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Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载：3/0  |  提交时间：2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Development of a LC-HRMS based approach to boost structural annotation of isomeric citrus flavanones 期刊论文
PHYTOCHEMICAL ANALYSIS, 2021, 卷号: 32, 期号: 5, 页码: 749-756
作者:  He,Ying-Jie;  Zhou,Ying;  Qin,Yan;  Zhou,Zhong-Shun;  Zhu,Meng;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Xie,Tian-Zhen;  Zhao,Li-Xing;  Luo,Xiao-Dong
收藏  |  浏览/下载：69/0  |  提交时间：2022/04/02
citrus flavanones  collision energy  fragmentation pattern  high‐  resolution mass spectrometry  ion ratio  RESOLUTION MASS-SPECTROMETRY  HESPERETIN ENANTIOMERS  QUANTIFICATION  NARINGENIN  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2120Kb)  |  收藏  |  浏览/下载：142/42  |  提交时间：2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
作者:  Zhu,Pei-Feng;  Cheng,Gui-Guang;  Zhao,Lan-Qin;  Khan,Afsar;  Yang,Xing-Wei;  Zhang,Bu-Yun;  Li,Meng-Cheng;  Liu,Ya-Ping;  Luo,Xiao-Dong
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Rhynchanthus beesianus  diarylheptanoid  antioxidant activity  intracellular reactive oxygen species  cell apoptosis  GINGER ZINGIBER-OFFICINALE  PC12 CELLS  RHIZOMES  NEUROPROTECTION  ACTIVATION  ENZYMES  L.  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
浏览  |  Adobe PDF(5546Kb)  |  收藏  |  浏览/下载：111/44  |  提交时间：2022/04/02
Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：146/81  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Alkaloids of Toddalia asiatica (Rutaceae) 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2021, 卷号: 95, 页码: 104244
作者:  Chen,Shan-Shan;  Xie,Tian-Zhen;  He,Ying-Jie;  Liu,Yang-Yang;  Li,Lei;  Zhao,Li-Xing;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2707Kb)  |  收藏  |  浏览/下载：78/33  |  提交时间：2022/04/02
Toddalia asiatica  Rutaceae  Benzophenanthridine alkaloids  Furoquinoline alkaloids  Chemotaxonomy  Network analysis  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
作者:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1568Kb)  |  收藏  |  浏览/下载：65/16  |  提交时间：2022/04/02
SKELETONS  
C-19 Benzylisoquinoline Alkaloid with Unprecedented Architecture from Hypecoum erectum 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 23, 页码: 16764-16769
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Hu,Kun;  He,Ying-Jie;  Yang,Xing-Wei;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1336Kb)  |  收藏  |  浏览/下载：88/40  |  提交时间：2022/04/02
OPIUM POPPY  BIOSYNTHESIS  APORPHINE  TETRANDRINE  PAPAVERINE  DISCOVERY  
Bioassay-guided isolation of anti-inflammatory diterpenoids with highly oxygenated substituents from kidney tea (Clerodendranthus spicatus) 期刊论文
JOURNAL OF FOOD BIOCHEMISTRY, 2020
作者:  Chen, Wei-Di;  Zhao, Yun-Li;  Dai, Zhi;  Zhou, Zhong-Shun;  Zhu, Pei-Feng;  Liu, Ya-Ping;  Zhao, Li-Xing;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1146Kb)  |  收藏  |  浏览/下载：107/39  |  提交时间：2021/01/05