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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
Authors:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
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glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Novel dual-color drug screening model for GLUT4 translocation in adipocytes 期刊论文
MOLECULAR AND CELLULAR PROBES, 2019, 卷号: 43, 页码: 6-12
Authors:  Lu, Yanting;  Ma, Xiuli;  Kong, Qinghua;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Qin, Wanying;  Wang, Libin;  Xiong, Wenyong
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GLUT4  pHluorin  Screening  Glucose uptake  
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
Authors:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
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adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
Authors:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
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Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
一种防治脂肪肝和肥胖的药物及其在制药中的应用 专利
申请日期: 2017-01-24, 公开日期: 2017-06-13
Inventors:  刘吉开;  熊文勇;  许宇辉;  逯艳婷;  王芳
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Pyrocincholic acid 3beta-O-beta-D-quinovopyranosyl-28-O-beta-D-glucopyranoside suppresses adipogenesis and regulates lipid metabolism in 3T3-L1 adipocytes. 期刊论文
Natural products and bioprospecting, 2017, 卷号: 7, 期号: 3, 页码: 225-234
Authors:  Peng, Li;  Lu, Yanting;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Zhang, Yumei;  Xiong, Wenyong
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Chemical constituents from fruiting bodies of Basidiomycete Perenniporia subacida 期刊论文
FITOTERAPIA, 2016, 卷号: 109, 页码: 179-184
Authors:  Wen, Chun-Nan;  Hu, Dong-Bao;  Bai, Xue;  Wang, Fang;  Li, Zheng-Hui;  Feng, Tao;  Liu, Ji-Kai
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Perenniporia Subacida  Abietane Diterpenoids  Antifungal Activities  Cytotoxic Activities  
化合物Antroalbol H及其药物组合物和其制备方法与应用 专利
专利类型: 发明, 专利号: CN201610003454.3, 申请日期: 2016-01-04, 公开日期: 2016-05-11
Inventors:  刘吉开;  熊文勇;  王芳;  杨晓艳
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Clerodane Diterpenoids with Anti-hyperglycemic Activity from Tinospora crispa. 期刊论文
Natural products and bioprospecting, 2016, 卷号: 6, 期号: 5, 页码: 247-255
Authors:  Gao, Yuan;  Niu, Yan-Fen;  Wang, Fei;  Hai, Ping;  Wang, Fang;  Fang, Yin-Dong;  Xiong, Wen-Yong;  Liu, Ji-Kai
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AS160 controls eukaryotic cell cycle and proliferation by regulating the CDK inhibitor p21 期刊论文
CELL CYCLE, 2016, 卷号: 15, 期号: 13, 页码: 1733-1741
Authors:  Gongpan, Pianchou;  Lu, Yanting;  Wang, Fang;  Xu, Yuhui;  Xiong, Wenyong
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As160/tbc1d4  Cell Cycle  Cell Proliferation  G1/s  P21