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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:
Jingru Li
;
Yicheng Chen
;
Jiali Wan
;
Xin Liu
;
Chunrong Yu
;
Wenhua Li
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Submit date:2017/07/24
Abt-263
Sorafenib
Combination Therapy
Cancer
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins
期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
Authors:
Pauline Macheboeuf
;
Delphine S Fischer
;
Tom Brown Jr
;
Astrid Zervosen
;
Andre´Luxen
;
Bernard Joris
;
Andrea Dessen
;
Christopher J Schofield
Adobe PDF(425Kb)
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View/Download:171/1
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Submit date:2017/07/21
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+
期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
Authors:
M Song
;
D Chen
;
S P Yu
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Submit date:2017/07/24
Skf 96365
Trpc Channel
Glioblastoma
Calcium
na+/ca2+ Exchanger
Cell Cycle
Cell Death
Guaiane-type Sesquiterpenoid Dimers from Artemisia zhongdianensis and Antihepatoma Carcinoma Activity via the p38MAPK Pathway
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 19, 页码: 2453-2468
Authors:
Dong,Wei
;
Ma,Wen-Jing
;
Ma,Yun-Bao
;
Li,Feng-Jiao
;
Li,Tian-Ze
;
Wang,Yong-Cui
;
He,Xiao-Feng
;
Geng,Chang-An
;
Zhang,Xue-Mei
;
Chen,Ji-Jun
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Submit date:2024/07/10
Artemzhongdianolides B1-B17
Artemisia zhongdianensis
Guaiane-type sesquiterpenoid dimers
Antihepatoma activity
p38MAPK pathway
Cancer
NMR spectroscopy
X-ray diffraction
ARREST
CELLS
JNK
Artemeriopolides A-D, two types of sesquiterpenoid dimers with rare carbon skeletons from Artemisia eriopoda and their antihepatoma cytotoxicity
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 11, 页码: 2635-2641
Authors:
He,Xiao-Feng
;
Li,Qi-Hao
;
Li,Tian-Ze
;
Ma,Yun-Bao
;
Dong,Wei
;
Yang,Ke-Xin
;
Geng,Chang-An
;
Zhang,Hao-Wei
;
Wang,Yuan
;
Chen,Ji-Jun
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Submit date:2024/07/22
Development of actein derivatives as potent anti-triple negative breast cancer agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 89, 页码: 129307
Authors:
Zhang,Honglin
;
Chen,Yiyan
;
Huang,Songwen
;
Xiao,Wen-Wen
;
Qiu,Ming-Hua
;
Shao,Li-Dong
;
Chen,Chuan-Huizi
;
Li,Dashan
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Submit date:2024/07/22
Actein
Modification
Triple negative breast cancer
Structure-activity relationships
Mechanism
GROWTH-INHIBITORY ACTIVITY
BLACK COHOSH
EXTRACTS
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii
期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106512
Authors:
Tan,Qian
;
Hu,Kun
;
Li,Xiao-Nian
;
Yang,Xing-Zhi
;
Sun,Han-Dong
;
Puno,Pema-Tenzin
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View/Download:103/14
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Submit date:2024/07/22
Isodon wardii
ent-Kauranoids
Cytotoxicity
Apoptosis
Cell cycle
Cytotoxic and pro-apoptotic effects of botanical drugs derived from the indigenous cultivated medicinal plant Paris polyphylla var. yunnanensis
期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1100825
Authors:
Yan,Xiu-Xiang
;
Zhao,Yan-Qiang
;
He,Yun
;
Disayathanoowat,Terd
;
Pandith,Hataichanok
;
Inta,Angkhana
;
Yang,Li-Xin
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View/Download:108/10
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Submit date:2024/05/09
Paris polyphylla var
yunnanensis
indigenous medicine knowledge
saponins
cytotoxic effects
pro-apoptotic effects
CELL-CYCLE ARREST
STEROIDAL SAPONINS
HEPATOCELLULAR-CARCINOMA
CHEMICAL-CONSTITUENTS
ASSAY
GLYCOSIDES
LEAVES
GROWTH
STEMS
SITES
山地香茶菜的化学成分及其生物活性研究
学位论文
: 中国科学院大学, 2022
Authors:
邱彩玲
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Submit date:2024/05/14
山地香茶菜,二萜,细胞毒,促进溶酶体功能
Isodon oresbius, Diterpenoids, Cytotoxicity, Promotion of lysosomal function
新型天然铁死亡诱导剂的筛选及作用机制研究
学位论文
: 中国科学院大学, 2022
Authors:
赵越勤
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Submit date:2024/05/14
肿瘤,天然产物,铁死亡,溶酶体,p53
Cancer, Nature products, Ferroptosis, Lysosome, p53