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Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
Authors:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
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Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
Authors:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
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Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Alkaloids of Toddalia asiatica (Rutaceae) 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2021, 卷号: 95, 页码: 104244
Authors:  Chen,Shan-Shan;  Xie,Tian-Zhen;  He,Ying-Jie;  Liu,Yang-Yang;  Li,Lei;  Zhao,Li-Xing;  Luo,Xiao-Dong
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Toddalia asiatica  Rutaceae  Benzophenanthridine alkaloids  Furoquinoline alkaloids  Chemotaxonomy  Network analysis  
Polar auxin transport May Be responsive to specific features of flavonoid structure 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 185, 页码: 112702
Authors:  Zhang,Xudong;  Huang,Xing;  Li,Yan;  Tao,Faqing;  Zhao,Qinshi;  Li,Weiqi
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Arabidopsis thaliana  Brassicaceae  Polar auxin transport  Flovonoids  Scutellarin  Scutellarein  Naringenin  Root growth  WUS-RELATED HOMEOBOX 5  
Polar auxin transport May Be responsive to specific features of flavonoid structure (vol 185, 112702, 2021) 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 188, 页码: 112801
Authors:  Zhang,Xudong;  Huang,Xing;  Li,Yan;  Tao,Faqing;  Zhao,Qinshi;  Li,Weiqi
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Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
Authors:  Zhu,Pei-Feng;  Cheng,Gui-Guang;  Zhao,Lan-Qin;  Khan,Afsar;  Yang,Xing-Wei;  Zhang,Bu-Yun;  Li,Meng-Cheng;  Liu,Ya-Ping;  Luo,Xiao-Dong
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Rhynchanthus beesianus  diarylheptanoid  antioxidant activity  intracellular reactive oxygen species  cell apoptosis  GINGER ZINGIBER-OFFICINALE  PC12 CELLS  RHIZOMES  NEUROPROTECTION  ACTIVATION  ENZYMES  L.  
Monoterpene Indole Alkaloids with Ca(v)3.1 T-Type Calcium Channel Inhibitory Activity from Catharanthus roseus 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 21, 页码: 6516
Authors:  Deng,Zhen-Tao;  Li,Wen-Yan;  Wang,Lei;  Zhou,Zhi-Ping;  Wu,Xing-De;  Ding,Zhong-Tao;  Zhao,Qin-Shi
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Catharanthus roseus  monoterpene indole alkaloid  catharanosine A  Ca(v)3  1 low voltage-gated calcium channel (LVGCC)  VINCA ALKALOIDS  CELL-PROLIFERATION  N-OXIDE  SARPAGINE  BIOSYNTHESIS  VINORELBINE  VINBLASTINE  MECHANISM  ROOTS  BASES  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
Authors:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
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Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN