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One-Pot Assembly of the Highly Branched Tetradecasaccharide from Ganoderma lucidum Glycan GLSWA-1 with Immune-Enhancing Activities | |
Chen,Zhiyuan; Xiao,Guozhi | |
2023 | |
发表期刊 | ORGANIC LETTERS
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ISSN | 1523-7052 |
卷号 | 25期号:40页码:7395-7399 |
摘要 | The highly branched tetradecasaccharide repeating unit and shorter sequences of GLSWA-1 with immune-enhancing activities from Ganoderma lucidum have been prepared via a one-pot glycan assembly strategy. The synthetic route features (1) orthogonal one-pot glycosylation on the basis of PVB glycosylation to streamline glycan synthesis avoiding such issues as aglycone transfer, (2) one-pot assembly of oligosaccharides with up to four different glycosyl linkages, and (3) modular and convergent [4+5+5] one-pot assembly of the highly branched tetradecasaccharide. |
关键词 | CARBOHYDRATE VACCINES GLYCOSYLATION ALKYNYLBENZOATES POLYSACCHARIDES CATALYSIS |
DOI | 10.1021/acs.orglett.3c02898 |
收录类别 | SCI |
WOS记录号 | WOS:001084877100001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/75280 |
专题 | 中国科学院昆明植物研究所 |
推荐引用方式 GB/T 7714 | Chen,Zhiyuan,Xiao,Guozhi. One-Pot Assembly of the Highly Branched Tetradecasaccharide from Ganoderma lucidum Glycan GLSWA-1 with Immune-Enhancing Activities[J]. ORGANIC LETTERS,2023,25(40):7395-7399. |
APA | Chen,Zhiyuan,&Xiao,Guozhi.(2023).One-Pot Assembly of the Highly Branched Tetradecasaccharide from Ganoderma lucidum Glycan GLSWA-1 with Immune-Enhancing Activities.ORGANIC LETTERS,25(40),7395-7399. |
MLA | Chen,Zhiyuan,et al."One-Pot Assembly of the Highly Branched Tetradecasaccharide from Ganoderma lucidum Glycan GLSWA-1 with Immune-Enhancing Activities".ORGANIC LETTERS 25.40(2023):7395-7399. |
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