartin 衍生物合成与抗 肝癌活性研究 学位论文
: 中国科学院大学, 2022
Authors:  孙金金
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Ludartin 衍生物合成  Synthesis of ludartin derivatives, Antihepatoma activity, HepG2 cells, Huh7 cells  抗肝癌活性  HepG2 细胞  Huh7 细胞