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PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
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mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
Authors:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
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Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
High-quality evergreen azalea genome reveals tandem duplication-facilitated low-altitude adaptability and floral scent evolution 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 期号: 12, 页码: 2544-2560
Authors:  Wang,Xiuyun;  Gao,Yuan;  Wu,Xiaopei;  Wen,Xiaohui;  Li,Danqing;  Zhou,Hong;  Li,Zheng;  Liu,Bing;  Wei,Jianfen;  Chen,Fei;  Chen,Feng;  Zhang,Chengjun;  Zhang,Liangsheng;  Xia,Yiping
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Azalea  Rhododendron ovatum  altitude  adaptability  floral scent  terpene synthase (TPS)  tandem duplication  defence response  PHYLOGENETIC ANALYSIS  TERPENE SYNTHASES  PLANT VOLATILES  SALICYLIC-ACID  JASMONIC ACID  WHOLE-GENOME  GENE  DIVERSITY  TOOL  TRANSCRIPTOME  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
Authors:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
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FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
Impact of titanium dioxide nanoparticles on intestinal community in 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced acute colitis mice and the intervention effect of vitamin E 期刊论文
NANOSCALE, 2021, 卷号: 13, 期号: 3, 页码: 1842-1862
Authors:  Gao,Yanjun;  Li,Tingyu;  Duan,Shumin;  Lyu,Lizhi;  Li,Yuan;  Xu,Lin;  Wang,Yun
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GUT MICROBIOTA  GLUTAMINE-SYNTHETASE  ULCERATIVE-COLITIS  INFLAMMATION  METABOLISM  FOOD  ANTIOXIDANT  TRYPTOPHAN  BUTYRATE  PROTECTS  
Specialised metabolites as chemotaxonomic markers of Coptosapelta diffusa, supporting its delimitation as sisterhood phylogenetic relationships with Rubioideae 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 192, 页码: 112929
Authors:  Gao,Rong-Rong;  Liu,Zhi-Fang;  Yang,Xue-Fei;  Song,Yu-Liang;  Cui,Xiao-Yun;  Yang,Ji-Yuan;  Lu,Chun-Hua;  Shen,Yue-Mao
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Coptosapelta diffusa  Rubiaceae  Phytochemical investigation  Seco-iridoid glucosides  Guaiane-type sesquiterpenes  GUAIANE SESQUITERPENOIDS  ABSOLUTE-CONFIGURATION  SECONDARY METABOLITES  IRIDOID GLYCOSIDES  FATTY-ACID  FAMILY  THYSANOSPERMUM  ANTHRAQUINONES  CONSTITUENTS  ASSIGNMENT  
Spatiotemporal maintenance of flora in the Himalaya biodiversity hotspot: Current knowledge and future perspectives 期刊论文
ECOLOGY AND EVOLUTION, 2021, 卷号: 11, 期号: 16, 页码: 10794-10812
Authors:  Wambulwa,Moses C.;  Milne,Richard;  Wu,Zeng-Yuan;  Spicer,Robert A.;  Provan,Jim;  Luo,Ya-Huang;  Zhu,Guang-Fu;  Wang,Wan-Ting;  Wang,Hong;  Gao,Lian-Ming;  Li,De-Zhu;  Liu,Jie
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biodiversity hotspot  climate change  elevational gradient  Himalayan flora  mountain ecosystem  spatiotemporal diversification  SPECIES RICHNESS PATTERNS  QINGHAI-TIBET PLATEAU  SOUTH ASIAN MONSOON  ELEVATIONAL GRADIENT  HENGDUAN MOUNTAINS  CLIMATE-CHANGE  BETA-DIVERSITY  QUATERNARY GLACIATION  GENETIC CONSEQUENCES  ARTIFICIAL DISPERSAL  
The Chromosome-Based Rubber Tree Genome Provides New Insights into Spurge Genome Evolution and Rubber Biosynthesis 期刊论文
MOLECULAR PLANT, 2020, 卷号: 13, 期号: 2, 页码: 336-350
Authors:  Liu, Jin;  Shi, Cong;  Shi, Cheng-Cheng;  Li, Wei;  Zhang, Qun-Jie;  Zhang, Yun;  Li, Kui;  Lu, Hui-Fang;  Shi, Chao;  Zhu, Si-Tao;  Xiao, Zai-Yun;  Nan, Hong;  Yue, Yao;  Zhu, Xun-Ge;  Wu, Yu;  Hong, Xiao-Ning;  Fan, Guang-Yi;  Tong, Yan;  Zhang, Dan;  Mao, Chang-Li;  Liu, Yun-Long;  Hao, Shi-Jie;  Liu, Wei-Qing;  Lv, Mei-Qi;  Zhang, Hai-Bin;  Liu, Yuan;  Hu-tang, Ge-Ran;  Wang, Jin-Peng;  Wang, Jia-Hao;  Sun, Ying-Huai;  Ni, Shu-Bang;  Chen, Wen-Bin;  Zhang, Xing-Cai;  Jiao, Yuan-Nian;  Eichler, Evan E.;  Li, Guo-Hua;  Liu, Xin;  Gao, Li-Zhi
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rubber tree  rubber biosynthesis  chromosome evolution  whole-genome duplication  domestication  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
Authors:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
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Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii 期刊论文
FITOTERAPIA, 2020, 卷号: 140, 页码: 6
Authors:  Jin, Qiong;  Wei, Xin;  Qin, Xu-Jie;  Gao, Fei;  Zhu, Pei-Feng;  Yuan, Hai-Lian;  Njateng, Guy Sedar Singor;  Dai, Zhi;  Liu, Ya-Ping;  Luo, Xiao-Dong
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seco-aporphine derivatives  Immunosuppressive bioactivity  Thalictrum wangii