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Steroidal alkaloid with unprecedented triheterocyclic architecture 期刊论文
CHEMICAL COMMUNICATIONS, 2023, 卷号: 59, 期号: 3, 页码: 326-329
作者:  Zhou,Zhong-Shun;  Zhao,Yun-Li;  Hu,Bin-Yuan;  Wang,Bei;  Liu,Ya-Ping;  Zhu,Yan-Yan;  He,Ying-Jie;  Wang,Zhao-Jie;  Dai,Zhi;  Zhao,Li-Xing;  Luo,Xiao-Dong
浏览  |  Adobe PDF(975Kb)  |  收藏  |  浏览/下载：15/3  |  提交时间：2024/07/22
MALIC-ACID  SKELETON  
Dimeric benzylisoquinoline alkaloids from Thalictrum delavayi and their biological activities 期刊论文
FITOTERAPIA, 2023, 卷号: 164, 页码: 105356
作者:  Jin,Qiong;  Qin,Xu-Jie;  Dai,Zhi;  Zhao,Yun;  Zhu,Yan-Yan;  Chen,Shan-Shan;  Liu,Ya-Ping;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1861Kb)  |  收藏  |  浏览/下载：8/3  |  提交时间：2024/07/25
Thalictrum delavayi  Ranunculaceae  Bisbenzylisoquinoline alkaloids  Cytotoxicities  Immunosuppressive effects  CYCLOARTANE GLYCOSIDES  APORPHINE  LEAVES  PLANTS  
Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载：52/13  |  提交时间：2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
作者:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
收藏  |  浏览/下载：76/0  |  提交时间：2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 1, 页码: 127-135
作者:  Zhao,Yun-Li;  Gou,Zhong-Ping;  Shang,Jian-Hua;  Li,Wan-Yi;  Kuang,Yu;  Li,Ming-Yuan;  Luo,Xiao-Dong
浏览  |  Adobe PDF(958Kb)  |  收藏  |  浏览/下载：130/48  |  提交时间：2022/04/02
Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
作者:  Zhu,Pei-Feng;  Cheng,Gui-Guang;  Zhao,Lan-Qin;  Khan,Afsar;  Yang,Xing-Wei;  Zhang,Bu-Yun;  Li,Meng-Cheng;  Liu,Ya-Ping;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2113Kb)  |  收藏  |  浏览/下载：126/40  |  提交时间：2022/04/02
Rhynchanthus beesianus  diarylheptanoid  antioxidant activity  intracellular reactive oxygen species  cell apoptosis  GINGER ZINGIBER-OFFICINALE  PC12 CELLS  RHIZOMES  NEUROPROTECTION  ACTIVATION  ENZYMES  L.  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
浏览  |  Adobe PDF(5546Kb)  |  收藏  |  浏览/下载：134/46  |  提交时间：2022/04/02
Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：172/89  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 267, 页码: 113506
作者:  Zhao,Yun-Li;  Pu,Shi-Biao;  Qi,Yan;  Wu,Bai-Fen;  Shang,Jian-Hua;  Liu,Ya-Ping;  Hu,Di;  Luo,Xiao-Dong
浏览  |  Adobe PDF(9993Kb)  |  收藏  |  浏览/下载：105/34  |  提交时间：2022/04/02
Alstonia scholaris  Indole alkaloids  Pulmonary fibrosis  Picrinine  Vallesamine  Scholaricine  19-Epischolaricine  FLIGHT MASS-SPECTROMETRY  ACUTE LUNG INJURY  AIRWAY INFLAMMATION  OXIDATIVE STRESS  BARK EXTRACTS  LEAVES  CONSTITUENTS  COLLAGEN  LEAF  KL-6  
Exploring Aporphine as Anti-inflammatory and Analgesic Lead from Dactylicapnos scandens 期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 1, 页码: 257-260
作者:  Wang, Bei;  Zhao, Yin-Jiao;  Zhao, Yun-Li;  Liu, Ya-Ping;  Li, Xiao-Nian;  Zhang, Hongbin;  Luo, Xiao-Dong
收藏  |  浏览/下载：142/0  |  提交时间：2020/03/18