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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
Authors:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
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glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Aurovertin B sensitizes colorectal cancer cells to NK cell recognition and lysis 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 503, 期号: 4, 页码: 3057-3063
Authors:  Zhu, Huifang;  Wang, Fei;  Ju, Xiaoman;  Kong, Lingmei;  An, Tao;  Zhao, Zhangxun;  Liu, Jikai;  Li, Yan
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Aurovertin B  Cytotoxicity  Immunotherapy  NK cell  NKG2D ligands  
Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 17, 页码: 10158-10165
Authors:  Zhang, Shuaibing;  Huang, Ying;  He, Shijun;  Chen, Heping;  Wu, Bin;  Li, Shanyong;  Zhao, Zhenzhu;  Li, Zhenghui;  Wang, Xian;  Zuo, Jianping;  Feng, Tao;  Liu, Jikai
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一种混源萜二聚体类化合物及其药物组合物和其应用 专利
申请日期: 2018-08-01, 公开日期: 2018-11-27
Inventors:  白雪;  刘吉开;  姚建能;  孔清华
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Digestibility of fucosylated glycosaminoglycan from sea cucumber and its effects on digestive enzymes under simulated salivary and gastrointestinal conditions 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 186, 页码: 217-225
Authors:  Zhao, Longyan;  Qin, Yujing;  Guan, Ruowei;  Zheng, Wenqi;  Liu, Jikai;  Zhao, Jinhua
Favorite  |  View/Download:65/0  |  Submit date:2018/05/08
Sea Cucumber  Polysaccharide  Fucosylated Glycosaminoglycan  In Vitro Digestion  Digestive Enzyme  
Enzyme-Assisted Extraction Optimization, Characterization and Antioxidant Activity of Polysaccharides from Sea Cucumber Phyllophorus proteus 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 590
Authors:  Qin, Yujing;  Yuan, Qingxia;  Zhang, Yuexing;  Li, Jialu;  Zhu, Xinjiao;  Zhao, Lingling;  Wen, Jing;  Liu, Jikai;  Zhao, Longyan;  Zhao, Jinhua
View  |  Adobe PDF(5270Kb)  |  Favorite  |  View/Download:95/12  |  Submit date:2018/07/02
Sea Cucumber  Polysaccharide  Enzyme-assisted Extraction  Characterization  Antioxidant Activity  
微酸多年卧孔菌化学成分的研究 期刊论文
中成药, 2018, 卷号: 40, 期号: 01, 页码: 129-133
Authors:  郭怀宇;  王国凯;  刘吉开;  王刚
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微酸多年卧孔菌  化学成分  分离鉴定  
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
Authors:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
View  |  Adobe PDF(4940Kb)  |  Favorite  |  View/Download:164/12  |  Submit date:2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production 期刊论文
MOLECULAR CARCINOGENESIS, 2017, 卷号: 56, 期号: 5, 页码: 1414-1426
Authors:  Yu, Xinfang;  Li, Wei;  Deng, Qipan;  You, Shuo;  Liu, Haidan;  Peng, Songling;  Liu, Xiaolan;  Lu, Jingchen;  Luo, Xiangjian;  Yang, Lifang;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Liu, Wenbin;  Wu, Shengqi;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
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Angiogenesis  Breast Cancer  Egfr  Neoalbaconol  Vegf  
一种防治糖尿病和高脂血症的药物及其在制药中的应用 专利
申请日期: 2017-01-24, 公开日期: 2017-06-13
Inventors:  熊文勇;  刘吉开;  许宇辉;  牛艳芬;  胡敬
Favorite  |  View/Download:79/0  |  Submit date:2018/05/10