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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
Authors:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
Favorite  |  View/Download:7/0  |  Submit date:2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Novel dual-color drug screening model for GLUT4 translocation in adipocytes 期刊论文
MOLECULAR AND CELLULAR PROBES, 2019, 卷号: 43, 页码: 6-12
Authors:  Lu, Yanting;  Ma, Xiuli;  Kong, Qinghua;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Qin, Wanying;  Wang, Libin;  Xiong, Wenyong
Favorite  |  View/Download:50/0  |  Submit date:2019/03/18
GLUT4  pHluorin  Screening  Glucose uptake  
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
Authors:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
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adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
Single glucose molecule transport process revealed by force tracing and molecular dynamics simulations 期刊论文
NANOSCALE HORIZONS, 2018, 卷号: 3, 期号: 5, 页码: 9
Authors:  Pan, Yangang;  Zhang, Yuebin;  Gongpan, Pianchou;  Zhang, Qingrong;  Huang, Siteng;  Wang, Bin;  Xu, Bingqian;  Shan, Yuping;  Xiong, Wenyong;  Li, Guohui;  Wang, Hongda
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Mechanistic insights into GLUT1 activation and clustering revealed by super-resolution imaging 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 27, 页码: 7033-7038
Authors:  Yan, Qiuyan;  Lu, Yanting;  Zhou, Lulu;  Chen, Junling;  Xu, Haijiao;  Cai, Mingjun;  Shi, Yan;  Jiang, Junguang;  Xiong, Wenyong;  Gao, Jing;  Wang, Hongda
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Inhibition of 3,5,2 ',4 '-Tetrahydroxychalcone on Production of Uric Acid in Hypoxanthine-Induced Hyperuricemic Mice 期刊论文
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2018, 卷号: 41, 期号: 1, 页码: 99-105
Authors:  Niu, Yanfen;  Zhou, Yuanfang;  Lin, Hua;  Gao, Li-Hui;  Xiong, Wenyong;  Zhu, Huajie;  Zou, Cheng-Gang;  Li, Ling
Favorite  |  View/Download:37/0  |  Submit date:2018/05/08
Purine Metabolism Enzyme  3  Hyperuricemia  5  2 '  4 '-tetrahydroxychalcone  
Mechanistic insights into GLUT1 activation and clustering revealed by super-resolution imaging 期刊论文
pnas, 2018, 页码: 1
Authors:  Qiuyan Yan;  Yanting Lu;  Lulu Zhou;  Junling Chen;  Haijiao Xu;  Mingjun Cai;  Yan Sh;  Junguang Jiang;  Wenyong Xiong;  Jing Gao;  Hongda Wang
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Old drug, new indication: Olsalazine sodium reduced serum uric acid levels in mice via inhibiting xanthine oxidoreductase activity 期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2017, 卷号: 135, 期号: 3, 页码: 114-120
Authors:  Niu, Yanfen;  Li, Hongjian;  Gao, Lihui;  Lin, Hua;  Kung, Hsiangfu;  Lin, Marie Chia-mi;  Leung, Kwong-Sak;  Wong, Man-Hon;  Xiong, Wenyong;  Li, Ling
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Olsalazine Sodium  Hyperuricemia  Xanthine Oxidase  Uric Acid  
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
Authors:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
View  |  Adobe PDF(4940Kb)  |  Favorite  |  View/Download:164/12  |  Submit date:2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
一种调节脂代谢和肥胖的化合物PAQG在制药中的应用 专利
申请日期: 2017-04-21, 公开日期: 2017-08-01
Inventors:  熊文勇;  张玉梅;  彭莉;  胡敬
Favorite  |  View/Download:31/0  |  Submit date:2018/05/10