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Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
Authors:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
Favorite  |  View/Download:53/0  |  Submit date:2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Structure and heparanase inhibitory activity of a new glycosaminoglycan from the slug Limacus flavus 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 220, 页码: 176-184
Authors:  He, Zhicheng;  Zhou, Lutan;  Lin, Lisha;  Yin, Ronghua;  Zhao, Jinhua
Favorite  |  View/Download:38/0  |  Submit date:2019/07/29
Slug  Glycosaminoglycan  Chemical structure  Depolymerization  Heparanase inhibition  
Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 5, 页码: 705-715
Authors:  Xiao, Chuang;  Zhao, Longyan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
Favorite  |  View/Download:27/0  |  Submit date:2019/06/24
nonasaccharide from fucosylated glycosaminoglycan  intrinsic factor Xase complex  factor IXa  anticoagulant  
Orthogonal One-Pot Synthesis of Oligosaccharides Based on Glycosyl ortho-Alkynylbenzoates 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 7, 页码: 2335-2339
Authors:  Zhang, Yunqin;  Xiang, Guisheng;  He, Shaojun;  Hu, Yikao;  Liu, Yanjun;  Xu, Lili;  Xiao, Guozhi
Favorite  |  View/Download:49/0  |  Submit date:2019/05/24
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
Authors:  Guan, Ruowei;  Peng, Yuan;  Zhou, Lutan;  Zheng, Wenqi;  Liu, Xixi;  Wang, Pin;  Yuan, Qingxia;  Gao, Na;  Zhao, Longyan;  Zhao, Jinhua
Favorite  |  View/Download:31/0  |  Submit date:2019/06/24
Apostichopus japonicus  fucosylated glycosaminoglycan  oligosaccharide  unambiguous structure  anti-Fxase  
Microbe-focused glycan array screening platform 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 6, 页码: 1958-1967
Authors:  Geissner, Andreas;  Reinhardt, Anika;  Rademacher, Christoph;  Johannssen, Timo;  Monteiro, Joao;  Lepenies, Bernd;  Thepaut, Michel;  Fieschi, Franck;  Mrazkova, Jana;  Wimmerova, Michaela;  Schuhmacher, Frank;  Goetze, Sebastian;  Gruenstein, Dan;  Guo, Xiaoqiang;  Hahm, Heung Sik;  Kandasamy, Jeyakumar;  Leonori, Daniele;  Martin, Christopher E.;  Parameswarappa, Sharavathi G.;  Pasari, Sandip;  Schlegel, Mark K.;  Tanaka, Hidenori;  Xiao, Guozhi;  Yang, You;  Pereira, Claney L.;  Anish, Chakkumkal;  Seeberger, Peter H.
Favorite  |  View/Download:46/0  |  Submit date:2019/03/18
glycan arrays  microbial antigens  immune receptors  antiglycan antibodies  bacterial lectins  
Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
Authors:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
View  |  Adobe PDF(1568Kb)  |  Favorite  |  View/Download:99/14  |  Submit date:2018/10/22
Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
Authors:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(1313Kb)  |  Favorite  |  View/Download:85/6  |  Submit date:2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
Synthesis and anticoagulation studies of "short-armed" fucosylated chondroitin sulfate glycoclusters 期刊论文
CARBOHYDRATE RESEARCH, 2018, 卷号: 467, 页码: 45-51
Authors:  Liu, Huiying;  Zhang, Xiao;  Wu, Mingyi;  Li, Zhongjun
View  |  Adobe PDF(617Kb)  |  Favorite  |  View/Download:29/2  |  Submit date:2018/09/27
Fucosylated Chondroitin Sulfate  Glycocluster  Glycosaminoglycan  Anticoagulant  Carbohydrate  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
Authors:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(3117Kb)  |  Favorite  |  View/Download:102/14  |  Submit date:2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase