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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
Authors:
Yang,Qihong
;
Qin,Tong
;
An,Tao
;
Wu,Hongna
;
Xu,Gang
;
Xiang,Jin
;
Lei,Kangfan
;
Zhang,Shaohua
;
Xia,Jie
;
Su,Guifeng
;
Wang,Dan
;
Xue,Minggao
;
Kong,Lingmei
;
Zhang,Wenxuan
;
Wu,Song
;
Li,Yan
View
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Submit date:2024/07/30
PORCN inhibitor
WHN-88
Palmitoylation
Wnt-driven cancers
SIGNALING PATHWAY
PORCUPINE
STEM
GENE
ACYLTRANSFERASE
MUTATIONS
POLARITY
PROTEIN
RNF43
MICE
Wnt/β-catenin信号通路调控NK细胞介导的肿瘤免疫和Brevinin-1RL1抗肿瘤研究
学位论文
, 2021
Authors:
居晓曼
Adobe PDF(6895Kb)
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View/Download:19/0
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Submit date:2024/03/20
基于Wnt信号通路调控的新型抗白癜风菲啶类活性化合物的研究
学位论文
, 2021
Authors:
杨碧娟
Adobe PDF(9995Kb)
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Submit date:2024/03/20
New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
Authors:
Su,Lihua
;
Zhang,Xintian
;
Ma,Yunbao
;
Geng,Changan
;
Huang,Xiaoyan
;
Hu,Jing
;
Li,Tianze
;
Tang,Shuang
;
Shen,Cheng
;
Gao,Zhen
;
Zhang,Xuemei
;
Chen,Ji-Jun
Adobe PDF(4074Kb)
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Submit date:2022/04/02
Guaianolide dimers
Artematrolides AeR
Artemisia atrovirens
Cytotoxicity
Cell cycle
Apoptosis
FARNESYL-PROTEIN TRANSFERASE
CELL-CYCLE ARREST
HEPATOCELLULAR-CARCINOMA
GUAIANOLIDES
LACTONES
INHIBITORS
ARTEMINOLIDE
APOPTOSIS
ARGYI
HELA
Novel Signature Genes and Pathways Identified for Human Left Ventricle Cardiomyopathies Rise from different Etiologies
期刊论文
Journal of Biomedical Research and Reviews, 2021
Authors:
Jiao Tian
;
Zheng Yuan Wu
;
Ying Ying He
;
Shubai Liu
Adobe PDF(1819Kb)
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Submit date:2023/09/08
Antimicrobial Peptide Brevivin-1RL1 from Frog Skin Secretion Induces Apoptosis and Necrosis of Tumor Cells
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 2059
Authors:
Ju,Xiaoman
;
Fan,Dongmei
;
Kong,Lingmei
;
Yang,Qihong
;
Zhu,Yiying
;
Zhang,Shaohua
;
Su,Guifeng
;
Li,Yan
Adobe PDF(3074Kb)
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Submit date:2022/04/02
antimicrobial peptide
Brevivin-1RL1
apoptosis
necrosis
caspase
anticancer
BULLFROG
PHOSPHATIDYLSERINE
MECHANISMS
ANTITUMOR
SURFACE
Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, accepted inhibits colorectal cancer stem cell growth
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 144, 页码: 112339
Authors:
He,YingYing
;
Liu,Shubai
;
Newburg,David S.
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Submit date:2022/04/02
Trametes versicolor
Cancer stem cell
Tyrosine kinase inhibitor
EGFR
Colorectal cancer
FACTOR RECEPTOR
POLYSACCHAROPEPTIDE
RESISTANCE
TARGET
EGFR
TOOL
PSP
DNA
CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell
期刊论文
ONCOGENESIS, 2021, 卷号: 10, 期号: 7, 页码: 49
Authors:
He,YingYing
;
He,Zhicheng
;
Lin,Jian
;
Chen,Cheng
;
Chen,Yuanzhi
;
Liu,Shubai
Adobe PDF(3008Kb)
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Submit date:2022/04/02
BINDING-PROTEIN CTBP
TRANSCRIPTIONAL COREPRESSOR
NEGATIVE MODULATION
PROMOTES APOPTOSIS
GENE-EXPRESSION
DAMAGE RESPONSE
PK
OVEREXPRESSION
PHOSPHOPROTEIN
TRANSFORMATION
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
Authors:
Gou,Leilei
;
Yue,Grace Gar-Lee
;
Puno,Pema Tenzin
;
Lau,Clara Bik-San
Adobe PDF(1847Kb)
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Submit date:2022/04/02
Breast cancer
Mast cell
Macrophage
Natural products
Herbs
Extracts
TUMOR-ASSOCIATED MACROPHAGES
NF-KAPPA-B
MEDIATED ALLERGIC REACTIONS
PRO-INFLAMMATORY CYTOKINES
ANTIINFLAMMATORY ACTIVITY
ATOPIC-DERMATITIS
UMBROSA ROOT
TNF-ALPHA
IN-VIVO
C-KIT
Fluoxetine ameliorates depressive symptoms by regulating lncRNA expression in the mouse hippocampus
期刊论文
ZOOLOGICAL RESEARCH, 2021, 卷号: 42, 期号: 1, 页码: 28-42
Authors:
Zhang,Chuan-Ling
;
Li,Yi-Jia
;
Lu,Shuang
;
Zhang,Ting
;
Xiao,Rui
;
Luo,Huai-Rong
Adobe PDF(11037Kb)
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Submit date:2022/04/02
Depression
Elderly
Fluoxetine
LncRNA
Chronic unpredictable mild stress
LONG NONCODING RNA
NEUROTROPHIC FACTOR
MAJOR DEPRESSION
MILD STRESS
DRUG-NAIVE
PROTEIN
INFLAMMATION
MECHANISMS
BIOMARKERS
DISCOVERY