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Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 5, 页码: 705-715
Authors:  Xiao, Chuang;  Zhao, Longyan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
Favorite  |  View/Download:9/0  |  Submit date:2019/06/24
nonasaccharide from fucosylated glycosaminoglycan  intrinsic factor Xase complex  factor IXa  anticoagulant  
Orthogonal One-Pot Synthesis of Oligosaccharides Based on Glycosyl ortho-Alkynylbenzoates 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 7, 页码: 2335-2339
Authors:  Zhang, Yunqin;  Xiang, Guisheng;  He, Shaojun;  Hu, Yikao;  Liu, Yanjun;  Xu, Lili;  Xiao, Guozhi
Favorite  |  View/Download:41/0  |  Submit date:2019/05/24
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
Authors:  Guan, Ruowei;  Peng, Yuan;  Zhou, Lutan;  Zheng, Wenqi;  Liu, Xixi;  Wang, Pin;  Yuan, Qingxia;  Gao, Na;  Zhao, Longyan;  Zhao, Jinhua
Favorite  |  View/Download:7/0  |  Submit date:2019/06/24
Apostichopus japonicus  fucosylated glycosaminoglycan  oligosaccharide  unambiguous structure  anti-Fxase  
Microbe-focused glycan array screening platform 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 6, 页码: 1958-1967
Authors:  Geissner, Andreas;  Reinhardt, Anika;  Rademacher, Christoph;  Johannssen, Timo;  Monteiro, Joao;  Lepenies, Bernd;  Thepaut, Michel;  Fieschi, Franck;  Mrazkova, Jana;  Wimmerova, Michaela;  Schuhmacher, Frank;  Goetze, Sebastian;  Gruenstein, Dan;  Guo, Xiaoqiang;  Hahm, Heung Sik;  Kandasamy, Jeyakumar;  Leonori, Daniele;  Martin, Christopher E.;  Parameswarappa, Sharavathi G.;  Pasari, Sandip;  Schlegel, Mark K.;  Tanaka, Hidenori;  Xiao, Guozhi;  Yang, You;  Pereira, Claney L.;  Anish, Chakkumkal;  Seeberger, Peter H.
Favorite  |  View/Download:32/0  |  Submit date:2019/03/18
glycan arrays  microbial antigens  immune receptors  antiglycan antibodies  bacterial lectins  
Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
Authors:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
View  |  Adobe PDF(1568Kb)  |  Favorite  |  View/Download:65/7  |  Submit date:2018/10/22
Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
Authors:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(1313Kb)  |  Favorite  |  View/Download:54/3  |  Submit date:2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
Synthesis and anticoagulation studies of "short-armed" fucosylated chondroitin sulfate glycoclusters 期刊论文
CARBOHYDRATE RESEARCH, 2018, 卷号: 467, 页码: 45-51
Authors:  Liu, Huiying;  Zhang, Xiao;  Wu, Mingyi;  Li, Zhongjun
View  |  Adobe PDF(617Kb)  |  Favorite  |  View/Download:15/0  |  Submit date:2018/09/27
Fucosylated Chondroitin Sulfate  Glycocluster  Glycosaminoglycan  Anticoagulant  Carbohydrate  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
Authors:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(3117Kb)  |  Favorite  |  View/Download:70/9  |  Submit date:2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Phenolic Compounds from Belamcanda chinensis Seeds 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 580
Authors:  Song, Ying-Ying;  Liu, Ying;  Yan, Yong-Ming;  Lu, Xi-Feng;  Cheng, Yong-Xian
View  |  Adobe PDF(1350Kb)  |  Favorite  |  View/Download:48/5  |  Submit date:2018/07/02
Belamcanda Chinensis  Belamcanosides a And b  Gc Analysis  Hmgcr  Sqle  Ldlr  Sort1  
Structural analysis and biological activity of a highly regular glycosaminoglycan from Achatina fulica 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 181, 页码: 433-441
Authors:  Liu, Jie;  Zhou, Lutan;  He, Zhicheng;  Gao, Na;  Shang, Feineng;  Xu, Jianping;  Li, Zi;  Yang, Zengming;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(2955Kb)  |  Favorite  |  View/Download:131/16  |  Submit date:2018/05/08
Snail  Glycosaminoglycan  Chemical Structure  Heparin  Anticoagulant