Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris

doi:10.1021/acs.orglett.1c01102

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	Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris
	Hu,Bin-Yuan ; Zhao,Yun-Li ; Xiong,Deng-Sen ; He,Ying-Jie ; Zhou,Zhong-Shun ; Zhu,Pei-Feng ; Wang,Zhao-Jie ; Wang,Yong-Liang ; Zhao,Li-Xing ; Luo,Xiao-Dong
	2021
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	23 期号:11 页码:4158-4162
摘要	Two rearranged triterpenoids, representing new subtypes of pentacyclic triterpenoids, with unique 6/6/6/7/5 and 6/6/5/6/6/6 ring systems were isolated from Alstonia scholaris. Their structures were established by spectroscopic analysis, single-crystal X-ray diffraction, and electronic circular dichroism calculations. Both compounds exhibited potent antihyperuricemic bioactivity in vitro and in vivo.
关键词	SKELETONS
DOI	10.1021/acs.orglett.1c01102
WOS记录号	WOS:000661126700015
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73025
专题	中国科学院昆明植物研究所
作者单位	1.[Hu, Bin-Yuan 2.Zhao, Yun-Li 3.Xiong, Deng-Sen 4.He, Ying-Jie 5.Zhou, Zhong-Shun 6.Wang, Zhao-Jie 7.Wang, Yong-Liang 8.Zhao, Li-Xing 9.Yunnan Univ, Yunnan Prov Ctr Res & Dev Nat Prod, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource,Minist Educ, Kunming 650091, Yunnan, Peoples R China 10.[Zhao, Yun-Li 11.Zhu, Pei-Feng 12.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Hu,Bin-Yuan,Zhao,Yun-Li,Xiong,Deng-Sen,et al. Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris[J]. ORGANIC LETTERS,2021,23(11):4158-4162.
APA	Hu,Bin-Yuan.,Zhao,Yun-Li.,Xiong,Deng-Sen.,He,Ying-Jie.,Zhou,Zhong-Shun.,...&Luo,Xiao-Dong.(2021).Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris.ORGANIC LETTERS,23(11),4158-4162.
MLA	Hu,Bin-Yuan,et al."Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris".ORGANIC LETTERS 23.11(2021):4158-4162.

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