New cytotoxic and anti-inflammatory compounds isolated from Morus alba L.

doi:10.1080/14786419.2014.999333

	New cytotoxic and anti-inflammatory compounds isolated from Morus alba L.
	Qin,Jing; Fan,Min; He,Juan; Wu,Xing-De; Peng,Li-Yan; Su,Jia; Cheng,Xiao; Li,Yan; Kong,Ling-Mei; Li,Rong-Tao; Zhao,Qin-Shi
	2015-09-17
发表期刊	NATURAL PRODUCT RESEARCH
卷号	29 期号:18 页码:1711-1718
摘要	Six Diels-Alder adducts (1-6) and nine prenylated flavanones (7-15) were isolated from the root bark of Morus alba L. Among them, soroceal B (1) and sanggenol Q (7) were new compounds. Their structures were elucidated on the basis of extensive spectroscopic methods, including 1D and 2D NMR techniques. Compounds 1-3, 9, 10, 12, 13 and 15 exhibited cytotoxic activity against five human tumour lines and compound 2 inhibited significantly selective cytotoxic activities towards HL-60 and AGS cells with IC50 of 3.4 and 3.6M. Compounds 3, 5, 9 and 12 exhibited moderate inhibitory activity against nitric oxide production in LPS-activated RAW264.7.
关键词	Morus Alba l Soroceal b Sanggenol q Cytotoxic Activity Anti-inflammatory Activity
DOI	10.1080/14786419.2014.999333
收录类别	SCI
语种	英语
WOS记录号	WOS:000359849800004
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25102
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Qin,Jing,Fan,Min,He,Juan,et al. New cytotoxic and anti-inflammatory compounds isolated from Morus alba L.[J]. NATURAL PRODUCT RESEARCH,2015,29(18):1711-1718.
APA	Qin,Jing.,Fan,Min.,He,Juan.,Wu,Xing-De.,Peng,Li-Yan.,...&Zhao,Qin-Shi.(2015).New cytotoxic and anti-inflammatory compounds isolated from Morus alba L..NATURAL PRODUCT RESEARCH,29(18),1711-1718.
MLA	Qin,Jing,et al."New cytotoxic and anti-inflammatory compounds isolated from Morus alba L.".NATURAL PRODUCT RESEARCH 29.18(2015):1711-1718.

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