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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
Authors:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
Favorite  |  View/Download:2/0  |  Submit date:2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Novel dual-color drug screening model for GLUT4 translocation in adipocytes 期刊论文
MOLECULAR AND CELLULAR PROBES, 2019, 卷号: 43, 页码: 6-12
Authors:  Lu, Yanting;  Ma, Xiuli;  Kong, Qinghua;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Qin, Wanying;  Wang, Libin;  Xiong, Wenyong
Favorite  |  View/Download:49/0  |  Submit date:2019/03/18
GLUT4  pHluorin  Screening  Glucose uptake  
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
Authors:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
Favorite  |  View/Download:86/0  |  Submit date:2019/03/18
adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells 期刊论文
ANGIOGENESIS, 2018, 卷号: 21, 期号: 4, 页码: 849-860
Authors:  Liang, Huichun;  Ge, Fei;  Xu, Yuhui;  Xiao, Ji;  Zhou, Zhongmei;  Liu, Rong;  Chen, Ceshi
Favorite  |  View/Download:229/0  |  Submit date:2018/12/03
MiR-153  Angiopoietin 1  Endothelial cell  Tumor angiogenesis  Breast cancer  
Borapetoside E 对高脂饮食诱导小鼠糖脂代谢的影响及其机制研究 学位论文
: 中国科学院大学, 2017
Authors:  许宇辉
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Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
Authors:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
View  |  Adobe PDF(4940Kb)  |  Favorite  |  View/Download:161/11  |  Submit date:2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
一种防治糖尿病和高脂血症的药物及其在制药中的应用 专利
申请日期: 2017-01-24, 公开日期: 2017-06-13
Inventors:  熊文勇;  刘吉开;  许宇辉;  牛艳芬;  胡敬
Favorite  |  View/Download:78/0  |  Submit date:2018/05/10
一种防治脂肪肝和肥胖的药物及其在制药中的应用 专利
申请日期: 2017-01-24, 公开日期: 2017-06-13
Inventors:  刘吉开;  熊文勇;  许宇辉;  逯艳婷;  王芳
Favorite  |  View/Download:73/0  |  Submit date:2018/05/10
Pyrocincholic acid 3beta-O-beta-D-quinovopyranosyl-28-O-beta-D-glucopyranoside suppresses adipogenesis and regulates lipid metabolism in 3T3-L1 adipocytes. 期刊论文
Natural products and bioprospecting, 2017, 卷号: 7, 期号: 3, 页码: 225-234
Authors:  Peng, Li;  Lu, Yanting;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Zhang, Yumei;  Xiong, Wenyong
Favorite  |  View/Download:5/0  |  Submit date:2019/03/29
RACK1 is required for adipogenesis 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 卷号: 311, 期号: 5, 页码: C831-C836
Authors:  Kong, Qinghua;  Gao, Lan;  Niu, Yanfen;  Gongpan, Pianchou;  Xu, Yuhui;  Li, Yan;  Xiong, Wenyong
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Rack1  3t3-l1  Adipogenesis  Wnt  Pi3k-akt-mtor-s6k