Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2
Yan, Bing-Chao1,4; Wang, Wei-Guang1; Hu, Dong-Bao3; Sun, Xiang2; Kong, Ling-Mei1; Li, Xiao-Nian1; Du, Xue1; Luo, Shi-Hong1; Liu, Yan1; Li, Yan1; Sun, Han-Dong1; Pu, Jian-Xin1
2016-03-04
Source PublicationORGANIC LETTERS
Volume18Issue:5Pages:1108-1111
AbstractPhomopchalasins A (1) and B (2), two novel cytochalasans with unprecedented carbon skeletons, and phomopchalasin C (3), containing a rare hydroperoxyl motif; were obtained from the endophytic fungus Phomopsis sp. shj2, which was first isolated from the Isodon eriocalyx var. laxiflora. Their structures were elucidated by extensive spectroscopic analyses, electronic circular dichroism (ECD) calculation, and X-ray crystallographic analysis. Notably, 1 possessed an unprecedented 5/6/5/8-fused tetracyclic ring system, and 2 featured a novel 5/6/6/7/5-fused pentacyclic skeleton. The cytotoxic, anti-inflammatory, and antimigratory activities of 1-3 were evaluated in vitro.
DOI10.1021/acs.orglett.6b00214
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Organic
WOS IDWOS:000371754000056
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/26012
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China
3.Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Yunnan, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Yan, Bing-Chao,Wang, Wei-Guang,Hu, Dong-Bao,et al. Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2[J]. ORGANIC LETTERS,2016,18(5):1108-1111.
APA Yan, Bing-Chao.,Wang, Wei-Guang.,Hu, Dong-Bao.,Sun, Xiang.,Kong, Ling-Mei.,...&Pu, Jian-Xin.(2016).Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2.ORGANIC LETTERS,18(5),1108-1111.
MLA Yan, Bing-Chao,et al."Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2".ORGANIC LETTERS 18.5(2016):1108-1111.
Files in This Item: Download All
File Name/Size DocType Version Access License
yan20162.pdf(881KB) 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yan, Bing-Chao]'s Articles
[Wang, Wei-Guang]'s Articles
[Hu, Dong-Bao]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yan, Bing-Chao]'s Articles
[Wang, Wei-Guang]'s Articles
[Hu, Dong-Bao]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yan, Bing-Chao]'s Articles
[Wang, Wei-Guang]'s Articles
[Hu, Dong-Bao]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: yan20162.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.