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Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris
Hu,Bin-Yuan; Zhao,Yun-Li; Xiong,Deng-Sen; He,Ying-Jie; Zhou,Zhong-Shun; Zhu,Pei-Feng; Wang,Zhao-Jie; Wang,Yong-Liang; Zhao,Li-Xing; Luo,Xiao-Dong
2021
Source PublicationORGANIC LETTERS
ISSN1523-7060
Volume23Issue:11Pages:4158-4162
AbstractTwo rearranged triterpenoids, representing new subtypes of pentacyclic triterpenoids, with unique 6/6/6/7/5 and 6/6/5/6/6/6 ring systems were isolated from Alstonia scholaris. Their structures were established by spectroscopic analysis, single-crystal X-ray diffraction, and electronic circular dichroism calculations. Both compounds exhibited potent antihyperuricemic bioactivity in vitro and in vivo.
KeywordSKELETONS
DOI10.1021/acs.orglett.1c01102
WOS IDWOS:000661126700015
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Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/73025
Collection中国科学院昆明植物研究所
Affiliation1.[Hu, Bin-Yuan
2.Zhao, Yun-Li
3.Xiong, Deng-Sen
4.He, Ying-Jie
5.Zhou, Zhong-Shun
6.Wang, Zhao-Jie
7.Wang, Yong-Liang
8.Zhao, Li-Xing
9.Yunnan Univ, Yunnan Prov Ctr Res & Dev Nat Prod, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource,Minist Educ, Kunming 650091, Yunnan, Peoples R China
10.[Zhao, Yun-Li
11.Zhu, Pei-Feng
12.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Hu,Bin-Yuan,Zhao,Yun-Li,Xiong,Deng-Sen,et al. Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris[J]. ORGANIC LETTERS,2021,23(11):4158-4162.
APA Hu,Bin-Yuan.,Zhao,Yun-Li.,Xiong,Deng-Sen.,He,Ying-Jie.,Zhou,Zhong-Shun.,...&Luo,Xiao-Dong.(2021).Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris.ORGANIC LETTERS,23(11),4158-4162.
MLA Hu,Bin-Yuan,et al."Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris".ORGANIC LETTERS 23.11(2021):4158-4162.
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