| Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2 | |
Yan, Bing-Chao1,4; Wang, Wei-Guang1; Hu, Dong-Bao3; Sun, Xiang2; Kong, Ling-Mei1; Li, Xiao-Nian1; Du, Xue1; Luo, Shi-Hong1; Liu, Yan1; Li, Yan1 ; Sun, Han-Dong1; Pu, Jian-Xin1
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| 2016-03-04 | |
| 发表期刊 | ORGANIC LETTERS
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| 卷号 | 18期号:5页码:1108-1111 |
| 摘要 | Phomopchalasins A (1) and B (2), two novel cytochalasans with unprecedented carbon skeletons, and phomopchalasin C (3), containing a rare hydroperoxyl motif; were obtained from the endophytic fungus Phomopsis sp. shj2, which was first isolated from the Isodon eriocalyx var. laxiflora. Their structures were elucidated by extensive spectroscopic analyses, electronic circular dichroism (ECD) calculation, and X-ray crystallographic analysis. Notably, 1 possessed an unprecedented 5/6/5/8-fused tetracyclic ring system, and 2 featured a novel 5/6/6/7/5-fused pentacyclic skeleton. The cytotoxic, anti-inflammatory, and antimigratory activities of 1-3 were evaluated in vitro. |
| DOI | 10.1021/acs.orglett.6b00214 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000371754000056 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/26012 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China 3.Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Yunnan, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yan, Bing-Chao,Wang, Wei-Guang,Hu, Dong-Bao,et al. Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2[J]. ORGANIC LETTERS,2016,18(5):1108-1111. |
| APA | Yan, Bing-Chao.,Wang, Wei-Guang.,Hu, Dong-Bao.,Sun, Xiang.,Kong, Ling-Mei.,...&Pu, Jian-Xin.(2016).Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2.ORGANIC LETTERS,18(5),1108-1111. |
| MLA | Yan, Bing-Chao,et al."Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2".ORGANIC LETTERS 18.5(2016):1108-1111. |
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