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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  Favorite  |  View/Download:183/1  |  Submit date:2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal through inhibition of STAT3 pathway 期刊论文
出版物, 3111, 期号: 0, 页码: 1-50
Authors:  Jung Ok Ban;  Dae Hwan Kim;  Hee Pom Lee;  Chul Ju Hwang;  Jung-Hyun Shim;  Dae Joong Kim;  Tae Myoung Kim;  Heon Sang Jeong;  Seong Su Nah;  Hanyong Chen;  Zigang Dong;  Young Wan Ham;  Youngsoo Kim;  Sang-Bae Han;  Jin Tae Hong
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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:90/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
Authors:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  Favorite  |  View/Download:108/1  |  Submit date:2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112656
Authors:  Kaunda,Joseph Sakah;  Qin,Xu-Jie;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
Favorite  |  View/Download:18/0  |  Submit date:2022/04/02
Solanum violaceum  Solanaceae  Glycoalkaloids  Solanindiosides A-C  235,26R-hydroxylated spirostanoid saponin  Lignans  Cytotoxicity  Apoptosis  Antibacterial  Staphylococcus aureus  
Nine Unique Iridoids and Iridoid Glycosides From Patrinia scabiosaefolia 期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 657028
Authors:  Liu,Zhenhua;  Niu,Yun;  Zhou,Li;  Meng,Lijun;  Chen,Sitan;  Wang,Mengke;  Hu,Jiangmiao;  Kang,Wenyi
Favorite  |  View/Download:8/0  |  Submit date:2022/04/02
Patrinia scabiosaefolia  iridoid  iridoid glycoside  bis-iridoid glycoside  cytotoxic activity  
HRESIMS-guided isolation of aspidosperma-scandine type bisindole alkaloids from Melodinus cochinchinensis and their anti-inflammatory and cytotoxic activities 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112673
Authors:  Li,Fang-Ru;  Liu,Lu;  Liu,Ya-Ping;  Wang,Jin-Tang;  Yang,Mei-Lian;  Khan,Afsar;  Qin,Xu-Jie;  Wang,Yu-Dan;  Cheng,Gui-Guang
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Melodinus cochinchinensis (Lour.) Merr. (Apocynaceae)  melokhanines  Bisindole alkaloids  Anti-inflammatory  Cytotoxicity  MONOTERPENOID INDOLE ALKALOIDS  CHEMISTRY  FRUITS  
Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
Authors:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
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Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
Authors:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
Favorite  |  View/Download:9/0  |  Submit date:2022/04/02
Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Lepipyrrolins A-B, two new dimeric pyrrole 2-carbaldehyde alkaloids from the tubers of Lepidium meyenii 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104834
Authors:  Liu,Jun-Hong;  Zhang,Ran-Ran;  Peng,Xing-Rong;  Ding,Zhong-Tao;  Qiu,Ming-Hua
Favorite  |  View/Download:5/0  |  Submit date:2022/04/02
Lepidium meyenii  Pyrrole 2-carbaldehyde alkaloids  Dimers  Cytotoxicity  THIOHYDANTOIN DERIVATIVES  STRUCTURAL ELUCIDATION  MACA  MACAMIDES  WALP.  PLANT  CROP