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Isorhynchophylline ameliorates stress-induced emotional disorder and cognitive impairment with modulation of NMDA receptors 期刊论文
FRONTIERS IN NEUROSCIENCE, 2022, 卷号: 16, 页码: 1071068
作者:  Wang, Chen;  Zhu, Ming-Hao;  Sun, Na;  Shen, Wei;  Jiang, Ning;  Zhao, Qin-Shi;  Zhang, Yong-Xiang;  Huang, Yan;  Zhou, Wen-Xia
浏览  |  Adobe PDF(4973Kb)  |  收藏  |  浏览/下载：50/4  |  提交时间：2024/08/21
isorhynchophylline (PubChem CID  3037048)  corticosterone  long-term potentiation  chronic unpredictable mild stress  D-serine  NMDA receptors  CHRONIC MILD STRESS  DEPRESSION-LIKE BEHAVIORS  SYNAPTIC PLASTICITY  HIPPOCAMPAL PLASTICITY  DENTATE GYRUS  CORTICOSTERONE  MEMORY  BRAIN  RHYNCHOPHYLLINE  IMPROVES  
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
作者:  Liu,Shuang;  Zhang,Taocui;  Sun,Huifang;  Lin,Lisha;  Gao,Na;  Wang,Weili;  Li,Sujuan;  Zhao,Jinhua
浏览  |  Adobe PDF(1230Kb)  |  收藏  |  浏览/下载：258/61  |  提交时间：2022/04/02
pharmacokinetics  pharmacodynamics  anticoagulant  fucosylated glycosaminoglycan  dHG-5  method validation  
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
作者:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
浏览  |  Adobe PDF(8336Kb)  |  收藏  |  浏览/下载：211/23  |  提交时间：2022/04/02
Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
作者:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
浏览  |  Adobe PDF(4401Kb)  |  收藏  |  浏览/下载：148/33  |  提交时间：2022/04/02
FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 256, 页码: 117513
作者:  Li,Xiaomei;  Li,Shanni;  Liu,Jie;  Lin,Lisha;  Sun,Huifang;  Yang,Wenjiao;  Cai,Ying;  Gao,Na;  Zhou,Lutan;  Qin,Hongbo;  Yin,Ronghua;  Zhao,Jinhua
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fucan sulfate  peroxide depolymerization  oligosaccharides  anti-thrombin activity  FUCOSYLATED CHONDROITIN SULFATE  FREE-RADICAL DEPOLYMERIZATION  PHYSICOCHEMICAL CHARACTERISTICS  REPEATING UNIT  BODY-WALL  SEA  FUCOIDAN  GLYCOSAMINOGLYCAN  POLYSACCHARIDES  HEPARIN  
Effects of Native Fucosylated Glycosaminoglycan, Its Depolymerized Derivatives on Intrinsic Factor Xase, Coagulation, Thrombosis, and Hemorrhagic Risk 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2020
作者:  Zhou, Lutan;  Gao, Na;  Sun, Huifang;  Xiao, Chuang;  Yang, Lian;  Lin, Lisha;  Yin, Ronghua;  Li, Zi;  Zhang, Hongbin;  Ji, Xu;  Zhao, Jinhua
浏览  |  Adobe PDF(1210Kb)  |  收藏  |  浏览/下载：336/70  |  提交时间：2021/01/05
From multi-target anticoagulants to DOACs, and intrinsic coagulation factor inhibitors 期刊论文
BLOOD REVIEWS, 2020
作者:  Lin, Lisha;  Zhao, Longyan;  Gao, Na;  Yin, Ronghua;  Li, Sujuan;  Sun, Huifang;  Zhou, Lutan;  Zhao, Guiling;  Purcell, Steven W.;  Zhao, Jinhua
浏览  |  Adobe PDF(943Kb)  |  收藏  |  浏览/下载：165/35  |  提交时间：2021/01/05
Genome-wide analysis of Cushion willow provides insights into alpine plant divergence in a biodiversity hotspot 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 12
作者:  Chen, Jia-hui;  Huang, Yuan;  Brachi, Benjamin;  Yun, Quan-zheng;  Zhang, Wei;  Lu, Wei;  Li, Hong-na;  Li, Wen-qing;  Sun, Xu-dong;  Wang, Guang-yan;  He, Jun;  Zhou, Zhuo;  Chen, Kai-yun;  Ji, Yun-heng;  Shi, Ming-ming;  Sun, Wen-guang;  Yang, Yong-ping;  Zhang, Ren-gang;  Abbott, Richard J.;  Sun, Hang
浏览  |  Adobe PDF(3471Kb)  |  收藏  |  浏览/下载：330/65  |  提交时间：2020/03/02
An ERF2-like transcription factor regulates production of the defense sesquiterpene capsidiol upon Alternaria alternata infection 期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2019, 卷号: 70, 期号: 20, 页码: 5895-5908
作者:  Song, Na;  Ma, Lan;  Wang, Weiguang;  Sun, Huanhuan;  Wang, Lei;  Baldwin, Ian T.;  Wu, Jinsong
浏览  |  Adobe PDF(3444Kb)  |  收藏  |  浏览/下载：249/37  |  提交时间：2020/03/18
5-epi-Aristolochene hydroxylase (EAH)  5-epi-aristolochene synthase (EAS)  ethylene responsive factor  Nicotiana attenuata  phytoalexin  sesquiterpene  virus induced gene silencing (VIGS)  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：303/82  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research