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Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
Authors:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
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Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
Authors:  Su,Lihua;  Zhang,Xintian;  Ma,Yunbao;  Geng,Changan;  Huang,Xiaoyan;  Hu,Jing;  Li,Tianze;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xuemei;  Chen,Ji-Jun
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Guaianolide dimers  Artematrolides AeR  Artemisia atrovirens  Cytotoxicity  Cell cycle  Apoptosis  FARNESYL-PROTEIN TRANSFERASE  CELL-CYCLE ARREST  HEPATOCELLULAR-CARCINOMA  GUAIANOLIDES  LACTONES  INHIBITORS  ARTEMINOLIDE  APOPTOSIS  ARGYI  HELA  
Trimeric and dimeric sesquiterpenoids from Artemisia atrovirens and their cytotoxicities 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2021, 卷号: 8, 期号: 6, 页码: 1249-1256
Authors:  Su,Li-Hua;  Li,Tian-Ze;  Geng,Chang-An;  Ma,Yun-Bao;  Huang,Xiao-Yan;  Wang,Jin-Ping;  Zhang,Xue-Mei;  Chen,Ji-Jun
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Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
Authors:  Liu,Yan;  Luo,Shi-Hong;  Hua,Juan;  Li,De-Sen;  Ling,Yi;  Luo,Qian;  Li,Sheng-Hong
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cadinenes  defensive chemicals  Eupatorium adenophorum  sesquiterpenes  sesquiterpene synthase  NATURAL-PRODUCTS  FUNCTIONAL-CHARACTERIZATION  ABSOLUTE STEREOCHEMISTRY  TERPENE SYNTHASES  EXPRESSION  CLONING  EMISSION  LEAVES  GENES  9-OXO-10,11-DEHYDROAGERAPHORONE  
The untapped potential of plant sesterterpenoids: chemistry, biological activities and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2021, 卷号: 38, 期号: 12, 页码: 2293-2314
Authors:  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
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LEUCOSCEPTRUM-CANUM  GLANDULAR TRICHOMES  FERN CONSTITUENTS  AERIAL PARTS  ABSOLUTE STEREOCHEMISTRY  SALVIA  CYCLIZATION  SYNTHASES  NORSESTERTERPENES  CONFIGURATION  
Hypermonones A-I, New Polyprenylated Acylphloroglucinols from Hypericum monogynum with Multidrug Resistance Reversal Activity 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 9, 页码: 2422-2432
Authors:  Zeng,Yan-Rong;  Li,Ya-Nan;  Yang,Jue;  Yi,Ping;  Huang,Lei;  Huang,Lie-Jun;  Gu,Wei;  Hu,Zhan-Xing;  Li,Yan-Mei;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
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Hypericum monogynum  Phytochemistry  Structure elucidation  Biological activity  Multidrug resistance reversal activity  P-GLYCOPROTEIN  MODULATORS  CANCER  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
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Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Functional triterpenoids from medicinal fungi Ganoderma applanatum: A continuous search for antiadipogenic agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104977
Authors:  Su,Hai-Guo;  Wang,Qian;  Zhou,Lin;  Peng,Xing-Rong;  Xiong,Wen-Yong;  Qiu,Ming -Hua
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Ganoderma applanatum  Lanostane triterpenoids  Antiadipogenic effects  LANOSTANE-TYPE TRITERPENOIDS  ACID  
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
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enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
Authors:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
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Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA