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One-Pot Assembly of the Highly Branched Tetradecasaccharide from Ganoderma lucidum Glycan GLSWA-1 with Immune-Enhancing Activities
Chen,Zhiyuan; Xiao,Guozhi
2023
发表期刊ORGANIC LETTERS
ISSN1523-7052
卷号25期号:40页码:7395-7399
摘要The highly branched tetradecasaccharide repeating unit and shorter sequences of GLSWA-1 with immune-enhancing activities from Ganoderma lucidum have been prepared via a one-pot glycan assembly strategy. The synthetic route features (1) orthogonal one-pot glycosylation on the basis of PVB glycosylation to streamline glycan synthesis avoiding such issues as aglycone transfer, (2) one-pot assembly of oligosaccharides with up to four different glycosyl linkages, and (3) modular and convergent [4+5+5] one-pot assembly of the highly branched tetradecasaccharide.
关键词CARBOHYDRATE VACCINES GLYCOSYLATION ALKYNYLBENZOATES POLYSACCHARIDES CATALYSIS
DOI10.1021/acs.orglett.3c02898
收录类别SCI
WOS记录号WOS:001084877100001
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/75280
专题中国科学院昆明植物研究所
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Chen,Zhiyuan,Xiao,Guozhi. One-Pot Assembly of the Highly Branched Tetradecasaccharide from Ganoderma lucidum Glycan GLSWA-1 with Immune-Enhancing Activities[J]. ORGANIC LETTERS,2023,25(40):7395-7399.
APA Chen,Zhiyuan,&Xiao,Guozhi.(2023).One-Pot Assembly of the Highly Branched Tetradecasaccharide from Ganoderma lucidum Glycan GLSWA-1 with Immune-Enhancing Activities.ORGANIC LETTERS,25(40),7395-7399.
MLA Chen,Zhiyuan,et al."One-Pot Assembly of the Highly Branched Tetradecasaccharide from Ganoderma lucidum Glycan GLSWA-1 with Immune-Enhancing Activities".ORGANIC LETTERS 25.40(2023):7395-7399.
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