Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities

doi:10.1016/j.tet.2020.131783

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	Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities
	Shi,Bao-Bao ; Wang,Fang ; Chen,Gao ; Schinnerl,Johann ; Zeng,Ying ; Cai,Xiang-Hai
	2021
Source Publication	TETRAHEDRON
ISSN	0040-4020
Volume	79 Pages:131783
Abstract	A carefully performed phytochemical investigation of the roots of Stemona mairei (Stemonaceae) led to the discovery of six so far undescribed dihydrostilbene dimers maistilbene A-F and four monomers maistilbene G-J. This is the first report of stilbenoids of this plant species and the first report of dimeric dihydrostilbenes from this plant family. The absolute configuration of these compounds was determined by a combination of Mo-2(AcO)(4)-induced ECD spectra and quantum chemical calculation of NMR chemical shift, ECD and spin-spin coupling constants. Maistilbene G could increase the glucose consumption in L6 myotubes, disclosing a new hypoglycemic candidate. (C) 2020 Elsevier Ltd. All rights reserved.
Keyword	Stemona mairei Dihydrostilbenes Structure elucidation Quantum chemical calculation Hypoglycemic activity assay STILBENOIDS CONFIGURATION DERIVATIVES
DOI	10.1016/j.tet.2020.131783
WOS ID	WOS:000604923900001
Citation statistics	Cited Times:1[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/73093
Collection	中国科学院昆明植物研究所
Affiliation	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Key Lab Plant Divers & Biogeog East Asia, Kunming 650201, Yunnan, Peoples R China 4.Univ Vienna, Dept Systemat & Evolutionary Bot, Rennweg 14, A-1030 Vienna, Austria
Recommended Citation GB/T 7714	Shi,Bao-Bao,Wang,Fang,Chen,Gao,et al. Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities[J]. TETRAHEDRON,2021,79:131783.
APA	Shi,Bao-Bao,Wang,Fang,Chen,Gao,Schinnerl,Johann,Zeng,Ying,&Cai,Xiang-Hai.(2021).Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities.TETRAHEDRON,79,131783.
MLA	Shi,Bao-Bao,et al."Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities".TETRAHEDRON 79(2021):131783.

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