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Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
Authors:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
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Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
An anticoagulant fucan sulfate with hexasaccharide repeating units from the sea cucumber Holothuria albiventer 期刊论文
CARBOHYDRATE RESEARCH, 2018, 卷号: 464, 页码: 12-18
Authors:  Cai, Ying;  Yang, Wenjiao;  Yin, Ronghua;  Zhou, Lutan;  Li, Zhongkun;  Wu, Mingyi;  Zhao, Jinhua
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Fucan Sulfate  Chemical Structure  Anticoagulant  Polysaccharide  Sea Cucumber  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
Authors:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(3117Kb)  |  Favorite  |  View/Download:67/8  |  Submit date:2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Structural analysis and biological activity of a highly regular glycosaminoglycan from Achatina fulica 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 181, 页码: 433-441
Authors:  Liu, Jie;  Zhou, Lutan;  He, Zhicheng;  Gao, Na;  Shang, Feineng;  Xu, Jianping;  Li, Zi;  Yang, Zengming;  Wu, Mingyi;  Zhao, Jinhua
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Snail  Glycosaminoglycan  Chemical Structure  Heparin  Anticoagulant  
Plasma contact activation by a fucosylated chondroitin sulfate and its structure-activity relationship study 期刊论文
GLYCOBIOLOGY, 2018, 卷号: 28, 期号: 10, 页码: 754-764
Authors:  Lin, Lisha;  Xu, Li;  Xiao, Chuang;  Zhou, Lutan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
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Plasma contact activation by a fucosylated chondroitin sulfate and its structure-activity relationship study 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 10, 页码: 2429
Authors:  Lin, Lisha;  Xu, Li;  Xiao, Chuang;  Zhou, Lutan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
Favorite  |  View/Download:13/0  |  Submit date:2018/12/27
Interactions between depolymerized fucosylated glycosaminoglycan and coagulation proteases or inhibitors 期刊论文
THROMBOSIS RESEARCH, 2016, 卷号: 146, 页码: 59-68
Authors:  Xiao, Chuang;  Lian, Wu;  Zhou, Lutan;  Gao, Na;  Xua, Li;  Chen, Jun;  Wu, Mingyi;  Peng, Wenlie;  Zhao, Jinhua
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Fucosylated Glycosaminoglycan  Coagulation Proteases  Biolayer Interferometry  Binding Kinetics  Structure-activity Relationship  
dFG-53 药理药效学研究 学位论文
: 中国科学院大学, 2016
Authors:  周路坦
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Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 卷号: 112, 期号: 27, 页码: 8284-8289
Authors:  Zhao, Longyan;  Wu, Mingyi;  Xiao, Chuang;  Yang, Lian;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Chen, Jun;  Chen, Jianchao;  Liu, Jikai;  Qin, Hongbo;  Zhao, Jinhua
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Anticoagulant  Inhibitors  Oligosaccharides  Carbohydrates  Drug Discovery  
一种抑制内源性因子X酶活性的寡糖类化合物及其药物组合物 专利
专利类型: 发明, 专利号: CN201410549676.6, 申请日期: 2014-10-17, 公开日期: 2015-02-25
Inventors:  赵金华;  何金星;  吴明一;  赵龙岩;  刘峙汶;  杨莲;  李姿;  高娜;  肖创;  徐丽;  陈钧;  周路坦.
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