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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
浏览  |  Adobe PDF(17974Kb)  |  收藏  |  浏览/下载：69/19  |  提交时间：2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis 期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
作者:  Li,Sujuan;  Wang,Weili;  Lin,Lisha;  Yang,Lian;  Cai,Ying;  Yang,Xingzhi;  Zhang,Taocui;  Xiao,Chuang;  Yan,Hui;  Gao,Na;  Zhao,Jinhua
浏览  |  Adobe PDF(2610Kb)  |  收藏  |  浏览/下载：85/16  |  提交时间：2024/05/09
oligosaccharide  platelet activation  receptor  protease-activated  thrombin thrombosis  ANTIPLATELET THERAPIES  ALLOSTERIC LINKAGE  TISSUE FACTOR  PROTEASE  VORAPAXAR  MECHANISM  REVEALS  SITE  
Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata 期刊论文
MARINE DRUGS, 2023, 卷号: 21, 期号: 12, 页码: 632
作者:  Chen,Ru;  Wang,Weili;  Yin,Ronghua;  Pan,Ying;  Xu,Chen;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua;  Reyes,Fernando
浏览  |  Adobe PDF(6775Kb)  |  收藏  |  浏览/下载：81/24  |  提交时间：2024/05/09
aminoglycan  structural features  keratan sulfate  depolymerization  oligosaccharides  anticoagulant activity  INTRINSIC-FACTOR XASE  GLYCOSAMINOGLYCAN  OLIGOSACCHARIDES  DEPOLYMERIZATION  ELUCIDATION  DERIVATIVES  HEPARIN  
Structure characterization of a highly branched galactan from the slug Vaginulus alte and its utilization by human gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 236, 页码: 123935
作者:  Zuo,Zhichuang;  He,Zhicheng;  Ma,Yan;  Xu,Chen;  Tao,Xuelin;  Ning,Zimo;  Gao,Li;  Rehemiding,Ailainuer;  Gao,Na;  Zhao,Jinhua
浏览  |  Adobe PDF(4459Kb)  |  收藏  |  浏览/下载：48/6  |  提交时间：2024/07/30
Slug  Galactan  Chemical structure  Oligosaccharide  Human gut microbiota  SULFATED GALACTANS  HELIX-POMATIA  POLYSACCHARIDES  BIOACTIVITY  HYDROLYSIS  
Branched Chondroitin Sulfate Oligosaccharides Derived from the Sea Cucumber Acaudina molpadioides Stimulate Neurite Outgrowth 期刊论文
MARINE DRUGS, 2022, 卷号: 20, 期号: 10, 页码: 653
作者:  Wang, Weili;  Mao, Hui;  Li, Sujuan;  Zhang, Longlong;  Yang, Lian;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(5142Kb)  |  收藏  |  浏览/下载：52/13  |  提交时间：2024/04/30
fucosylated chondroitin sulfate  sea cucumber  disaccharide branch  oligosaccharide  neurite outgrowth  stimulation  HIPPOCAMPAL-NEURONS  PROMOTING ACTIVITY  GLYCOSAMINOGLYCAN  DISACCHARIDE  INHIBITOR  
Structural Characterization and Heparanase Inhibitory Activity of Fucosylated Glycosaminoglycan from Holothuria floridana 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 3, 页码: 162
作者:  Shi,Xiang;  Guan,Ruowei;  Zhou,Lutan;  Zuo,Zhichuang;  Tao,Xuelin;  Wang,Pin;  Zhou,Yanrong;  Yin,Ronghua;  Zhao,Longyan;  Gao,Na;  Zhao,Jinhua
收藏  |  浏览/下载：178/0  |  提交时间：2022/04/02
Holothuria floridana  fucosylated glycosaminoglycans  oligosaccharide  chemical structure  heparanase  
Five distinct fucan sulfates from sea cucumber Pattalus mollis: Purification, structural characterization and anticoagulant activities 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 186, 页码: 535-543
作者:  Ma,Yan;  Gao,Na;  Zuo,Zhichuang;  Li,Shanni;  Zheng,Wenqi;  Shi,Xiang;  Liu,Qipei;  Ma,Ting;  Yin,Ronghua;  Li,Xian;  Zhao,Jinhua
收藏  |  浏览/下载：133/0  |  提交时间：2022/04/02
Sea cucumber  Fucan sulfate  Chemical structure  Anticoagulant  Pattalus mollis  FUCOSYLATED GLYCOSAMINOGLYCAN  REPEATING UNIT  FUCOIDAN  POLYSACCHARIDES  ELUCIDATION  OLIGOSACCHARIDES  SPECTROSCOPY  
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
作者:  Li,Shanni;  Zhong,Wei;  Pan,Ying;  Lin,Lisha;  Cai,Ying;  Mao,Hui;  Zhang,Taocui;  Li,Sujuan;  Chen,Ru;  Zhou,Lutan;  Wang,Weili;  Cui,Qinghua;  Yin,Ronghua;  Huang,Shengxiong;  Zhao,Jinhua
浏览  |  Adobe PDF(2581Kb)  |  收藏  |  浏览/下载：272/36  |  提交时间：2022/04/02
Disaccharide branch  Fucosylated glycosaminoglycan  Holothuria nobilis  Oligosaccharide  Anticoagulant  INTRINSIC TENASE COMPLEX  CHONDROITIN SULFATE  ACAUDINA-MOLPADIOIDEA  FACTOR XASE  HEPARIN  DEPOLYMERIZATION  OLIGOSACCHARIDES  POLYSACCHARIDES  DERIVATIVES  
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
作者:  Chen,Ru;  Yin,Ronghua;  Li,Shanni;  Pan,Ying;  Mao,Hui;  Cai,Ying;  Lin,Lisha;  Wang,Weili;  Zhang,Taocui;  Zhou,Lutan;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua
浏览  |  Adobe PDF(3356Kb)  |  收藏  |  浏览/下载：141/36  |  提交时间：2022/04/02
Fucosylated glycosaminoglycan  Free radical depolymerization  Chemical structure  Oligosaccharide  NMR  INTRINSIC TENASE COMPLEX  ANTICOAGULANT ACTIVITIES  SEA-CUCUMBER  CHONDROITIN SULFATE  PHYSICOCHEMICAL CHARACTERISTICS  FACTOR XASE  POLYSACCHARIDES  DERIVATIVES  HEPARIN  
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
作者:  Lin,Lisha;  Li,Sujuan;  Gao,Na;  Wang,Weili;  Zhang,Taocui;  Yang,Lian;  Yang,Xingzhi;  Luo,Dan;  Ji,Xu;  Zhao,Jinhua
浏览  |  Adobe PDF(2854Kb)  |  收藏  |  浏览/下载：178/31  |  提交时间：2022/04/02
fucosylated glycosaminoglycan  anticoagulant  platelet aggregation  contact activation  hypotension  pulmonary embolism  CHONDROITIN SULFATE  CONTACT SYSTEM  COMPLEMENT  COAGULATION  ACTIVATION  ACCUMULATION  INVOLVEMENT  DERIVATIVES  KALLIKREIN  THROMBOSIS