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Inhibition of 3,5,2 ',4 '-Tetrahydroxychalcone on Production of Uric Acid in Hypoxanthine-Induced Hyperuricemic Mice 期刊论文
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2018, 卷号: 41, 期号: 1, 页码: 99-105
Authors:  Niu, Yanfen;  Zhou, Yuanfang;  Lin, Hua;  Gao, Li-Hui;  Xiong, Wenyong;  Zhu, Huajie;  Zou, Cheng-Gang;  Li, Ling
Favorite  |  View/Download:37/0  |  Submit date:2018/05/08
Purine Metabolism Enzyme  3  Hyperuricemia  5  2 '  4 '-tetrahydroxychalcone  
老药新用:奥柳氮钠的降尿酸作用及分子机制研究 学位论文
: 中国科学院大学, 2017
Authors:  牛艳芬
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Old drug, new indication: Olsalazine sodium reduced serum uric acid levels in mice via inhibiting xanthine oxidoreductase activity 期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2017, 卷号: 135, 期号: 3, 页码: 114-120
Authors:  Niu, Yanfen;  Li, Hongjian;  Gao, Lihui;  Lin, Hua;  Kung, Hsiangfu;  Lin, Marie Chia-mi;  Leung, Kwong-Sak;  Wong, Man-Hon;  Xiong, Wenyong;  Li, Ling
Favorite  |  View/Download:24/0  |  Submit date:2018/05/08
Olsalazine Sodium  Hyperuricemia  Xanthine Oxidase  Uric Acid  
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
Authors:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
View  |  Adobe PDF(4940Kb)  |  Favorite  |  View/Download:164/12  |  Submit date:2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
一种防治糖尿病和高脂血症的药物及其在制药中的应用 专利
申请日期: 2017-01-24, 公开日期: 2017-06-13
Inventors:  熊文勇;  刘吉开;  许宇辉;  牛艳芬;  胡敬
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RACK1 is required for adipogenesis 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 卷号: 311, 期号: 5, 页码: C831-C836
Authors:  Kong, Qinghua;  Gao, Lan;  Niu, Yanfen;  Gongpan, Pianchou;  Xu, Yuhui;  Li, Yan;  Xiong, Wenyong
View  |  Adobe PDF(1017Kb)  |  Favorite  |  View/Download:154/11  |  Submit date:2017/02/14
Rack1  3t3-l1  Adipogenesis  Wnt  Pi3k-akt-mtor-s6k  
Hypouricaemic action of mangiferin results from metabolite norathyriol via inhibiting xanthine oxidase activity 期刊论文
PHARMACEUTICAL BIOLOGY, 2016, 卷号: 54, 期号: 9, 页码: 1680-1686
Authors:  Niu, Yanfen;  Liu, Jia;  Liu, Hai-Yang;  Gao, Li-Hui;  Feng, Guo-Hua;  Liu, Xu;  Li, Ling
View  |  Adobe PDF(1241Kb)  |  Favorite  |  View/Download:56/3  |  Submit date:2017/01/05
Active Metabolite  Hyperuricaemia  Structure-activity Relationship  Uric Acid Production  
Mangiferin and its aglycone, norathyriol, improve glucose metabolism by activation of AMP-activated protein kinase 期刊论文
PHARMACEUTICAL BIOLOGY, 2014, 卷号: 52, 期号: 1, 页码: 68-73
Authors:  Wang, Fang;  Yan, Juming;  Niu, Yanfen;  Li, Yan;  Lin, Hua;  Liu, Xu;  Liu, Jikai;  Li, Ling
View  |  Adobe PDF(383Kb)  |  Favorite  |  View/Download:164/23  |  Submit date:2014/04/09
Active Metabolite  Ampk  Insulin Resistance  L6 Muscle Cells  Norathyriol  
Management and land use change effects on soil carbon in northern China's grasslands: a synthesis 期刊论文
AGRICULTURE ECOSYSTEMS & ENVIRONMENT, 2011, 卷号: 142, 期号: 3-4, 页码: 329-340
Authors:  Wang, Shiping;  Wilkes, Andreas;  Zhang, Zhicai;  Chang, Xiaofeng;  Lang, Rong;  Wang, Yanfen;  Niu, Haishan
Adobe PDF(908Kb)  |  Favorite  |  View/Download:314/79  |  Submit date:2012/04/10
Carbon Sequestration  Grasslands  Land Use Change  Grazing  Cultivation  Pasture  
3,5,2 ',4 '-Tetrahydroxychalcone, a new non-purine xanthine oxidase inhibitor 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2011, 卷号: 189, 期号: 3, 页码: 161-166
Authors:  Niu, Yanfen;  Zhu, Huajie;  Liu, Jia;  Fan, Huafang;  Sun, Ling;  Lu, Wei;  Liu, Xu;  Li, Ling
Adobe PDF(507Kb)  |  Favorite  |  View/Download:363/176  |  Submit date:2012/04/10
Xanthine Oxidase  3  Hyperuricemia  5  Uric Acid  2 '  4 '-tetrahydroxychalcone